Job title:
准教授
Research theme for competitive and other funds (27):
2024 - 2028 ICI耐性NSCLCにおけるSiglec-9の役割
2024 - 2027 Developmental transition of spinogenesis and spine plasticity in the neorcortex
2022 - 2027 Development of novel therapies for ENL-mutated Wilms tumor
2022 - 2025 Identification of histone modifications responsible for local chromatin compaction affecting transcriptional states
2022 - 2025 Mechanisms of AF10-rearranged leukemia
2021 - 2024 シグナル感知エピゲノム酵素による世代を超えた環境適応機構の解明
2021 - 2024 Identification of cancer-specific neoantigens in organoid culture
2020 - 2024 Generation of a high-resolution genome map using haploid and hybrid organisms and its application to genetic analysis
2019 - 2022 Long noncoding RNAs involved in the pathogenesis of infectious uveitis
2019 - 2022 Mechanisms of MLL-rearranged leukemia
2018 - 2021 A novel approach using aptamers for histone code analysis
2016 - 2021 Elucidation of lifestyle-related diseases development due to environmental factors and epigenetic memory
2016 - 2018 Elucidation of chromatin dynamics by an energy sensor histone demethylase
2015 - 2018 The role of the heterotrimeric G protein, Galpha12/13 in differentiation and proliferation of smooth muscle cells.
2013 - 2018 Dynamics of Molecular Pattern Recognition in Protein Interaction
2013 - 2018 The function of histone demethylase JMJD1A as a signal-sensing scaffold
2016 - 2017 生活習慣病発症における環境と栄養を感知するエピゲノム制御機構の解明
2014 - 2016 Elucidation of locus specific chromatin complex formation and energy expenditure gene expressions using enChIP
2012 - 2016 p115RhoGEF promote differentiation of human acute leukemic cells
2010 - 2016 The Epigenomic Analysis of Obesity and Insulin Resistance
2009 - 2012 Histone demethylase Jmjd1a as a regulator of glycolipid metabolism
2008 - 2012 Dynamic Proteomics of Transcriptional and Nuclear Architecture
2009 - 2011 The function of LARG in the nucleus
2010 - 2010 肥満発症と脂肪細胞分化におけるエピジェネティックスの解明
2008 - 2009 Comprehensive analyses of signals of Wnt and nuclear receptors in adipogenesis through proteomics
2007 - 2008 Analysis of phosphorylation signaling pathways
1999 - 2000 若年性パーキンソン病原因タンパク質の構造と生理作用
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Papers (93):
Juri Sakata, Toshifumi Tatsumi, Akira Sugiyama, Akihiro Shimizu, Yuya Inagaki, Hiroto Katoh, Takefumi Yamashita, Kazuki Takahashi, Sho Aki, Yudai Kaneko, et al. Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin. Protein expression and purification. 2023. 106375-106375
Yuta Tani, Morihito Takita, Yurie Kobashi, Masatoshi Wakui, Tianchen Zhao, Chika Yamamoto, Hiroaki Saito, Moe Kawashima, Sota Sugiura, Yoshitaka Nishikawa, et al. Varying Cellular Immune Response against SARS-CoV-2 after the Booster Vaccination: A Cohort Study from Fukushima Vaccination Community Survey, Japan. Vaccines. 2023. 11. 5
Hiroshi Okuda, Ryo Miyamoto, Satoshi Takahashi, Takeshi Kawamura, Juri Ichikawa, Ibuki Harada, Tomohiko Tamura, Akihiko Yokoyama. RNA-binding proteins of KHDRBS and IGF2BP families control the oncogenic activity of MLL-AF4. Nature Communications. 2022. 13. 1
Satoru Shinriki, Mayumi Hirayama, Akiko Nagamachi, Akihiko Yokoyama, Takeshi Kawamura, Akinori Kanai, Hidehiko Kawai, Junichi Iwakiri, Rin Liu, Manabu Maeshiro, et al. DDX41 coordinates RNA splicing and transcriptional elongation to prevent DNA replication stress in hematopoietic cells. Leukemia. 2022
Hiroki Takahashi, Ge Yang, Takeshi Yoneshiro, Yohei Abe, Ryo Ito, Chaoran Yang, Junna Nakazono, Mayumi Okamoto-Katsuyama, Aoi Uchida, Makoto Arai, et al. MYPT1-PP1β phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis. Nature communications. 2022. 13. 1. 5715-5715
川村猛, 中村有子, 近岡洋子, 中山綾, 福田暁子, 紅露拓, 辻嘉代子, WEI Feifei, 長岡孝治, 田中浩揮, et al. Neoantigen discovery by immunopeptidomics for mRNA cancer vaccines. 日本プロテオーム学会大会プログラム・抄録集. 2024. 2024 (Web)
山次健三, 高橋和希, 加藤洋人, 山下雄史, 安藝翔, 巽俊文, 金子雄大, 川村猛, 三浦麻衣, 石井正純, et al. Antibody-Mimetic Drug Conjugate: AMDC comprised of modified streptavidin and bisiminobiotin, and its use in near-infrared phototherapy. メディシナルケミストリーシンポジウム講演要旨集. 2022. 39th (CD-ROM)
高橋和希, 山次健三, 加藤洋人, 山下雄史, 安藝翔, 巽俊文, 金子雄大, 川村猛, 川村猛, 三浦麻衣, et al. Near-infrared Phototherapy Using Modified Streptavidin-iminobiotin Drug Delivery System. 日本薬学会年会要旨集(Web). 2022. 142nd
The Japanese Radiation Research Society
, 日本オミックス医療学会
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, THE MASS SPECTROMETRY SOCIETY OF JAPAN
, THE JAPANESE BIOCHEMICAL SOCIETY
, Japanese Proteomics Society