Research theme for competitive and other funds (38):
2024 - 2028 口腔腫瘍実質がもたらす間質転換による顎骨破壊機序の解明と治療標的分子の探索
2023 - 2027 Study of the instability among mutant epithelial cells, adjacent normal epithelial cells and stromal cells to develop strategies for screening and very early detection of cancer.
2020 - 2023 Analysis of the signal pathways between oral squamous cell carcinoma cells and surrounding microenvironment as novel therapeutic target for novel anti-cancer therapy
2020 - 2023 Functional analysis and development of novel adenoid cystic carcinoma therapy targeting Wnt signaling
2019 - 2023 The physiological role of p130Cas in salivary gland development
2019 - 2022 A new anti-cancer therapeutic strategy targeting the interrelation between tumorous mechanical extracellular microenvironment and novel oncogene-related gene signaling
2014 - 2017 Novel anticancer therapy targeting specific genes for squamous cell carcinoma
2014 - 2016 Investigation of the effect of Wnt signaling on salivary gland development.
2015 - 2016 肺がん治療を目指した新規核酸医薬品の創出
2014 - 2016 唾液腺上皮組織の発生および再生におけるWntシグナルの役割の解明
2013 - 2014 唾液腺の発生および再生におけるWntシグナルの役割の解明.
2010 - 2013 Development of novel periodontal tissue therapy targeting for regeneration of periodontal ligament.
2010 - 2012 Development of next-generation artificial tooth root including periodontal ligament
2009 - 2011 What is required for periodontal ligament regeneration?
2008 - 2010 Identification of genes related to the regeneration of human periodontalligament tissue
2007 - 2009 ヒト歯根膜組織幹細胞株の分化メカニズムの解明
2007 - 2009 Clarification of the mechanisms of regeneration of periodontal ligament using human clonal periodontal ligament progenitor cell line
2006 - 2008 What are the factor and the cells to be involved in the periodontal regeneration?
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Papers (55):
Yukiko Kami, Toru Chikui, Shinsuke Fujii, Tatsufumi Fujimoto, Wataru Kumamaru, Kana Hasegawa, Koji Nakamatsu, Kazutoshi Okamura, Misa Yasaka, Tamotsu Kiyoshima, et al. Imaging findings in a case of primary intraosseous carcinoma arising from a mandibular cyst. Oral Radiology. 2024
Yusuke Nakako, Kana Hasegawa, Shinsuke Fujii, Yukiko Kami, Taiki Sakamoto, Mizuki Sakamoto, Masafumi Moriyama, Kari J Kurppa, Kristiina Heikinheimo, Kazunori Yoshiura, et al. Wnt/β-catenin-YAP axis in the pathogenesis of primary intraosseous carcinoma NOS, deriving from odontogenic keratocyst. Pathology, research and practice. 2024. 260. 155420-155420
Ryoko Nagano, Yusuke Nakako, Shinsuke Fujii, Shintaro Kawano, Hidefumi Maeda, Tamotsu Kiyoshima. The IL-1β-p65 axis stimulates quiescent odontogenic epithelial cell rests via TGF-β signalling to promote cell proliferation of the lining epithelia in radicular cysts: A laboratory investigation. International endodontic journal. 2024. 57. 3. 344-354
Shinsuke Fujii, Kana Hasegawa, Takashi Maehara, Kari J Kurppa, Kristiina Heikinheimo, Kristy A. Warner, Satoshi Maruyama, Yudai Tajiri, Jacques E. Nör, Jun-ichi Tanuma, et al. Wnt/β-catenin-C-kit axis may play a role in adenoid cystic carcinoma prognostication. Pathology - Research and Practice. 2024. 155148-155148
Thinh Thi Kim Truong, Shinsuke Fujii, Ryoko Nagano, Kana Hasegawa, Megumi Kokura, Yuta Chiba, Keigo Yoshizaki, Satoshi Fukumoto, Tamotsu Kiyoshima. Arl4c is involved in tooth germ development through osteoblastic/ameloblastic differentiation. Biochemical and biophysical research communications. 2023. 679. 167-174
2023/01 - The Journal of Pathology Jeremy Jass Prize for Research Excellence in Pathology in 2021 YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation
2022/06 - 九州大学歯学研究院等 九大歯学優秀研究者賞(IF部門)
2021/10 - 日本病理学会 学術研究賞(A演説)
2009/10 - 日本歯科保存学会 Dentsply賞
2007/05 - 日本歯内療法学会 優秀論文賞
2007/03 - 九州大学歯学府 藤野賞
2006/05 - 株式会社デンツプライ デンツプライ賞
2006/04 - 日本歯科保存学会 日本歯科保存学会奨励賞
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Association Membership(s) (4):
日本臨床細胞学会
, THE JAPANESE SOCIETY OF PATHOLOGY
, JAPANESE ASSOCIATION FOR ORAL BIOLOGY
, 日本臨床口腔病理学会