Rchr
J-GLOBAL ID：201801011881970821
Update date: Apr. 02, 2024
Matsuzaki Hirokazu
マツザキ ヒロカズ | Matsuzaki Hirokazu
Affiliation and department：
Job title：
Assistant Professor
Research field (1)：
Pharmacology
Research keywords (2)：
神経薬理
, 行動薬理
Research theme for competitive and other funds (7)：
- 2021 - 2024 うつ様症状に対するクルクミン誘導体CUD003の予防・改善効果に関する基礎研究
- 2020 - 2023 Fundamental research of antitumor activity of arsenic compound in combination with active bufadienolide compounds against glioblastoma cells
- 2019 - 2023 フェルラ酸誘導体FAD012は虚血性脳血管障害に対する予防的治療薬となり得るか?
- 2017 - 2020 Involvement of serotonergic system in the antidepressant-like effect of a novel curcumin derivative CUD003
- 2016 - 2019 Protective mechanism of FAD012, a ferulic acid derivative, against ischemic brain injury.
- 2013 - 2016 Preventive effects of novel ferulic acid derivatives on cerebral ischemia-induced swallowing dysfunction
- 2010 - 2012 Preventive effects of nitrate against ischemic brain injury
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Papers (14)：
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Takashi Asano, Meiyan Xuan, Naohiro Iwata, Jun Takayama, Kousuke Hayashi, Yosuke Kato, Toshiya Aoyama, Hiroshi Sugo, Hirokazu Matsuzaki, Bo Yuan, et al. Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats. International journal of molecular sciences. 2023. 24. 11
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Bo Yuan, Jingmei Li, Shin-Ich Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Takeshi Sakamoto, et al. Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87. Molecules (Basel, Switzerland). 2022. 27. 19
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Kaho Ogawa, Masaki Uchida, Tsutomu Yamaki, Hirokazu Matsuzaki, Mitsutoshi Kimura, Mari Okazaki, Hiroyuki Uchida, Hideshi Natsume. Delivery of acetaminophen to the central nervous system and the pharmacological effect after intranasal administration with a mucoadhesive agent and absorption enhancer. International journal of pharmaceutics. 2021. 594. 120046-120046
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Kohei Kawabata, Hirokazu Matsuzaki, Sahoko Nukui, Mari Okazaki, Ayako Sakai, Yoichi Kawashima, Naomi Kudo. Perfluorododecanoic Acid Induces Cognitive Deficit in Adult Rats. Toxicological sciences : an official journal of the Society of Toxicology. 2017. 157. 2. 421-428
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Takashi Asano, Hirokazu Matsuzaki, Naohiro Iwata, Meiyan Xuan, Shinya Kamiuchi, Yasuhide Hibino, Takeshi Sakamoto, Mari Okazaki. Protective Effects of Ferulic Acid against Chronic Cerebral Hypoperfusion-Induced Swallowing Dysfunction in Rats. International journal of molecular sciences. 2017. 18. 3
ｍore...
MISC (3)：
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Hirokazu Matsuzaki, Takeshi Izumi, Machiko Matsumoto, Taku Yamaguchi, Takayuki Yoshida, Takahiro Horinouchi, Shuken Boku. Early postnatal stress affects the hippocampal postsynaptic 5-HT1A receptor function in context-dependent conditioned fear in adult rats. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 178P-178P
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Takeshi Izumi, Takeshi Inoue, Kotaro Konno, Hirokazu Matsuzaki, Takayuki Yoshida, Taku Yamaguchi, Masahiko Watanabe, Tsukasa Koyama, Mitsuhiro Yoshioka. Characterization and functional meaning of the conditioned fear-related neural cells in the basolateral amygdala. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2009. 109. 57P-57P
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Chika Judo, Machiko Matsumoto, Riki Hirata, Hirokazu Matsuzaki, Taku Yamaguchi, Takeshi Izumi, Mitsuhiro Yoshioka, Hiroko Togashi. Functional correlates between the stress-induced synaptic response and anxiety-related behavior in early postnatal stressed male and female rats. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2009. 109. 132P-132P
Patents (3)：
Books (1)：
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Translational Methods for PTSD Research
Springer 2023 ISBN:9781071632185
Lectures and oral presentations (69)：
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新規クルクミン誘導体CUD003の抗うつ薬としての可能性
(第96回日本薬理学会年会 2022)
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スコポラミン誘発学習障害ラットにおけるクルクミン誘導体CUD003の改善効果
(第95回日本薬理学会年会 2022)
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新規クルクミン誘導体CUD003は脳虚血再灌流ラットの脳障害を抗炎症作用を介して軽減する
(第94回日本薬理学会年会 2021)
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新規クルクミン誘導体CUD003の抗うつ様効果におけるセロトニン神経系の関与
(第93回日本薬理学会年会 2020)
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新規フェルラ酸誘導体のフリーラジカル消去能及び細胞保護作用の評価
(日本薬学会第139年会)
ｍore...
Education (3)：
- 2006 - 2010 Hokkaido University Graduate School, Division of Medicine
- 2004 - 2006 Health Sciences University of Hokkaido Graduate School, Division of Pharmaceutical Sciences
- - 2004 Health Sciences University of Hokkaido Faculty of Pharmaceutical Science
Professional career (3)：
- 博士(医学) (北海道大学)
- 修士(薬学) (北海道医療大学)
- 学士(薬学) (北海道医療大学)
Work history (2)：
- 2018/04 - 現在 Josai University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences Assistant Professor
- 2010/04 - 2018/03 Josai University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences Research Assistant
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