Research field (2)：
Genomics
, Neuroscience - general
Research keywords (4)：
神経幹細胞
, エピジェネティクス
, 分化
, アストロサイト
Research theme for competitive and other funds (3)：
2021 - 2024 神経幹細胞特異的なエンハンサーによる遺伝子発現制御機構の解明
2018 - 2021 Analysis of DNA methylation changes that determine the differentiation potential of neural stem cells
2012 - 2014 Analysis of neural stem cell fate using whole genome methylation profile
Papers (45)：
Takahito Iga, Hiroshi Kobayashi, Dai Kusumoto, Tsukasa Sanosaka, Nobuyuki Fujita, Ikue Tai-Nagara, Tomofumi Ando, Tomoko Takahashi, Koichi Matsuo, Katsuto Hozumi, et al. Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis. Nature Cell Biology. 2023
Miho Isoda, Tsukasa Sanosaka, Ryo Tomooka, Yo Mabuchi, Munehisa Shinozaki, Tomoko Andoh-Noda, Satoe Banno, Noriko Mizota, Ryo Yamaguchi, Hideyuki Okano, et al. Mesenchymal properties of iPSC-derived neural progenitors that generate undesired grafts after transplantation. Communications biology. 2023. 6. 1. 611-611
Sho Yoshimatsu, Junko Okahara, Junko Yohie, Yoko Igarashi, Ryusuke Nakajima, Tsukasa Sanosaka, Emi Qian, Hiroya Kobayashi, Satoru Morimoto, Noriyuki Kishi, et al. Generation of a Tyrosine Hydroxylase (TH)-2A-Cre Knock-In Non-Human Primate Model by Homology Directed Repair-Biased CRISPR-Cas9 Genome Editing. 2023
Tsukasa Sanosaka, Hironobu Okuno, Noriko Mizota, Tomoko Andoh-Noda, Miki Sato, Ryo Tomooka, Satoe Banno, Jun Kohyama, Hideyuki Okano. Chromatin remodeler CHD7 targets active enhancer region to regulate cell type-specific gene expression in human neural crest cells. Scientific reports. 2022. 12. 1. 22648-22648
Hirosato Ideno, Kent Imaizumi, Hiroko Shimada, Tsukasa Sanosaka, Akisa Nemoto, Jun Kohyama, Hideyuki Okano. Human PSCs determine the competency of cerebral organoid differentiation via FGF signaling and epigenetic mechanisms. iScience. 2022. 25. 10. 105140-105140
