Sakai Kazuya

サカイカズヤ | Sakai Kazuya

Affiliation and department：
Job title： Senior lecturer

Research field (1)： Hematology and oncology

Research keywords (5)： Gene therapy , Antigen-specific B-cell isolation , ADAMTS13 , Thrombotic Thrombocytopenic Purpura , von Willebrand factor

Research theme for competitive and other funds (4)：

2021 - 2023 The recognition mechanism of the susceptible HLA in immune-mediated thrombotic thrombocytopenic purpura to ADAMTS13 peptide
2021 - 2021 Validation study of the open ADAMTS13 conformation assay as a novel biomarker for correct diagnosis and predicting relapse in immune mediated thrombotic thrombocytopenic purpura
2019 - 2021 新規von Willebrand因子阻害アプタマーの血栓形成阻害効果の多面的検討
2017 - 2020 Clinical analysis in pathogensisis of gastrointestinal bleeding with severe aortic stenosis according to von willebrand facor

Papers (50)：

齋藤健貴, 酒井和哉, 松本雅則. 【血栓止血領域における抗体医薬】後天性血栓性血小板減少性紫斑病. 臨床検査. 2024. 68. 2. 134-143
長谷川真弓, 谷山歩, 田中宏明, 大前和人, 田邉雅世, 酒井和哉, 松本雅則. 抗D免疫グロブリンを投与されたRhD陰性妊婦の抗体価測定. 日本輸血細胞治療学会誌. 2024. 70. 1. 70-70
Kazuya Sakai. Persistent ADAMTS13 Inhibitor Delays Recovery of ADAMTS13 activity in Caplacizumab-Treated Japanese iTTP Patients. Blood Advances. 2024
濱村貴史, 酒井和哉, 松本雅則. TTP/HUSの発症メカニズム. Thrombosis Medicine. 2023. 13. 4. 259-263
安積秀一, 酒井和哉, 松本雅則. 【微小循環と血栓】TMAの診断と治療. 日本血栓止血学会誌. 2023. 34. 6. 641-653

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MISC (52)：

中村恵理子, 酒井和哉, 松本雅則. 【COVID-19ワクチンと血栓止血異常】COVID-19ワクチンとTTP(新規発症と再燃). Thrombosis Medicine. 2023. 13. 3. 180-184
松本雅則, 宮川義隆, 小亀浩市, 上田恭典, 和田英夫, 日笠聡, 八木秀男, 小川孔幸, 酒井和哉, 宮田敏行, et al. 血栓性血小板減少性紫斑病診療ガイド2023. 臨床血液. 2023. 64. 6. 445-460
濱田恵理子, 酒井和哉, 松本雅則. 【腎臓症候群(第3版)-その他の腎臓疾患を含めて-】先天性・遺伝性腎疾患遺伝性腎疾患遺伝性血栓性血小板減少性紫斑病(Upshaw-Schulman症候群). 日本臨床. 2022. 別冊. 腎臓症候群II. 16-20
濱田恵理子, 山田真也, 酒井和哉, 久保政之, 早川正樹, 松本雅則. 新型コロナウイルスワクチンによる血栓性血小板減少性紫斑病患者への影響. 日本血栓止血学会誌. 2022. 33. 2. 268-268
藤田浩, 西村滋子, 寺谷美雪, 濱田恵理子, 酒井和哉, 松本雅則. 遠心機を使用しないクリオプレシピテート作製術Thaw-siphon変法の改良. 日本輸血細胞治療学会誌. 2022. 68. 2. 324-324

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Lectures and oral presentations (77)：

Immune-mediated TTP patients in remission with recovered ADAMTS13 activity but an open ADAMTS13 conformation are at risk for earlier ADAMTS13 relapse
(Congress of the International Society on Thrombosis and Haemostasis (ISTH) 2023 2023)
ADAMTS13 Conformation and Immunoprofiles in Japanese Patients with Immune-Mediated Thrombotic Thrombocytopenic Purpura
(65th ASH ANNUAL MEETING & EXPOSITION 2022)
免疫原性血栓性血小板減少性紫斑病とHLA
(第29回日本輸血・細胞治療学会秋季シンポジウム 2022)
Relationship between recurrence of congenital and immune-mediated thrombotic thrombocytopenic purpura and mRNA-based COVID-19 vaccination : A questionnaire survey in a Japanese cohort
(Immunoprofiles and open ADAMTS13 in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura 2022)
Immunoprofiles and open ADAMTS13 in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura
(Congress of the International Society on Thrombosis and Haemostasis (ISTH) 2022 2022)

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Education (2)：

2016 - 2020 Nara Medical University Graduate School of Medical Science Course
2005 - 2011 Nara Medical University Medical Faculty Medical Department

Professional career (1)：

博士(医学) (奈良県立医科大学大学院医学研究科)

Work history (6)：

2023/04 - 現在 Nara Medical University Department of Blood Transfusion Medicine Senior lecturer
2021/06 - 2023/03 Katholieke Universiteit Leuven Chemistry, Kulak Kortrijk Campus Postdoctoral Fellow
2017/02 - 2021/06 Nara Medical University Department of Blood Transfusion Medicine
2016/04 - 2017/02 Nara medical university Department of Blood Transfusion Medicine
2013/04 - 2016/03 Kurashiki Central Hospital Deapartment of Hematology

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Awards (9)：

2023/02 - 日本学術振興会(JSPS) 令和4年度海外特別研究員人種横断的な免疫原性血栓性血小板減少性紫斑病における網羅的な免疫プロファイル解析
2021/09 - 日本血液学会令和3年度日本血液学会奨励賞 HLA-DR molecules with different binding motif could recognize shared ADAMTS13 peptide to develop TTP
2021/09 - 日本組織適合性学会 2021年度日本組織適合性学会学術奨励賞(最優秀賞) 日本人の後天性血栓性血小板減少性紫斑病患者における疾患感受性HLAアリルの同定及び高親和性ADAMTS13ペプチドのin silico解析
2021/06 - 奈良県立医科大学医学部医学科同窓会令和3年度厳橿学術奨励賞
2021/05 - The Young Investigator Award for the Year of 2021, JSTH

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Association Membership(s) (7)：

Belgian society of thrombosis and hemostasis , International Society of Thrombosis and Haemostasis , THE JAPAN SOCIETY OF TRANSFUSION MEDICINE AND CELL THERAPY , THE JAPANESE SOCIETY ON THROMBOSIS AND HEMOSTASIS , THE JAPANESE SOCIETY OF HEMATOLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , 日本組織適合性学会

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