Komiyama Hiromitsu

Research theme for competitive and other funds (22)：

2018 - 2021 Search for new biomarkers for mesenchymal circulating tumor cells using next-generation TelomeScan
2018 - 2021 CAGE発現解析を用いた大腸がん肺転移予測マーカーの特定
2017 - 2021 Identification of biomaker for predicting liver metastasis of colorectal cancer with CAGE analysis
2017 - 2021 新テロメスキャンF35による大腸がんCTCの臨床応用と機能分析
2016 - 2020 Development of the detection method of curculating tumour cells (CTCs) which act as a sensitive marker for colorectal cancer using new microfluidic CTC chip

2016 - 2020 Development of CAR-T therapy targeting amino acid transporter SLC7A1 against colorectal cancer

2016 - 2020 Development of biomarker for detection of lymphnode metastasis and prediction of recurrence in colorectal cancer using CAGE analysis

2016 - 2020 Development of circulating tumor DNA as a novel tumor marker for uterine cancer

2016 - 2020 Elucidation of the colon cancer cell cluster formation mechanism and application to novel anti-cancer metastasis treatment

2016 - 2019 Dissection of molecular mechanisms of the metastatic niche dormancy and application to the ant-metastatic therapy

2015 - 2019 Searching for miRNA as a biomarker in blood colorectal cancer in blood to evaluate sensitivities against chemotherapies for colorectal cancer

2015 - 2019 Construction of personalized monitoring system for colorectal caner using circulating tumor DNA

2017 - 2019 CAGE発現解析を用いた大腸がん肝転移予測マーカーの同定

2015 - 2018 The analysis of circulating tumor cell measurement of lung cancer by next genaration TelomeScan

2015 - 2018 Isolation and functional analysis of blood circulating breast cancer cells by improved telome scan

2014 - 2018 Isolation and functional analysis of blood circulating tumor cells in colorectal cancer using modified Telomescan system for clinical application

2014 - 2017 Identification of biomarker for colorectal cancer metastasis to lung with CAGE analyses

2013 - 2016 Function analysis of circulating tumor cells using a microfluid chip for colorectal cancer.

2013 - 2016 Studies in the action mechanism of fibrinolytic system on the inflammatory bowel disease and its clinical applications

2013 - 2016 Identification of novel biomarkers predicting lymph node and liver metastases colorectal cancer with CAGE analysis

2012 - 2015 Blocking fibrinolytic system in mice reduces colorectal carcinogenesis associated with chronic colitis.

2011 - 2012 Plasmin inhibition protects against dextran sulfate sodium-induced colitis

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Papers (62)：

河合雅也, 百瀬裕隆, 塚本亮一, 呉一眞, 本庄薫平, 盧尚志, 岡澤裕, 高橋里奈, 河野眞吾, 宗像慎也, et al. 直腸癌手術におけるDiverting stomaの意義. 日本外科学会定期学術集会抄録集. 2021. 121回. SF-6
Shinya Munakata, Takae Ueyama, Haruna Ishihara, Hiromitsu Komiyama, Ryoichi Tsukamoto, Masaya Kawai, Makoto Takahashi, Yutaka Kojima, Yuichi Tomiki, Kazuhiro Sakamoto. Angiopoietin-2 as a Prognostic Factor in Patients with Incurable Stage IV Colorectal Cancer. JOURNAL OF GASTROINTESTINAL CANCER. 2021. 52. 1. 237-242
RYOSUKE ICHIKAWA, KIICHI SUGIMOTO, KAZUMASA KURE, KUMPEI HONJO, RINA TAKAHASHI, YU OKAZAWA, MASAYA KAWAI, SHINYA MUNAKATA, SHUN ISHIYAMA, HIROMITSU KOMIYAMA, et al. Usefulness of an IL-6 Semi-Quantification Kit in Patients with Perforative Peritonitis. Juntendo Medical Journal. 2021. 67. 2. 158-164
RYOICHI TSUKAMOTO, MASAKI HOSOYA, MIDORI FUKAYA, NORIHIKO YOKOYAMA, SHINGO KAWANO, KIICHI SUGIMOTO, MAKOTO TAKAHASHI, KAZUHIRO SAKAMOTO, HIROMITSU KOMIYAMA. Identification of MicroRNA 15b-3p as a Diagnostic Marker for Early Stage of Colorectal Cancer Through Comprehensive RNA Analysis. Juntendo Medical Journal. 2021. 67. 3. 272-281
Kazumasa Kure, Masaki Hosoya, Takae Ueyama, Midori Fukaya, Kiichi Sugimoto, Yuichi Tomiki, Takashi Ohnaga, Kazuhiro Sakamoto, Hiromitsu Komiyama. Using the polymeric circulating tumor cell chip to capture circulating tumor cells in blood samples of patients with colorectal cancer. ONCOLOGY LETTERS. 2020. 19. 3. 2286-2294

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MISC (328)：

本庄薫平, 河野眞吾, 盧尚志, 呉一眞, 高橋里奈, 岡澤裕, 水越幸輔, 河合雅也, 宗像慎也, 石山隼, et al. 直腸NETに対する内視鏡治療"ESD with myectomy". 日本大腸肛門病学会雑誌. 2021. 74. 2. 112-112
小針文, 土谷祐樹, 呉一眞, 本庄薫平, 高橋里奈, 岡澤裕, 河合雅也, 宗像慎也, 杉本起一, 小見山博光, et al. 巨大な粘液分泌を伴う直腸LSTに対し腹腔鏡下腹会陰式直腸切断術を施行した一例. 日本外科系連合学会誌. 2020. 45. 5. 656-656
深谷緑, 呉一眞, 大永崇, 細谷理樹, 杉本起一, 坂本一博, 小見山博光. 大腸癌患者血液検体からの流体CTCチップを用いた循環腫瘍細胞検出. 日本癌学会総会記事. 2020. 79回. PJ15-4
坂本一博, 百瀬裕隆, 萩原俊昭, 松澤宏和, 盧尚志, 呉一眞, 本庄薫平, 石山隼, 杉本起一, 小見山博光, et al. 局所進行結腸癌に対する腹腔鏡手術の検討. 日本内視鏡外科学会雑誌. 2019. 24. 7. SF022-6
塚本亮一, 小見山博光, 河野眞吾, 河合雅也, 高橋玄, 小島豊, 冨木裕一, 坂本一博. 網羅的解析を用いた新規結腸癌診断マーカーの探索. 日本癌治療学会学術集会抄録集. 2019. 57回. P16-4

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Patents (2)：

Work history (2)：

2016/04 - 現在 Juntendo University Faculty of Medicine
2012/04 - 2016/03 Juntendo University Faculty of Medicine

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