Rchr
J-GLOBAL ID：201801010828676907   Update date: Nov. 12, 2024

MATOBA Keiichiro

マトバ ケイイチロウ | MATOBA Keiichiro
Affiliation and department：
The Jikei University School of Medicine Division of Diabetes, Endocrinology, and Metabolism Department of Internal Medicine

About The Jikei University School of Medicine Division of Diabetes, Endocrinology, and Metabolism Department of Internal Medicine


Job title： Associate Professor
Homepage URL  (1)： http://www.diabendo.jp/
Research theme for competitive and other funds  (21)：
  • 2023 - 2026 Therapeutic effect of ROCK inhibition against the progression of diabetic nephropathy
  • 2023 - 2024 ROCKシグナルによる腎糸球体システム障害の統合的理解
  • 2023 - 2024 血管内皮シグナルによる脂肪組織インスリン抵抗性の病態制御
  • 2022 - 2023 糖尿病腎症におけるROCK シグナルの時間的空間的作用の全貌解明
  • 2022 - 2023 ROCKシグナルの包括的解読による糖尿病性腎症の治療法開発
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Papers (37)：
  • Sekiguchi K, Matoba K*, Nagai Y, Nagao S, Ohashi S, Mitsuyoshi E, Hayashi T, Kawanami D, Yokota T, Shibata H, et al. Rho-associated, coiled-coil-containing protein kinase 2 regulates expression of mineralocorticoid receptor to mediate sodium reabsorption in mice. Biochem Biophys Res Commun. 2024. Online. ahead. of-print
  • Matoba K., Nagai Y., Sekiguchi K., Ohashi S., Mitsuyoshi E., Shimoda M., Tachibana T., Kawanami D., Yokota T., Utsunomiya K., et al. Deletion of podocyte Rho-associated, coiled-coil-containing protein kinase 2 protects mice from focal segmental glomerulosclerosis. 2024. 7. 1. 402
  • Matoba K. Deciphering Rho-associated, coiled-coil-containing protein kinase in diabetic nephropathy: small steps towards a giant leap (Featured article). Endocr J. 2023. 70. 8. 771-776
  • Nagai Y, Matoba K*, Yako H, Ohashi S, Sekiguchi K, Mitsuyoshi E, Sango K, Kawanami D, Utsunomiya K, Nishimura R. Rho-kinase inhibitor restores glomerular fatty acid metabolism in diabetic kidney disease. Biochem Biophys Res Commun. 2023. 649. 32-38
  • Nagai Y, Matoba K*, Takeda Y, Yako H, Akamine T, Sekiguchi K, Kanazawa Y, Yokota T, Sango K, Kawanami D, et al. Rho-associated, coiled-coil-containing protein kinase 1 regulates development of diabetic kidney disease via modulation of fatty acid metabolism. Kidney Int. 2022. 102. 3. 536-545
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Books (41)：
  • Nutrition intervention for diabetic kidney disease: Focusing on clinical stages and pathological features
    Japanese Society for Medical Use of Functional Foods 2024
  • 糖尿病性腎症の進展を制御するROCKシグナル経路
    日本病態生理学会雑誌・日本病態生理学会 2023
  • 糖尿病専門医研修ガイドブック改定第9版
    診断と治療社 2023
  • ROCKシグナルによる糖尿病性腎症の進展機構
    糖尿病合併症・日本糖尿病合併症学会 2023
  • 内分泌代謝・糖尿病内科領域専門医研修ガイドブック
    診断と治療社 2023 ISBN:9784787826046
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Lectures and oral presentations  (59)：
  • Mechanisms of diabetic nephropathy advances in multifactorial intervention
    (2024)
  • 糖尿病の怖さと予防
    (柏市健康講座 2024)
  • 血管-脂肪シグナルを介した糖尿病合併症の抑制
    (第12回糖尿病腎症を考える会 2024)
  • 糖尿病性腎症の進行を加速するメカニズム
    (第20回糖尿病性腎症研究会 2024)
  • Targeting ROCK signaling recovers AMPK/PPARα-driven metabolism in diabetic glomerulopathy
    (2024)
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Education (2)：
  • 2008 - 2013 The Jikei University School of Medicine Post-graduate course
  • 1997 - 2003 The Jikei University School of Medicine
Professional career (1)：
  • Ph.D. (The Jikei University School of Medicine)
Work history (6)：
  • 2023/01 - 現在 The Jikei University Shool of Medicine Division of Diabetes, Endocrinology, and Metabolism Department of Internal Medicine Associate Professor
  • 2017/08 - 2022/12 The Jikei University School of Medicine Division of Diabetes, Endocrinology, and Metabolism Department of Internal Medicine Assistant Professor
  • 2005/04 - 2017/07 The Jikei University School of Medicine Division of Diabetes, Endocrinology, and Metabolism Department of Internal Medicine Research Associate
  • 2016/09 - 2017/03 Case Western Reserve University Shool of Medicine Research Associate
  • 2014/09 - 2016/08 Case Western Reserve University Shool of Medicine Research Scholar
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Awards (8)：
  • 2023/06 - 日本内分泌学会研究奨励賞
  • 2022/10 - 日本糖尿病合併症学会Young Investigator Award
  • 2020/12 - MSD Life Science Foundation Banyu Foundation Research Grant
  • 2019/11 - Japan Medical Association Medical Research Encouragement Prize
  • 2019/03 - Tokyo Medical Association Medical Research Encouragement Prize
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Association Membership(s) (8)：
Japan Society for the Study of Obesity ,  日本糖尿病性腎症研究会(幹事) ,  The Japan Society of Diabetic Complications,JSDC ,  Board Certified Member of Japanese Society for Medical Use of Functional Foods ,  日本医師会(認定産業医) ,  Board Certified Member, Endocrinologist, Educator of The Japan Endocrine Society ,  Board Certified Member, Diabetologist, Educator of The Japan Diabetes Society ,  Board Certified Member, Fellow, Educator of The Japanese Society of Internal Medicine
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