Rchr
J-GLOBAL ID：201801012446455377
Update date: Feb. 14, 2024
TOMISHIGE Michio
トミシゲ ミチオ | TOMISHIGE Michio
Affiliation and department：
Job title：
Professor
Research field (3)：
Semiconductors, optical and atomic physics
, Bio-, chemical, and soft-matter physics
, Biophysics
Research keywords (3)：
Intracellular transport
, Molecular motor
, Single molecule observation
Research theme for competitive and other funds (10)：
- 2022 - 2024 High-speed single-molecule observation of the effect of fluctuation on the coordinated motion of kinesin-1
- 2020 - 2022 High-speed single molecule observation of the ratchet mechanism of molecular motor kinesin
- 2017 - 2020 High temporal resolution single-molecule analysis of the mechanochemical coupling of kinesin
- 2016 - 2018 Single-molecule fluorescence detection of kinesin and ATP using nanotracks
- 2012 - 2015 Head-head coordination mechanism of kinesin during processive motility
- 2010 - 2011 一分子FRET法による分子モータータンパク質の動的複合体形成過程の観察
- 2009 - 2011 Single molecule FRET study for the walking mechanism of molecular motor kinesin
- 2009 - 2010 輸送分子モーターを連結したシステムの一分子観察
- 2006 - 2008 Energy transduction mechanism of kinesin as studied by simultaneous single molecule measurement of conformational change and force production
- 2004 - 2008 Regulation mechanism of the intracellular transport by kinesin
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Papers (28)：
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Noriyuki Uchida, Ai Kohata, Kou Okuro, Annalisa Cardellini, Chiara Lionello, Eric A. Zizzi, Marco A. Deriu, Giovanni M. Pavan, Michio Tomishige, Takaaki Hikima, et al. Reconstitution of microtubule into GTP-responsive nanocapsules. Nature Communications. 2022. 13. 1
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Takayuki Ariga, Keito Tateishi, Michio Tomishige, Daisuke Mizuno. Noise-Induced Acceleration of Single Molecule Kinesin-1. Physical review letters. 2021. 127. 17. 178101-178101
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Takayuki Ariga, Michio Tomishige, Daisuke Mizuno. Experimental and theoretical energetics of walking molecular motors under fluctuating environments. Biophysical Reviews. 2020
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有賀 隆行, 富重 道雄, 水野 大介. 生体分子モーター・キネシンの“散逸”を計測する. 生物物理. 2019. 59. 6. 300-304
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Kazuya Fujimoto, Yuki Morita, Ryota Iino, Michio Tomishige, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Simultaneous Observation of Kinesin-Driven Microtubule Motility and Binding of Adenosine Triphosphate Using Linear Zero-Mode Waveguides. ACS nano. 2018. 12. 12. 11975-11985
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MISC (8)：
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Takayuki Ariga, Michio Tomishige, Daisuke Mizuno. Nonequilibrium Energetics of Single Molecule Motor, Kinesin-1. BIOPHYSICAL JOURNAL. 2018. 114. 3. 509A-509A
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Yuki Morita, Kazuya Fujimoto, Ryota Iino, Michio Tomishige, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Single-molecule Fluorescence Imaging of Kinesin Using Linear Zero-Mode Waveguides. 2016 IEEE SENSORS. 2016
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TOMISHIGE M., SAKO Y., KUSUMI A. Regulation of band 3 diffusion by dissociation-association equilibrium of the erythrocyte membrane skeleton. Biophysics. 1997. 37. S195
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TOMISHIGE M, SAKO Y, KUSUMI A. Interaction between the erythrocyte membrane skeleton and the integral membrane protein band 3 as studied by optical tweezers. Biophysics. 1997. 37. S75
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富重 道雄, 楠見 明弘. 生細胞研究のためのナノテクノロジ---光ピンセットとナノ計測. 生体の科学. 1997. 48. 4. 313-318
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Education (3)：
- 1995 - 1998 The University of Tokyo Graduate School, Division of General Culture
- 1993 - 1995 The University of Tokyo Graduate School, Division of General Culture
- 1987 - 1993 The University of Tokyo Faculty of Liberal Arts
Professional career (1)：
Work history (7)：
- 2021/04 - 現在 Aoyama Gakuin University College of Science and Engineering Department of Physical Sciences Professor
- 2017/04 - 2021/03 Aoyama Gakuin University College of Science and Engineering Department of Physics and Mathematics Professor
- 2003/06 - 2017/03 Associate Professor
- 2003/06 - 2017/03 Associate Professor
- 1999/04 - 2003/05 Researcher
- 1998/11 - 1999/03 Special researcher of the Japan Society for the Promotion of Science
- 1998/04 - 1998/10 Special researcher of the Japan Society for the Promotion of Science
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Association Membership(s) (2)：
Biophysical Society
, Biophysical Society of Japan
