Rchr
J-GLOBAL ID：201801012013662203
Update date: Apr. 16, 2024
mayumi Nagashimada
ナガシマダ マユミ | mayumi Nagashimada
Affiliation and department：
Research field (3)：
Molecular biology
, Metabolism and endocrinology
, Nutrition and health science
Research theme for competitive and other funds (4)：
- 2022 - 2026 運動と非アルコール性脂肪肝炎の改善をつなぐ制御分子機構の解明
- 2019 - 2022 Elucidation of the function of novel transcription factor that lead to polarization of M2 macrophages and development of metabolic disease drug discovery
- 2015 - 2019 Elucidating novel regulatory mechanisms of carotenoids with spontaneous metabolic syndrome models
- 2013 - 2015 Role of fractalkine-CX3CR1for regulation of insulin resistance
Papers (35)：
-
Suratsawadee Promsuwan, Kazuki Sawamoto, Liang Xu, Mayumi Nagashimada, Naoto Nagata, Yumi Takiyama. A natural Nrf2 activator glucoraphanin improves hepatic steatosis in high-fat diet-induced obese male mice associated with AMPK activation. Diabetology International. 2023
-
Yinhua Ni, Fen Zhuge, Liyang Ni, Naoto Nagata, Tatsuya Yamashita, Naofumi Mukaida, Shuichi Kaneko, Tsuguhito Ota, Mayumi Nagashimada. CX3CL1/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1/M2 status. Metabolism: clinical and experimental. 2022. 136. 155272-155272
-
Liang Xu, Yongping Chen, Mayumi Nagashimada, Yinhua Ni, Fen Zhuge, Guanliang Chen, Haoran Li, Tongtong Pan, Tatsuya Yamashita, Naofumi Mukaida, et al. CC chemokine ligand 3 deficiency ameliorates diet-induced steatohepatitis by regulating liver macrophage recruitment and M1/M2 status in mice. Metabolism: clinical and experimental. 2021. 125. 154914-154914
-
Toshihiro Uesaka, Mitsumasa Okamoto, Mayumi Nagashimada, Yoshihiro Tsuda, Miho Kihara, Hiroshi Kiyonari, Hideki Enomoto. Enhanced enteric neurogenesis by Schwann cell precursors in mouse models of Hirschsprung disease. Glia. 2021. 69. 11. 2575-2590
-
Mayumi Nagashimada, Masao Honda. Effect of Microbiome on Non-Alcoholic Fatty Liver Disease and the Role of Probiotics, Prebiotics, and Biogenics. International journal of molecular sciences. 2021. 22. 15
ｍore...
MISC (1)：
-
Mayumi Nagashimada, Yinhua Ni, Kazuki Sawamoto, Tsuguhito Ota. Fractalkine-CX3CR1 Signaling Deficiency Exacerbates Obesity-Induced Inflammation and Insulin Resistance. DIABETES. 2017. 66. A50-A50
Lectures and oral presentations (21)：
-
CCL3/MIP-1αの欠損は、肥満による慢性炎症を減弱しインスリン抵抗性を抑制する
(第63回日本糖尿病学会年次学術集会)
-
Lycopene alleviates obesity-induced inflammation and insulin resistance by polarizing M2 macrophages
(第40回日本肥満学会 2019)
-
肥満により減弱するFractalkine-CX3CR1シグナルの回復は、インスリン抵抗性を改善する
(第62回日本糖尿病学会年次学術集会 2019)
-
Loss of fractalkine-CX3CR1 signaling promotes diet-induced adipose tissue inflammation and insulin resistance by controlling the M1/M2 status of macrophage.
(54th European Association for the Study of Diabetes (EASD) Annual Meeting 2018)
-
Fractalkine-CX3CR1 シグナルの欠損は脂肪組織のマクロファージをM1優位にシフトさせ、インスリン抵抗性を増悪させる
(第61回日本糖尿病学会年次学術集会 2018)
ｍore...
Association Membership(s) (4)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, JAPAN SOCIETY FOR THE STUDY OF OBESITY
, 日本肝臓学会
, 糖尿病学会
