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J-GLOBAL ID：201801011609342196   Update date: Nov. 14, 2024

HAYASHI Mitsuhiro

ハヤシ ミツヒロ | HAYASHI Mitsuhiro
Affiliation and department：
Yotsuya Medical Cube Breast Surgery, Women's Center

About Yotsuya Medical Cube Breast Surgery, Women's Center


Job title： Chief of Breast Surgery
Research field  (2)： Tumor biology ,  General surgery, pediatric surgery
Research keywords  (9)： 早期発見 ,  Scarless Breast Surgery ,  Imaging ,  Breast cancer ,  Translational research ,  Elastography ,  Liquid biopsy ,  Metabolomics ,  Patient-derived xenograft model
Research theme for competitive and other funds  (7)：
  • 2018 - 2022 Establishing novel molecular-targeted cancer therapies based on molecular diagnostics focusing on prognostic factor CYLD
  • 2018 - 2019 Reverse Translational Research on cirulating tumor DNA using Breast Cancer Patient-derived Tumor models
  • 2018 - 2019 Developing Standards for Mass Spectrometry Imaging in Pharmaceutical Research
  • 2016 - 2017 Development of Evaluation System for Pharmakokinetics and Tumor Microenvironment in Treatment Resistance Tumors using Molecular Imaging
  • 2017 - Deciphering and Targeting the Link between Obesity and Cancer
Show all
Papers (55)：
  • Makoto Ohno, Yoshiharu Hayashi, Hiroaki Aikawa, Mitsuhiro Hayashi, Yasuji Miyakita, Masamichi Takahashi, Yuko Matsushita, Akihiko Yoshida, Kaishi Satomi, Koichi Ichimura, et al. Tissue 2-Hydroxyglutarate and Preoperative Seizures in Patients With Diffuse Gliomas. Neurology. 2021. 97. 21. e2114-e2123
  • 新垣 ひとみ, 桑野 明香里, 平井 ちか, 末永 尚輝, 金丸 歩美, 三宅 俊介, 林 光博, 齋藤 秀之, 城野 博史, 成田 勇樹. CYLD発現低下による予後不良トリプルネガティブ型乳癌に対するNF-κBシグナル標的治療の有効性. 臨床化学. 2021. 50. Suppl.1. 209-209
  • 大野 誠, 林 善治, 相川 博明, 林 光博, 宮北 康二, 高橋 雅道, 松下 裕子, 吉田 朗彦, 里見 介史, 市村 幸一, et al. 脳腫瘍と微小環境 悪性神経膠腫における組織2-hydroxyglutarate濃度と痙攣発症の検討. Brain Tumor Pathology. 2021. 38. Suppl. 055-055
  • Akari Kuwano, Hirai Chika, Suenaga Naoki, Kanemaru Ayumi, Arakaki Hitomi, Hayashi Mitsuhiro, Saigou Chika, Saitou Hideyuki, Jono Hirofumi. Biological significance of CYLD downregulation in Triple negative breast cancer. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2021. 94. 1-Y-E3-2
  • Mitsuhiro Hayashi. Developing breast cancer guidelines: keep cherishing our former knowledge as we continue to acquire new. Translational Breast Cancer Research. 2020. 1. 23-23
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MISC (65)：
  • 林 光博, 大野 誠, 市村 幸一, 吉田 朗彦, 成田 善孝. 質量分析イメージングを用いた脳腫瘍組織内の2-ヒドロキシグルタル酸局在解析(Evaluation of the tissue distribution of oncometabolite 2-hydroxyglutarate in gliomas using mass spectrometry imaging). 日本癌学会総会記事. 2018. 77回. 1263-1263
  • 城野博史, 城野博史, 平井ちか, 西郷智香, 林光博, 林光博, 神力悟, 安東由喜雄, 岩瀬弘敬, 齋藤秀之, et al. 乳癌薬物療法に対する耐性獲得における生命予後規定因子CYLD発現低下の臨床的意義の解明. 医療薬学フォーラム講演要旨集. 2018. 26th
  • 西郷智香, 平井ちか, 桑野明香理, 林光博, 岩瀬弘敬, 齋藤秀之, 城野博史. 乳癌薬物療法における癌抑制遺伝子CYLD発現低下の臨床的意義の解明. 日本医療薬学会年会講演要旨集(Web). 2018. 28
  • Mitsuhiro Hayashi, Yukari Tsubata, Hiroaki Aikawa, Kenji Tamura, Yasuhiro Fujiwara, Takeshi Isobe. Heterogeneous tissue distributions of erlotinib in lung cancer using MALDI mass spectrometry imaging. CANCER SCIENCE. 2018. 109. 902-902
  • M. Takahashi, S. Miki, K. Fukuoka, M. Yasukawa, M. Hayashi, A. Mukasa, R. Nishikawa, K. Tamura, Y. Narita, K. Masutomi, et al. DEVELOPMENT OF TERT-TARGETING THERAPY USING ERIBULIN MESYLATE IN MOUSE GLIOBLASTOMA MODEL. NEURO-ONCOLOGY. 2017. 19. 2-2
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Lectures and oral presentations  (8)：
  • Patient-derived xenograft models for drug development: J-PDX library
    (The Japanese Society of Medical Oncology Annual Meeting 2019)
  • Value of elastography can predict response to neoadjuvant chemotherapy in breast cancer?
    (Annual Scientific Meeting of the Japan Society of Ultrasonics in Medicine 2016)
  • Correlations between elastographic evaluations and clinicopathological factors in breast cancer
    (Asian Federation of Societies for Ultrasound in Medicine and Biology Congress 2016)
  • Evaluation of tissue drug distribution by mass spectrometry imaging
    (The 31th Annual Meeting of the Japanese Society for the Study of Xenobiotics 2016)
  • Correlation between clinical tumor stiffness by elastography and response to neoadjuvant chemotherapy in patients with breast cancer
    (50th Annual Meeting of the American Society of Clinical Oncology 2014)
ｍore...
Professional career (2)：
  • MD
  • PhD
Work history (4)：
  • 2020/04 - Yotsuya Medical Cube Breast Surgery Chief
  • 2019/10 - 2020/03 Kumamoto City Hospital Breast and Endocrine Surgery Chief
  • 2015/04 - 2019/09 National Cancer Center, Japan Exploratory Oncology Research and Clinical Trial Center Staff Scientist / Medical Doctor
  • 2014/04 - 2015/03 Graduate School of Medical Sciences, Kumamoto University Breast and Endocrine Surgery Assistant professor
Association Membership(s) (8)：
New York Academy d Sciences ,  American Association for Cancer Research ,  American Society of Clinical Oncology ,  Japan Society of Clinical Oncology ,  Japanese Society of Medical Oncology ,  Japanese Cancer Association ,  Japanese Breast Cancer Society ,  Japan Surgical Society
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