Saito Kozo

Affiliation and department：
Other affiliations (1)：

Research field (3)： Neuroscience - general , Pharmacology , Neurology

Research keywords (5)： Alexander disease , Astrocytes , Genetic disorder , Glia , Neurodegenerative disease

Research theme for competitive and other funds (5)：

2022 - 2025 Research on the role of microglia in "primary astrocytic disease" Alexander disease
2019 - 2022 In vivo imaging analysis of neuron-glia dynamics in neurological disease models
2021 - 2022 アストロサイト・ミクログリア機能イメージングによるアレキサンダー病の分子病態解明
2020 - 2021 「先進ゲノム支援」(先進ゲノム解析研究推進プラットフォーム)支援課題採択
2020 - 2021 アストロサイト・ニューロン・ミクログリア三者相互作用の病態解明によるアレキサンダー病治療開発戦略

Papers (27)：

Yen-Phung Le, Kozo Saito (co-first author), Bijay Parajuli, Kent Sakai, Yuto Kubota, Miho Miyakawa, Youichi Shinozaki, Eiji Shigetomi, Schuichi Koizumi. Severity of Peripheral Infection Differentially Affects Brain Functions in Mice via Microglia-Dependent and -Independent Mechanisms. International Journal of Molecular Sciences. 2023. 24. 24. 17597-17597
Kozo Saito, Eiji Shigetomi, Youichi Shinozaki, Kenji Kobayashi, Bijay Parajuli, Yuto Kubota, Kent Sakai, Miho Miyakawa, Hiroshi Horiuchi, Junichi Nabekura, et al. Microglia sense astrocyte dysfunction and prevent disease progression in an Alexander disease model. Brain. 2023. 147. 2. 698-716
Kozo Saito, Schuichi Koizumi. A promising drug for neuropathic pain: identification of vesicular nucleotide transporter as a novel target of eicosapentaenoic acid. Purinergic Signalling. 2023. 19. 4. 587-589
Youichi Shinozaki, Kozo Saito, Kenji Kashiwagi, Schuichi Koizumi. Ocular P2 receptors and glaucoma. Neuropharmacology. 2022. 222. 109302-109302
Yuji Tanaka, Takashi Ando, Kazuki Mochizuki, Satoshi Igarashi, Kyoichiro Tsuchiya, Kozo Saito, Yasumi Ito, Zentaro Yamagata, Masaru Iwasaki, YHAB Health Data Survey Group 2020. Super-multifactorial survey YHAB revealed high prevalence of sleep apnoea syndrome in unaware older adults and potential combinatorial factors for its initial screening. Frontiers in Aging. 2022. 3

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MISC (37)：

Saito Kozo, Shigetomi Eiji, Shinozaki Youichi, Parajuli Bijay, Koizumi Schuichi. The mechanisms of which microglia are related to the pathology in the "primary astrocytic disease" Alexander disease. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. YIA08-5
Saito Kozo, Shigetomi Eiji, Koizumi Schuichi. Microglial Ca²⁺ signals in Alexander disease model. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 1-P-021
Saito Kozo, Shigetomi Eiji, Koizumi Schuichi. Research on the molecular pathogenesis of "primary astrocyte disorder" Alexander disease. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2020. 93. 1-S13-4
横出晃能, 辻有希子, 前園恵子, 安田怜, 藤並潤, 齋藤光象, 水野敏樹. 眼球運動時痛による眼球運動制限を伴ったFisher症候群の1例. 臨床神経学(Web). 2019. 59. 4
繁冨英治, 齋藤光象, 小泉修一. アストロサイトの異常カルシウムシグナルとその病態生理学的意義. 日本薬理学雑誌. 2019. 154. Supplement

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Education (2)：

2012 - 2016 Kyoto Prefectural University of Medicine Graduate School of Medical Science Department of Neurology
2000 - 2006 Kyoto Prefectural University of Medicine

Professional career (1)：

Work history (5)：

2024 - 現在 University of Yamanashi Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine
2019 - 2024 University of Yamanashi Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine Research Associate
2017 - 2019 Kyoto Prefectural University of Medicine
2016 - 2017 Kyoto Prefectural University of Medicine
2006 - 2008 京都第一赤十字病院臨床研修医

Awards (1)：

Association Membership(s) (5)：

日本神経治療学会 , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , 日本神経免疫学会 , JAPANESE SOCIETY OF NEUROLOGY

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