Research theme for competitive and other funds (8):
2021 - 2024 サイトカイン共通受容体γc鎖によって制御される大腸がん幹細胞の解析
2015 - 2019 AKT signaling in control of ATL tumorigenicity; unveiled mechanism for its heterogenous activation among ATL cell populations
2013 - 2016 Analysis of transformation processes by using the "two-hit leukemogenesis model"
2012 - 2016 Roles of ESCRT in Oncogenesis
2012 - 2015 Regulatory mechanism for intracellar traficking of the membrane-bound NEU3 sialidase
2011 - 2013 Identification of potential marker of cancer stem cell from ovarian clear cell carcinoma
2009 - 2011 Investigation on the molecular mechanism modulating EGFR signal transduction via the membrane-associated sialidase
2008 - 2009 Molecular mechanism of regulation of cancer cell apoptosis by plasma membrane-associated sialidase
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Papers (90):
Mai Mochizuki, Rie Shibuya-Takahashi, Shin-Ichiro Kanno, Shungo Adachi, Haruna Fujimori, Akira Nakazato, Keitaro Fujii, Shinkichi Morita, Satoshi Saijoh, Tomoko Yamazaki, et al. CD271 mRNA/hnRNPA2B1 complex promotes proliferation and stemness in oral and head and neck squamous cell carcinoma. Cancer science. 2024
Haruna Fujimori, Mao Shima-Nakamura, Shin-Ichiro Kanno, Rie Shibuya-Takahashi, Mai Mochizuki, Masamichi Mizuma, Michiaki Unno, Yuta Wakui, Makoto Abue, Wataru Iwai, et al. FAXC interacts with ANXA2 and SRC in mitochondria and promotes tumorigenesis in cholangiocarcinoma. Cancer science. 2024
Shingo Myoen, Mai Mochizuki, Rie Shibuya-Takahashi, Haruna Fujimori, Norihisa Shindo, Kazunori Yamaguchi, Jun Yasuda, Jiro Abe, Takayuki Imai, Ikuro Sato, et al. CD271 promotes proliferation and migration in bladder cancer. Genes to cells : devoted to molecular & cellular mechanisms. 2024. 29. 1. 73-85
Akihiro Yasumoto, Haruna Fujimori, Mai Mochizuki, Rie Shibuya-Takahashi, Mao Nakamura-Shima, Norihisa Shindo, Kazunori Yamaguchi, Daisuke Fukushi, Yuta Wakui, Takahiro Sugai, et al. BEX2 is poor prognostic factor and required for cancer stemness in gastric cancer. Biochemical and biophysical research communications. 2023. 655. 59-67
Shingo Miyabe, Shin Ito, Ikuro Sato, Jiro Abe, Keiichi Tamai, Mai Mochizuki, Haruna Fujimori, Kazunori Yamaguchi, Norihisa Shindo, Hiroshi Shima, et al. Clinical and genomic features of non-small cell lung cancer occurring in families. Thoracic Cancer. 2023