Research theme for competitive and other funds (19)：
2021 - 2024 エピジェネティック因子による間接的DNA損傷修復機構の解明
2019 - 2022 Functional analyses of enzymatic activity- and complex formation-dependent roles of UTX in the regulation of hematopoietic stem cells and development of hematopoietic diseases
Nakata Y#, Ueda T, Sera Y, Kanai A, Ikeda K, Yamasaki N, Nagamachi A, Kobatake K, Taguchi M, Sotomaru Y, Ichinohe T, Honda Z, Manabe I, Suda T, Takubo K, Kaminuma O, Honda H#. JMJD3 mediated senescence is required to overcome stress induced hematopoietic defects. bioRxiv. 2024
Nakata Y, Nagasawa S, Sera Y, Yamasaki N, Kanai A, Kobatake K, Ueda T, Koizumi M, Manabe I, Kaminuma O, et al. PTIP epigenetically regulates DNA damage-induced cell cycle arrest by upregulating PRDM1. Sci Rep. 2024. 14. 17987. 17987-17987
Caeiro L, Nakata Y, Borges RL, Garcia-Martinez L, Banuelos C, Stransky S, Chan HL, Brabson J, Dominguez D, Zhang Y, et al. Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma. Genes Dev. 2024. 38. 1-2. 46-69
Mas G, Man N, Nakata Y, Martinez-Caja C, Karl DL, Beckedorff F, Tamiro F, Chen C, Duffort S, Itonaga H, et al. The SWI/SNF chromatin remodeling subunit DPF2 facilitates NRF2-dependent anti-inflammatory and anti-oxidant gene expression. J Clin Invest. 2023. 133. 13. e158419
Yuichiro Nakata, Norimasa Yamasaki, Takeshi Ueda, Kenichiro Ikeda, Akiko Nagamachi, Toshiya Inaba, Hiroaki Honda. JMJD3 Plays Essential Roles in the Maintenance of Hematopoietic Stem Cells and Leukemic Stem Cells through the Regulation of p16(INK4a). BLOOD. 2016. 128. 22
Yuichiro Nakata, Takeshi Ueda, Akiko Nagamachi, Linda Wolff, Ogawa Seishi, Toshiya Inaba, Hiroaki Honda. Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBLQ367P. BLOOD. 2014. 124. 21
長町 安希子, 上田 健, 山崎 憲政, 中田 雄一郎, 海老原 康広, 辻 浩一郎, 田久保 圭誉, 須田 年生, 稲葉 俊哉, 本田 浩章. NF-κBに対するユビキチン修飾酵素A20はアポトーシスと炎症の抑制により成体造血の恒常性維持に重要な役割を果たす(A20 plays critical roles in the homeostatic maintenance of adult hematopoiesis by prohibiting apoptosis and inflammation). 日本癌学会総会記事. 2013. 72回. 232-232
Dysregulation of transcription and genome stability caused by H3K36M in head and neck squamous cell carcinoma
(2023 Florida Academic Cancer Center Alliance (FACCA) Annual Retreat 2023)
Dysregulation of transcription and genome stability caused by H3K36M in head and neck squamous cell carcinoma
(The 5th Biennial Miami Epigenetics and Cancer Symposium 2022)
Epigenetic dysregulation associated with H3K36M in head and neck squamous cell carcinoma
(2021 Sylvester Annual Retreat Communication 2021)
- 2015 Hiroshima University Graduate School of Biomedical & Health Sciences
Professional career (1)：
医学 (広島大学)
Work history (6)：
2023/10 - 現在 東京女子医科大学 実験動物研究所 客員講師
2023/07 - 現在 千葉大学大学院 医学研究院 疾患システム医学 特任助教
2020/01 - 2023/07 University of Miami-Miller School of Medicine, Sylvester Comprehensive Cancer Center Cancer Epigenetics Program Chromatin Dynamics in Stem Cells and Cancer Lab Postdoctoral fellow
2017/04 - 2020/01 Research Institute for Radiation Biology and Medicine, Hiroshima University Department of Disease Model Assistant Professor
2015/10 - 2017/03 Japan Society for the Promotion of Science Postdoctoral fellow (PD)
2015/04 - 2015/09 Japan Society for the promotion of Science Postdoctoral fellow (DC2)
