Rchr
J-GLOBAL ID：201801010745866330   Update date: Jan. 28, 2024

Morimoto Chikao

モリモト チカオ | Morimoto Chikao
Affiliation and department：
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About -


Research field  (3)： Immunology ,  Tumor diagnostics and therapeutics ,  Allergies and connective tissue disease
Research keywords  (8)： 膠原病 ,  自己免疫疾患 ,  ヒト化CD26抗体 ,  悪性胸膜中皮腫 ,  ヒト免疫 ,  T細胞共刺激分子 ,  IL26 ,  CD26/DPPIV
Research theme for competitive and other funds  (31)：
  • 2020 - 2023 ヒト免疫特有の炎症性因子IL-26に基づく慢性炎症病態の解明と新規治療法の開発
  • 2018 - 2021 悪性中皮腫のヒト化CD26抗体療法のための予後・治療効果予測バイオマーカーの開発
  • 2016 - 2019 CD26分子を介した免疫制御機構の解明と自己免疫疾患への臨床応用の基盤研究
  • 2015 - 2018 悪性中皮腫に対するヒト化抗体CD26抗体を基盤とする安全かつ有効な新規併用療法の確立
  • 2014 - 2016 CD26分子の新型コロナウイルス感染症(MERS)への役割及び新規治療法開発
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Papers (201)：
  • Tadasu Okaya, Takeshi Kawasaki, Shun Sato, Yu Koyanagi, Koichiro Tatsumi, Ryo Hatano, Kei Ohnuma, Chikao Morimoto, Yoshitoshi Kasuya, Yoshinori Hasegawa, et al. Functional Roles of CD26/DPP4 in Bleomycin-Induced Pulmonary Hypertension Associated with Interstitial Lung Disease. International Journal of Molecular Sciences. 2024
  • Eiji Kobayashi, Yusuke Kamihara, Miho Arai, Akinori Wada, Shohei Kikuchi, Ryo Hatano, Noriaki Iwao, Takeshi Susukida, Tatsuhiko Ozawa, Yuichi Adachi, et al. Development of a Novel CD26-Targeted Chimeric Antigen Receptor T-Cell Therapy for CD26-Expressing T-Cell Malignancies. Cells. 2023. 12. 16
  • Shohei Kikuchi, Akinori Wada, Yusuke Kamihara, Kosuke Okazaki, Paras Jawaid, Mati Ur Rehman, Eiji Kobayashi, Takeshi Susukida, Tomoki Minemura, Yoshimi Nabe, et al. DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies. Cells. 2023. 12. 7
  • Yu Koyanagi, Takeshi Kawasaki, Yoshitoshi Kasuya, Ryo Hatano, Shun Sato, Yukiko Takahashi, Kei Ohnuma, Chikao Morimoto, Steven M Dudek, Koichiro Tatsumi, et al. Functional roles of CD26/DPP4 in bleomycin-induced pulmonary fibrosis. Physiological reports. 2023. 11. 6. e15645
  • Seiji Kobayashi, Kazunori Fugo, Ryo Hatano, Kazuto Yamazaki, Chikao Morimoto, Hiroyuki Terawaki. Anti-glomerular Basement Membrane Disease Concomitant with MPO-ANCA Positivity Concurrent with High Serum Levels of Interleukin-26 Following Coronavirus Disease 2019 Vaccination. Internal medicine (Tokyo, Japan). 2023. 62. 7. 1043-1048
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MISC (146)：
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Patents (8)：
  • 抗CD26抗体と免疫チェックポイント阻害剤との併用療法
  • 抗癌剤への抵抗性改善剤
  • 免疫チェックポイント阻害剤
  • CD26抗体と他の抗癌剤とを組み合わせた癌治療用組成
  • MERSコロナウイルス感染予防治療剤
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Books (3)：
  • Advanced in Medicine and Biology
    Nova Science Publishers, Inc 2019
  • Advances in Medicine and Biology
    Nova Science Publishers, Inc 2018
  • Horizons in Cancer Research
    Nova Science Publishers, Inc 2017
Professional career (1)：
  • 医学博士 (慶應義塾大学)
Work history (14)：
  • 2012/04 - 現在 The University of Tokyo
  • 2012/04 - 現在 Juntendo University Graduate School of Medicine
  • 2008/08 - 2012/03 The University of Tokyo The Institute of Medical Science
  • 2006/10 - 2012/03 The University of Tokyo The Institute of Medical Science
  • 2000/05 - 2012/03 The University of Tokyo The Institute of Medical Science
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Committee career (3)：
  • - 現在 日本粘膜免疫学会 評議員
  • - 現在 日本リウマチ学会 評議員
  • - 現在 日本免疫学会 評議員
Awards (1)：
  • 2005 - 日本リウマチ学会賞
Association Membership(s) (5)：
日本粘膜免疫学会 ,  THE JAPANESE CANCER ASSOCIATION ,  JAPAN COLLEGE OF RHEUMATOLOGY ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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