Rchr
J-GLOBAL ID:201801010786373607   Update date: Feb. 26, 2024

Yamagishi Makoto

ヤマギシ マコト | Yamagishi Makoto
Affiliation and department:
Homepage URL  (1): https://square.umin.ac.jp/yamagishi/
Research field  (1): Molecular biology
Research keywords  (5): ATL ,  HTLV-1 ,  ゲノム医学 ,  エピジェネティクス ,  ウイルス学
Research theme for competitive and other funds  (11):
  • 2022 - 2025 HAMのシングルセル遺伝子発現解析による疾患特異的な免疫異常発現機構の解明
  • 2021 - 2024 ゲノム異常とエピゲノム異常によるATLの協奏的クローン進化メカニズムの解明
  • 2020 - 2023 HTLV-1関連疾患の発症リスク、進展メカニズムに関するオミックス統合解析と発症予防に資する基盤的研究
  • 2020 - 2023 レトロウイルス病原性と持続感染の根源となる不均一な潜伏集団を生み出す宿主エピゲノム特性の解明と治療薬開発
  • 2019 - 2022 Analysis of genomic and epigenomic regulatory mechanisms that determine abnormal characteristics of HTLV-1-infected cells in HAM.
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Papers (47):
  • Makoto Yamagishi, Yuta Kuze, Seiichiro Kobayashi, Makoto Nakashima, Satoko Morishima, Toyotaka Kawamata, Junya Makiyama, Kako Suzuki, Masahide Seki, Kazumi Abe, et al. Mechanisms of action and resistance in histone methylation-targeted therapy. Nature. 2024
  • Koji Jimbo, Makoto Yamagishi, Yutaka Suzuki, Kako Suzuki, Motoko Mizukami, Kazuaki Yokoyama, Aki Sato, Tokiko Nagamura-Inoue, Yasuhito Nannya, Kaoru Uchimaru. Progression of adult T-cell leukemia/lymphoma from smoldering to acute type due to branched subclonal evolution. EJHaem. 2023. 4. 4. 1188-1190
  • Tomoo Sato, Junji Yamauchi, Naoko Yagishita, Natsumi Araya, Naoki Takao, Yuki Ohta, Eisuke Inoue, Masaki Takahashi, Makoto Yamagishi, Yutaka Suzuki, et al. Long-term safety and efficacy of mogamulizumab (anti-CCR4) for treating virus-associated myelopathy. Brain : a journal of neurology. 2023
  • Makoto Yamagishi. The role of epigenetics in T-cell lymphoma. International journal of hematology. 2022. 116. 6. 828-836
  • Mie Kobayashi-Ishihara, Katarína Frazão Smutná, Florencia E. Alonso, Jordi Argilaguet, Anna Esteve-Codina, Kerstin Geiger, Meritxell Genescá, Judith Grau-Expósito, Clara Duran-Castells, Selina Rogenmoser, et al. Schlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells. Communications biology. 2022. 6. 1. 487-487
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MISC (81):
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Professional career (1):
  • Ph.D.
Work history (6):
  • 2023/04 - 現在 The University of Tokyo Graduate School of Frontier Sciences
  • 2022/04 - 2023/03 The University of Tokyo Graduate School of Frontier Sciences
  • 2018/05 - 2022/03 The University of Tokyo Graduate School of Frontier Sciences
  • 2015/05 - 2018/04 The University of Tokyo Graduate School of Frontier Sciences
  • 2011/04 - 2015/04 The University of Tokyo Graduate School of Frontier Sciences
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Committee career (4):
  • Frontiers in Virology, Systems biology Review Editor
  • Frontiers in Virology, Bioinformatic and Predictive Virology Associate Editor
  • Scientific Reports Editorial Board
  • 日本HTLV-1学会 評議委員
Awards (9):
  • 2017 - 日本血液学会 奨励賞
  • 2017 - 第18回国際ヒトレトロウイルスHTLV会議 優秀口演賞
  • 2017 - 第18回国際ヒトレトロウイルスHTLV会議 優秀ポスター賞
  • 2016 - 米国血液学会 Abstract Achievement Award
  • 2016 - 第3回日本HTLV-1学会学術集会 Young Investigator Award
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