Noriko Motoi

Affiliation and department：
Job title： Deputy Director
Other affiliations (2)：

National Cancer Center Research Institute Visiting Researcher
Saitama Medical University Saitama Medical Center Pathology Visiting Associate Professor

Research field (1)： Human pathology

Research keywords (6)：人体病理学 , Morphology , Cancer genomics , Digital Pathology , Neuroendocrine tumor , Lung Cance

Research theme for competitive and other funds (18)：

2021 - 2024 Development study on pathological predictive biomarkers for cancer treatment
2018 - 2021 Study on pathological indicator to predict response of cancer immune therapy
2018 - 2020 18980565: 未来のがん診療に資する革新的技術を導入したバイオマーカー測定の有用性を評価する大規模前向き観察研究
2018 - 2020 18K07036: がん免疫療法効果予測に資する病理学的指標の探索
2017 - 2019 17824685: 高悪性度神経内分泌肺癌切除例に対する術後補助化学療法の標準治療確立のための研究研究

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Papers (311)：

Kotaro Sugawara, Takashi Fukuda, Chiaki Murakami, Daiji Oka, Takako Yoshii, Gulanbar Amori, Kumiko Ishibashi, Yasuhito Kobayashi, Hiroki Hara, Hiroaki Kanda, et al. Impacts of tumor microenvironment during neoadjuvant chemotherapy in patients with esophageal squamous cell carcinoma. Cancer science. 2024. 115. 8. 2819-2830
Tomoharu Kiyuna, Eric Cosatto, Kanako C. Hatanaka, Tomoyuki Yokose, Koji Tsuta, Noriko Motoi, Keishi Makita, Ai Shimizu, Toshiya Shinohara, Akira Suzuki, et al. Evaluating Cellularity Estimation Methods: Comparing AI Counting with Pathologists’ Visual Estimates. Diagnostics. 2024
Hironori Fukuda, Kosuke Arai, Hideaki Mizuno, Yukari Nishito, Noriko Motoi, Yasuhito Arai, Nobuyoshi Hiraoka, Tatsuhiro Shibata, Yukiko Sonobe, Yoko Kayukawa, et al. Molecular subtypes of lung adenocarcinoma present distinct immune tumor microenvironments. Cancer Science. 2024. 115. 6. 1763-1777
Kana Ohashi, Yukari Nishito, Hironori Fukuda, Ryoichi Sadahiro, Yukihiro Yoshida, Shun-Ichi Watanabe, Noriko Motoi, Yukiko Sonobe, Hideaki Mizuno, Hiroyuki Tsunoda, et al. Neutrophil-to-lymphocyte ratio is a prognostic factor reflecting immune condition of tumor microenvironment in squamous cell lung cancer. Scientific reports. 2024. 14. 1. 429-429
Mitsuyoshi Hirokawa, Masahiro Ito, Noriko Motoi, Tomohiro Chiba, Yoshiaki Imamura, Hironao Yasuoka, Rumi Hino, Miyoko Higuchi, Akira Miyauchi, Takashi Akamizu. Prevalence and diagnostic significance of non-invasive follicular thyroid neoplasm with papillary-like nuclear features in Japan-A multi-institutional study. Pathology International. 2024

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MISC (743)：

野呂林太郎, 本田一文, 本田一文, 長島健悟, 元井紀子, 功刀しのぶ, 松林純, 武内進, 白石英晶, 岡野哲也, et al. Establishment of biomarker for detecting the potential metastasis, and the effect of adjuvant chemotherapy in lung adenocarcinomas with stage I. 日本呼吸器学会誌(Web). 2021. 10
Sayaka Arakawa, Tatsuya Yoshida, Yuko Nakayama, Noriko Motoi, Yuichiro Ohe. Small Cell Cancer Transformation of Lung Adenocarcinoma During Durvalumab Treatment After Chemoradiotherapy. Journal of Thoracic Oncology. 2020. 15. 8. e145-e146
市川晶博, 藤田雄, 保坂悠介, 門田宰, 川本浩徳, 渡邉直昭, 伊藤晶彦, 橋本典生, 皆川俊介, 原弘道, et al. 非小細胞肺癌におけるシャペロン介在性オートファジー(CMA)を介した化学療法耐性機序の検討. 日本呼吸器学会誌. 2020. 9. 増刊. 177-177
Akihiko Miyanaga, Mari Masuda, Noriko Motoi, Koji Tsuta, Yuka Nakamura, Nobuhiko Nishijima, Shunichi Watanabe, Hisao Asamura, Akihiko Tsuchida, Masahiro Seike, et al. Whole-exome and RNA sequencing reveals chromosomal rearrangements associated with the recurrence of pulmonary carcinoid. CANCER RESEARCH. 2020. 80. 16
水野孝昭, 吉田達哉, 元井紀子, 松元祐司, 新野祐樹, 角南久仁子, 小山隆文, 大熊裕介, 後藤悌, 堀之内秀仁, et al. 胸部悪性腫瘍におけるがんゲノムプロファイリング検査(CGP)の実施可能性の検討. 日本肺癌学会総会号. 2020. 61st

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Lectures and oral presentations (11)：

内部に梗塞壊死を伴う胸腺腫の1例
(肺癌 2021)
肺腺がんの転移活性を評価し、術後補助化学療法の効果予測するバイオマーカーの実用化
(日本癌治療学会学術集会抄録集 2021)
肺腺がんの転移活性を評価し,術後補助化学療法の効果を予測するバイオマーカーの実用化に関する後ろ向き研究多施設共同研究
(日本呼吸器学会誌 2021)
IV期原発性肺癌に対してPembrolizumab治療後にsalvage手術を施行した1例
(肺癌 2021)
特徴的な組織像を呈したROS1陽性炎症性筋線維芽細胞腫瘍の1例
(肺癌 2020)

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Education (2)：

1992 - 1996 Graduate School of Medicine and Faculty of Medicine, the University of Tokyo Department of Pathology
1986 - 1992 Kyoto Prefectural University of Medicine

Professional career (1)：

博士(医学) (東京大学大学院医学系研究科病因・病理学専攻)

Work history (15)：

2023/04 - 現在 Saitama Cancer Center Center for Cancer Genomics Director
2021/04 - 現在 National Cancer Center Research Institute Visiting Researcher
2021/04 - 現在 Saitama Cancer Center Department of Pathology Deputy Director
2020/10 - 現在 Saitama Medical University Saitama Medical Center Pathology Visiting Associate Professor
2019/04 - 2021/03 National Cancer Center Hospital Department of Diagnostic Pathology Head

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Committee career (8)：

2022/12 - 現在 Japan Lung Cancer Socirty Committee for International relationship
2021/06 - 現在日本臨床細胞学会学術委員会
2019/04 - 現在 Japan Pathology Society Committe for educational program of molecular pathology
2018/06 - 現在 Japanese Society for Clinical Cytology Working Group on the role of Cytology in the Era of Cancer Genomic Medicine
2018/02 - 現在日本肺癌学会ゲノム時代における呼吸器細胞診検体処理の精度管理ワーキンググループ

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Awards (1)：

2017/10 - Japan Endocrine Pathology Society Kameya Memorial award Pathological study of neuroendocrine tumor of the lung and other organs

Association Membership(s) (11)：

International Association for the Study of Lung Cancer , The Japan Endocrine Society , Japan Endocrine Pathology Society , Pulmonary Pathology Society , The Japan Pulmonary Pathology Society , International Academy of Pathology , United States and Canadian Academy of Pathology , THE JAPANESE CANCER ASSOCIATION , Japanese Society of Clinical Cytology , THE JAPAN LUNG CANCER SOCIETY , THE JAPANESE SOCIETY OF PATHOLOGY

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