TOMISHIGE Michio

トミシゲミチオ | TOMISHIGE Michio

Affiliation and department：
Job title： Professor

Research field (3)： Semiconductors, optical and atomic physics , Bio-, chemical, and soft-matter physics , Biophysics

Research keywords (3)： Intracellular transport , Molecular motor , Single molecule observation

Research theme for competitive and other funds (10)：

2022 - 2024 High-speed single-molecule observation of the effect of fluctuation on the coordinated motion of kinesin-1
2020 - 2022 High-speed single molecule observation of the ratchet mechanism of molecular motor kinesin
2017 - 2020 High temporal resolution single-molecule analysis of the mechanochemical coupling of kinesin
2016 - 2018 Single-molecule fluorescence detection of kinesin and ATP using nanotracks
2012 - 2015 Head-head coordination mechanism of kinesin during processive motility

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Papers (34)：

Yamato Niitani, Kohei Matsuzaki, Erik Jonsson, Ronald D. Vale, Michio Tomishige. Kinetic regulation of kinesin's two motor domains coordinates its stepping along microtubules. 2024
Tsukasa Makino, Ryo Kanada, Teppei Mori, Ken-ichi Miyazono, Yuta Komori, Haruaki Yanagisawa, Shoji Takada, Masaru Tanokura, Masahide Kikkawa, Michio Tomishige. Tension-induced suppression of allosteric conformational changes explains coordinated stepping of kinesin-1. 2024
Takayuki ARIGA, Keito TATEISHI, Michio TOMISHIGE, Daisuke MIZUNO. Nonthermal Fluctuation Accelerates Molecular Motor Kinesin. 2023. 63. 2. 86-90
Noriyuki Uchida, Ai Kohata, Kou Okuro, Annalisa Cardellini, Chiara Lionello, Eric A. Zizzi, Marco A. Deriu, Giovanni M. Pavan, Michio Tomishige, Takaaki Hikima, et al. Reconstitution of microtubule into GTP-responsive nanocapsules. Nature Communications. 2022. 13. 1
Takayuki Ariga, Keito Tateishi, Michio Tomishige, Daisuke Mizuno. Noise-Induced Acceleration of Single Molecule Kinesin-1. Physical review letters. 2021. 127. 17. 178101-178101

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MISC (9)：

Takayuki Ariga, Michio Tomishige, Daisuke Mizuno. Nonequilibrium Energetics of Single Molecule Motor, Kinesin-1. BIOPHYSICAL JOURNAL. 2018. 114. 3. 509A-509A
Yuki Morita, Kazuya Fujimoto, Ryota Iino, Michio Tomishige, Hirofumi Shintaku, Hidetoshi Kotera, Ryuji Yokokawa. Single-molecule Fluorescence Imaging of Kinesin Using Linear Zero-Mode Waveguides. 2016 IEEE SENSORS. 2016
Kanada Ryo, Makino Tsukasa, Tomishige Michio, Takada Shoji. 1PS037 The effect of the internal tension between two heads on the nucleotide binding site of kinesin-1 studied by All-atom MD(The 50th Annual Meeting of the Biophysical Society of Japan). Seibutsu Butsuri. 2012. 52. S80
TOMISHIGE M., SAKO Y., KUSUMI A. Regulation of band 3 diffusion by dissociation-association equilibrium of the erythrocyte membrane skeleton. Biophysics. 1997. 37. S195
TOMISHIGE M, SAKO Y, KUSUMI A. Interaction between the erythrocyte membrane skeleton and the integral membrane protein band 3 as studied by optical tweezers. Biophysics. 1997. 37. S75

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Education (3)：

1995 - 1998 The University of Tokyo Graduate School, Division of General Culture
1993 - 1995 The University of Tokyo Graduate School, Division of General Culture
1987 - 1993 The University of Tokyo Faculty of Liberal Arts

Professional career (1)：

Work history (7)：

2021/04 - 現在 Aoyama Gakuin University College of Science and Engineering Department of Physical Sciences Professor
2017/04 - 2021/03 Aoyama Gakuin University College of Science and Engineering Department of Physics and Mathematics Professor
2003/06 - 2017/03 Associate Professor
2003/06 - 2017/03 Associate Professor
1999/04 - 2003/05 Researcher

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Association Membership(s) (2)：

Biophysical Society , Biophysical Society of Japan

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