Shinji Kohsaka

コウサカシンジ | Shinji Kohsaka

Affiliation and department：

Research field (1)： Genomics

Research theme for competitive and other funds (9)：

2022 - 2026 次世代トランスクリプトーム解析を用いた肺癌個別化医療開発
2021 - 2024 分子標的治療耐性化メカニズムの網羅的探索
2019 - 2024 Reprogramming of cancer stem cells by high-function hydrogels creates basis to establish novel cancer therapy
2019 - 2023 骨軟部腫瘍の「小胞体ストレス」機能解析に基づいた新規治療法開発
2019 - 2023 がんクリニカルシークエンス解析に基づいた「骨軟部腫瘍分子標的」の作用機序解明

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Papers (196)：

Takeshi Hirose, Masachika Ikegami, Kumiko Kida, Toshihide Ueno, Rina Kitada, Lei Wang, Shinya Tanaka, Makoto Endo, Yasuharu Nakashima, Naoki Kanomata, et al. Cancer risk assessment of premalignant breast tissues from patients with BRCA mutations by genome profiling. NPJ breast cancer. 2024. 10. 1. 87-87
Hidenori Kage, Shinji Kohsaka, Kenji Tatsuno, Kousuke Watanabe, Aya Shinozaki-Ushiku, Hideaki Isago, Tetsuo Ushiku, Hiroyuki Aburatani, Hiroyuki Mano, Katsutoshi Oda. Molecular analysis of non-small cell lung cancer using a dual-targeted DNA and RNA comprehensive genomic profiling panel. Respiratory investigation. 2024. 62. 5. 910-913
Hiroshi Ikeuchi, Yusuke Matsuno, Rika Kusumoto-Matsuo, Shinya Kojima, Toshihide Ueno, Masachika Ikegami, Rina Kitada, Hitomi Sumiyoshi-Okuma, Yuki Kojima, Kan Yonemori, et al. GLI1 confers resistance to PARP inhibitors by activating the DNA damage repair pathway. Oncogene. 2024
Eiji Nakata, Tatsunori Osone, Toru Ogawa, Tomoyuki Taguchi, Kana Hattori, Shinji Kohsaka. Prevalence of neurotrophic tropomyosin receptor kinase (NTRK) fusion gene positivity in patients with solid tumors in Japan. Cancer medicine. 2024. 13. 12. e7351
Shinji Kohsaka, Shigehiro Yagishita, Yukina Shirai, Yusuke Matsuno, Toshihide Ueno, Shinya Kojima, Hiroshi Ikeuchi, Masachika Ikegami, Rina Kitada, Ken-ichi Yoshioka, et al. A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency. npj Precision Oncology. 2024. 8. 1. 117-117

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MISC (43)：

田尾佳代子, 加藤元博, 義岡孝子, 加藤実穂, 久保崇, 高阪真路, 谷田部恭, 瀧本哲也, 市村幸一, 望月慎史, et al. 全国小児がんゲノムプロファイリングプロジェクト JCCG-TOP2(The Nationwide Pediatric Cancer Genome Profiling Project: JCCG-TOP2). 日本癌学会総会記事. 2022. 81回. P-1071
Kazuya Takamochi, Kieko Hara, Takuo Hayahshi, Shinji Kohsaka, Fumiyuki Takahashi, Yoshiyuki Suehara, Kenji Suzuki. The clinical significance of PD-L2 expression in lung adenocarcinoma. CANCER SCIENCE. 2022. 113. 1011-1011
柳垣充, 柳垣充, 荒川歩, 上野敏秀, 大熊ひとみ, 池上徹, 間野博行, 高阪真路. The Assessment of the Clinical Utility of Liquid biopsy Using Circulating Tumor DNA in Pediatric Solid Tumors. 日本癌学会学術総会抄録集(Web). 2022. 81st
長谷川延彦, 高阪真路, 窪田大介, 末原義之, 高木辰哉, 石島旨章. Liquid biopsy in soft tissue and bone tumors. 別冊整形外科. 2021. 79
Taisei Kurihara, Yoshiyuki Suehara, Keisuke Akaike, Takuo Hayashi, Shinji Kohsaka, Nobuhiko Hasegawa, Tatsuya Takagi, Taketo Okubo, Youngji Kim, Takashi Yao, et al. Detection of Fusion Genes in Inflammatory Myofibroblastic Tumor/Inflammatory Pseudotumor by Nanostring-Based Screening System. LABORATORY INVESTIGATION. 2020. 100. SUPPL 1. 59-60

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Lectures and oral presentations (43)：

がんゲノム医療におけるリキッドバイオプシーの有用性と現状
(第62回日本臨床細胞学会総会春期大会 2021)
発がん関連遺伝子における生殖細胞系列バリアントのハイスループット機能解析法
(遺伝性腫瘍セミナー 2021)
Liquid型パネルとC-CATリポジトリの活用
(第18回日本臨床腫瘍学会学術集会 2021)
がん個別化医療の実現に向けた戦略的研究開発
(シンポジウム, AI技術が切り拓く新たなリウマチ学に向けた教育シンポジウム 2021)
がんゲノム医療の現況と展望
(第33回横浜市立大学がんプロ合同セミナー 2020)

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Awards (4)：

2019 - Incitement Award of the Japanese Association of Medical Science
2019 - The Young Scientists’ Prize of the Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology
2018 - Incitement Award of the Japanese Cancer Association
2014 - Incitement Award of the Japanese Association for Molecular Target Therapy of Cancer

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