Rchr
J-GLOBAL ID：201801011501613495
Update date: Nov. 12, 2024
Nakayama Yuji
ナカヤマ ユウジ | Nakayama Yuji
Affiliation and department：
Homepage URL (1)：
http://labo.kyoto-phu.ac.jp/seika/saito/homu.html
Research field (1)：
Pharmaceuticals - health and biochemistry
Research keywords (7)：
細胞周期
, チロシンリン酸化
, Src
, 細胞分裂
, シグナル伝達
, 細胞生物学
, 生化学
Research theme for competitive and other funds (17)：
- 2024 - 2027 がん細胞に特徴的な細胞分裂におけるコレステロール生合成経路の意義解明
- 2024 - 2027 Reveal the Mechanism of cancer cell division and examination of therapeutic application
- 2019 - 2023 Rad17 ATPaseの解析からDNA損傷応答を標的とするシード化合物への展開
- 2019 - 2022 Regulation of cell division by the receptor-type tyrosine kinase
- 2015 - 2020 Src family kinase-driven inactivation of the DNA damage checkpoint and novel cancer therapeutics
- 2016 - 2019 Regulation of cell division by tyrosine phosphorylation signaling
- 2014 - 2018 Regulation of neuronal ageing through the mTOR signaling by acetylation
- 2014 - 2017 Analysis of the mechanism by which mutations of the FAM83H gene cause amelogenesis imperfecta
- 2013 - 2016 Regulation of cell division by Src signaling and its role in the cancer malignancy
- 2011 - 2012 Is the Lyn-ACSL3 system involved in induction of cell polarization ?
- 2010 - 2012 Regulation of cell division by tyrosine phosphorylation signaling and its role in cancer development
- 2009 - 2011 Sorting of tyrosine kinases to organelles and signal transduction
- 2007 - 2009 Regulation of cell division by tyrosine phosphorylation-mediated control of organelle dynamics
- 2007 - 2008 Sorting mechanism of subcellular localization of tyrosine kinases and signal transduction
- 2005 - 2006 Chkチロシンキナーゼによるリン酸化と細胞周期制御機構との関連についての研究
- 2005 - 2006 Intracellular trafficking of tyrosine kinases and their differential functions
- 2003 - 2004 Chkキナーゼにより誘導される核形態異常と細胞分裂異常についての解析
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Papers (136)：
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Sakura Yanagida, Ryuzaburo Yuki, Youhei Saito, Yuji Nakayama. LAT1 supports mitotic progression through Golgi unlinking in an amino acid transport activity-independent manner. The Journal of biological chemistry. 2024. 300. 10. 107761-107761
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Junna Tanaka, Hiroki Kuwajima, Ryuzaburo Yuki, Yuji Nakayama. Simvastatin activates the spindle assembly checkpoint and causes abnormal cell division by modifying small GTPases. Cellular signalling. 2024. 119. 111172-111172
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Takahiro Kitagawa, Takahiro Matsumoto, Tomoe Ohta, Tatsusada Yoshida, Youhei Saito, Yuji Nakayama, Yuki Hadate, Eishi Ashihara, Tetsushi Watanabe. Linderapyrone analogue LPD-01 as a cancer treatment agent by targeting importin7. Journal of Natural Medicines. 2024
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Ryuzaburo Yuki, Hiroki Kuwajima, Ryoko Ota, Yuki Ikeda, Youhei Saito, Yuji Nakayama. Eph signal inhibition potentiates the growth-inhibitory effects of PLK1 inhibition toward cancer cells. European Journal of Pharmacology. 2024. 963. 176229-176229
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Nanami Hasegawa, Mayue Hongo, Misaki Okada, Takahisa Kuga, Yuichi Abe, Jun Adachi, Takeshi Tomonaga, Naoto Yamaguchi, Yuji Nakayama. Phosphotyrosine proteomics in cells synchronized at monopolar cytokinesis reveals EphA2 as functioning in cytokinesis. Experimental Cell Research. 2023. 432. 1. 113783-113783
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MISC (9)：
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幸龍三郎, 中山祐治. Role of nuclear tyrosine phosphorylation signaling in cancer progression. 京都薬科大学紀要(Web). 2021. 2. 1
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北川翔大, 松本崇宏, 今堀大輔, 齊藤洋平, 中山祐治, 芦原英司, 渡辺徹志. フキ(Petasites japonicus)地上部含有がん再発予防成分の探索. 和漢医薬学会学術大会要旨集. 2020. 37th
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今堀大輔, 松本崇宏, 阿知波香月, 齊藤洋平, 小島直人, 山下正行, 中山祐治, 渡辺徹志. オオハマボウ(Hibiscus tiliaceus)幹および枝より得られた成分のがん細胞増殖抑制および細胞死の誘導作用. 和漢医薬学会学術大会要旨集. 2020. 37th
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今堀大輔, 松本崇宏, 阿知波香月, 齊藤洋平, 小島直人, 山下正行, 中山祐治, 渡辺徹志. Inhibitory effects on cell proliferation and cell death-inducing activities of constituents from Hibiscus tiliaceus. 衛生薬学・環境トキシコロジー講演要旨集. 2020. 2020
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北川翔大, 松本崇宏, 今堀大輔, 齋藤洋平, 中山祐治, 芦原英司, 渡辺徹志. Cytotoxic activities against cancer stem cells of isolated compounds from dried aerial parts of Petasites japonicus. 衛生薬学・環境トキシコロジー講演要旨集. 2020. 2020
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Professional career (1)：
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