Haraguchi Tokuko

ハラグチトクコ | Haraguchi Tokuko

Affiliation and department：
Job title：特任教授
Other affiliations (2)：

Homepage URL (1)： https://www.fbs.osaka-u.ac.jp/labs/hiraoka/index.html

Research field (3)： Cell biology , Genetics , Molecular biology

Research keywords (11)：染色体核内配置 , 染色体構造 , 遺伝子・デリバリー , バイオイメージング , 細胞核構造 , 核膜 , テトラヒメナ , 分裂酵母 , mammalian cell , Live cell imaging , Cell Biology

Research theme for competitive and other funds (13)：

2018 - 2023 -
2017 - 2020 The function of the nuclear pore complex during the nuclear differentiation in Tetrahymena
2017 - 2019 Mechanisms of nuclear entry of transfected exogenous DNAs
2015 - 2018 International research network for chromatin structure, dynamics, and function
2013 - 2018 Chromatin structure, dynamics, and function

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Papers (251)：

Haruhiko Asakawa, Koji Nagao, Tatsuo Fukagawa, Chikashi Obuse, Yasushi Hiraoka, Tokuko Haraguchi. Interaction mapping between nucleoporins in the fission yeast Schizosaccharomyces pombe using mass-spectrometry. The Journal of Biochemistry. 2024
Yasuhiro Hirano, Tsukino Sato, Ayane Miura, Yoshino Kubota, Tomoko Shindo, Koichi Fukase, Tatsuo Fukagawa, Kazuya Kabayama, Tokuko Haraguchi, Yasushi Hiraoka. Disordered region of nuclear membrane protein Bqt4 recruits phosphatidic acid to the nuclear envelope to maintain its structural integrity. The Journal of biological chemistry. 2024. 107430-107430
Nao Yonezawa, Tomoko Shindo, Haruka Oda, Hiroshi Kimura, Yasushi Hiraoka, Tokuko Haraguchi, Kazuo Yamagata. Reconstruction of artificial nuclei with nuclear import activity in living mouse oocytes. 2024
Yoko Hayashi-Takanaka, Ichiro Hiratani, Tokuko Haraguchi, Yasushi Hiraoka. Proteasome-dependent Orc6 removal from chromatin upon S-phase entry safeguards against MCM reloading and tetraploidy. 2024
Yasuhiro Hirano, Tsukino Sato, Ayane Miura, Yoshino Kubota, Tomoko Shindo, Koichi Fukase, Tatsuo Fukagawa, Kazuya Kabayama, Tokuko Haraguchi, Yasushi Hiraoka. Nuclear membrane protein Bqt4 maintains nuclear envelope integrity by recruiting phosphatidic acid. 2023

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MISC (172)：

平野泰弘, 佐藤つきの, 三浦彩音, 深瀬浩一, 深川竜郎, 樺山一哉, 原口徳子, 平岡泰. 核膜タンパク質Bqt4はホスファチジン酸との結合を介して核膜の恒常性維持を担う. 日本生化学会大会(Web). 2023. 96th
平野泰弘, 佐藤つきの, 三浦彩音, 樺山一哉, 樺山一哉, 深瀬浩一, 深瀬浩一, 深川竜郎, 原口徳子, 平岡泰. Roles of the lipid-binding region of an inner nuclear membrane protein Bqt4 in fission yeast. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
淺川東彦, 大槻千鶴, 長尾恒治, 信藤知子, 芝田晋介, 小布施力史, 平岡泰, 原口徳子. Interaction of Sec13 with Nup96 is dispensable for the nuclear pore complexes in the fission yeast Schizosaccharomyces pombe. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
Construction of artificial nuclei in mouse embryos. 2020. 52. 6. 292-299
淺川東彦, 糀谷知子, 糀谷知子, 松田厚志, 楊惠如, 楊惠如, 大槻千鶴, 小坂田裕子, 岩本政明, 岩本政明, et al. 分裂酵母に特異的な核膜孔複合体アウターリングの非対称性局在. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd

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Patents (5)：

Books (6)：

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Lectures and oral presentations (41)：

微小核の核膜形成とインポート活性の有無はサイズに依存する
(第42回日本分子生物学会年会 2019)
転写能を持つ人工細胞核の作製
(第2回クロマチン潜在能領域会議 2019)
DNAビーズを用いた未受精卵内でのキネトコアの再構成
(第41回日本分子生物学会年会 2018)
ライブセルイメージングを用いたマウス受精卵におけるDNA損傷の可視化及び定量化
(第41回日本分子生物学会年会 2018)
DNAビーズを用いたマウス受精卵での核構築
(第41回日本分子生物学会年会 2018)

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Professional career (1)：

Awards (1)：

2021/02 - Ochanomizu University Ochanomizu University Award, The 5th Kono Yasui Prize

Association Membership(s) (4)：

遺伝子・デリバリー研究会 , The Biophysical Society of Japan , The Molecular Biology Society of Japan , Japanese Society for Cell Biology

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