Research theme for competitive and other funds (5)：
2021 - 2024 Development of automated co-culture systems for multiple bacterial species
2020 - 2022 自動培養装置と機械学習による細胞状態のフィードバック制御系の開発
2019 - 2021 Prediction and experimental verification of optimal mutation rate in bacterial evolution
2019 - 2021 Evolvability screening of petroleum/plastic degrading bacteria
2017 - 2019 高変異率実験進化による進化工学的な微生物ゲノム縮小手法の開発
Papers (18)：
Junichiro Iwasawa, Tomoya Maeda, Atsushi Shibai, Hazuki Kotani, Masako Kawada, Chikara Furusawa. Analysis of the evolution of resistance to multiple antibiotics enables prediction of the Escherichia coli phenotype-based fitness landscape. PLoS biology. 2022. 20. 12. e3001920
Yutaro Maeda, Ryo Mizuuchi, Shuji Shigenobu, Atsushi Shibai, Hazuki Kotani, Chikara Furusawa, Norikazu Ichihashi. Experimental evidence for the correlation between RNA structural fluctuations and the frequency of beneficial mutations. RNA (New York, N.Y.). 2022
Atsushi Shibai, Hazuki Kotani, Masako Kawada, Naomi Yokoi, Chikara Furusawa. Development of a device that generates a temperature gradient in a microtiter plate for microbial culture. SLAS Technology. 2022
Atsushi Shibai, Hazuki Kotani, Natsue Sakata, Chikara Furusawa, Saburo Tsuru, D Baltrus. Purifying selection enduringly acts on the sequence evolution of highly expressed proteins in Escherichia coli. G3 Genes|Genomes|Genetics. 2022
Junichiro Iwasawa, Tomoya Maeda, Atsushi Shibai, Hazuki Kotani, Masako Kawada, Chikara Furusawa. Multi-dimensional antibiotic resistance time series reveals the phenotype-based fitness landscape for Escherichia coli. 2022
「細胞を創る」研究会
, 日本ゲノム微生物学会
, SOCIETY OF EVOLUTIONARY STUDIES, JAPAN
, THE BIOPHYSICAL SOCIETY OF JAPAN
, 日本バイオインフォマティクス学会
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
