Takushi Hanita

ハニタタクシ | Takushi Hanita

Research field (1)： Fetal medicine/Pediatrics

Research theme for competitive and other funds (21)：

2022 - 2025 人工赤血球を人工胎盤のプライミング液に用いた人工子宮システムの有用性の検討
2022 - 2025 人工子宮・人工胎盤システム管理下胎児治療(カテーテル手術)の安全性の検討
2022 - 2025 人工子宮システムに胎盤の排泄機能として付与する持続血液透析の有効性の検討
2021 - 2024 人工子宮装置を用いた胎児発育遅延モデルにおける脳障害の解析
2021 - 2024 胎生期の脳subplate損傷における過成熟反応の解析

2021 - 2024 人工赤血球を人工胎盤のプライミング液に用いた人工子宮システムの有用性の検討

2019 - 2023 Investigation of the pathophysiology and the treatment for pulmonary fibrosis associated with bronchopulmonary dysplasia

2019 - 2022 Development of an artificial womb system to support extremely preterm ovine fetuses

2019 - 2022 Investigation of the safety of fetal surgery managed the artificial uterus/placenta system

2017 - 2021 Analysis of the influence of intrauterine inflammation to adrenal function in preterm fetal infants

2017 - 2021 The histopathological changes of fetal lung induced by antenatal betamethasone treatment

2017 - 2020 Development of newborn resuscitation using extracorporeal circulation device maintaining fetal circulation

2017 - 2020 Potential role of subplate neuronal damage on the fetal brain development

2016 - 2019 Elucidation the promoter of ductus arteriosus remodeling in fetal sheep

2016 - 2019 Safety assessment of bringing up the sheep fetus with ex vivo uterine environment for a long term

2015 - 2019 Elucidation of the mechanism of developmental fetal organ damage caused by stress-induced overmaturation

2015 - 2017 A possible device for neonatal resuscitation using a pumpless artificial placenta system

2014 - 2017 Potential role of subplate neuronal damage on the fetal cortical development

2014 - 2017 Pathogenesis of insufficient adrenocortical response in premature sheep fetus

2006 - 2007 The effect of intrauterine inflammation on fetal cerebral hemodynamics and white matter injury in the chronically instrumented fetal sheep

2001 - 2002 各種新生児肺障害モデルに対するITPV,HFOV,NO併用効果の検討

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Papers (44)：

Hideyuki Ikeda, Shimpei Watanabe, Shinichi Sato, Erin L Fee, Sean W D Carter, Yusaku Kumagai, Tsukasa Takahashi, Shinichi Kawamura, Takushi Hanita, Sebastian E Illanes, et al. Upregulation of hepatic nuclear receptors in extremely preterm ovine fetuses undergoing artificial placenta therapy. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2024. 37. 1. 2301651-2301651
Haruo Usuda, Hideyuki Ikeda, Shimpei Watanabe, Shinichi Sato, Erin L. Fee, Sean W. D. Carter, Yusaku Kumagai, Yuya Saito, Tsukasa Takahashi, Yuki Takahashi, et al. Artificial placenta support of extremely preterm ovine fetuses at the border of viability for up to 336 hours with maintenance of systemic circulation but reduced somatic and organ growth. Frontiers in Physiology. 2023. 14
Shinichi Sato, Shimpei Watanabe, Yuya Saito, Aika Takanashi, Hideyuki Ikeda, Yoshie Sakurai, Shouta Koshinami, Yusaku Kumagai, Haruo Usuda, Takushi Hanita, et al. High Expression of Adrenal Cortisol Synthases Is Acquired After Intrauterine Inflammation in Periviable Sheep Fetuses. Journal of the Endocrine Society. 2023. 7. 9. bvad100
萩原基実, 大久保龍二, 矢内敦, 武蔵尭志, 熊坂衣織, 萩野有正, 高梨愛佳, 桜井愛惠, 越浪正太, 佐藤信一, et al. 先天性食道閉鎖症と先天性十二指腸閉鎖症を合併した極低出生体重児の一例. 日本周産期・新生児医学会雑誌. 2023. 59. Suppl.1. P408-P408
Yusaku Kumagai, Matthew W Kemp, Haruo Usuda, Tsukasa Takahashi, Yuki Takahashi, Hirotaka Hamada, Augusto F Schmidt, Takushi Hanita, Shimpei Watanabe, Shinichi Sato, et al. A Reduction in Antenatal Steroid Dose Was Associated with Reduced Cardiac Dysfunction in a Sheep Model of Pregnancy. Reproductive sciences (Thousand Oaks, Calif.). 2023

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MISC (122)：

渡邊真平, 臼田治夫, 池田秀之, 佐藤信一, 埴田卓志, 呉繁夫, 熊谷祐作, 齋藤昌利, ケンプマシュー, 川村慎一. Successful use of artificial uterus to support extremely preterm ovine fetuses. 日本小児科学会雑誌. 2021. 125. 2
Yusaku Kumagai, Haruo Usuda, Shinnichi Sato, Takushi Hanita, Sean Carter, Erin L. Fee, Gabrielle C. Musk, Nobuo Yaegashi, Alan H. Jobe, John P. Newnham, et al. Alterations in Fetal Ovine Cardiac Function and Gene Expression following Antenatal Steroid Exposure. REPRODUCTIVE SCIENCES. 2020. 27. SUPPL 1. 327A-327A
Shinichi Sato, Takushi Hanita, Hideyuki Ikeda, Tsukasa Takahashi, Yusaku Kumagai, Haruo Usuda, Shimpei Watanabe, Masatoshi Saito, Matsuda Tadashi. Intrauterine Inflammation Enhances Fetal Cortisol Response to Corticotropin-releasing Hormone in the Extremely Preterm Ovine Fetus. REPRODUCTIVE SCIENCES. 2020. 27. SUPPL 1. 155A-155A
星合哲郎, 齋藤昌利, 岩間憲之, 濱田裕貴, 八重樫伸生, 埴田卓志, 浜崎洋一, 谷川原真吾, 崔佳苗実. 宮城県における未受診妊婦・飛び込み分娩に関する検討~児童虐待予防の新たな対策~. 日本周産期・新生児医学会雑誌(Web). 2020. 56. Suppl.2
Yusaku Kumagai, Masatoshi Saito, Haruo Usuda, Shimpei Watanabe, Shinichi Sato, Takushi Hanita, Gabrielle C. Musku, Sean Carter, Nobuo Yaegashi, Alan H. Jpbe, et al. Alterations in Fetal Cardiac Function Following Antenatal Steroid Treatments in a Sheep Model of Pregnancy. REPRODUCTIVE SCIENCES. 2019. 26. 248A-248A

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Professional career (1)：

Doctor of Phylosophy (Medical Science) (Tohoku University)

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