Research field (3):
Clinical pharmacy
, Physiology
, Pharmacology
Research theme for competitive and other funds (16):
2024 - 2027 Progression of cardiovascular disease facilitated by masticatory dysfunction: Molecular basis and novel therapeutic strategies through inter-organ communication
2023 - 2025 新規モデル動物を用いた骨格筋におけるリアノジン受容体CICR機構の意義
2022 - 2025 Trans-scale thermal signaling in muscle
2013 - 2016 Functional role of NO-induced Ca2+ release in skeletal muscle
2009 - 2014 Imaging analyses of signaling mechanism in central nervous system cell-cell network
2004 - 2005 Role of membrane potential -dependent modulation of the intracellular Ca^<2+> stores
2000 - 2004 細胞内シグナルフローの可視化解析
2001 - 2002 消化管における自発収縮機構の解明
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Papers (61):
Takashi Murayama, Yuya Otori, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Takashi Sakurai, Haruo Ogawa. Dual role of the S5 segment in type 1 ryanodine receptor channel gating. Communications Biology. 2024. 7. 1
Madoka Suzuki, Chujie Liu, Kotaro Oyama, Toshiko Yamazawa. Trans-scale thermal signaling in biological systems. The Journal of Biochemistry. 2023
Madoka Suzuki, Kotaro Oyama, Toshiko Yamazawa. Hybrid Biophysics: Interdisciplinary approaches for trans-scale analysis of organism-environment interactions. Biophysics and Physicobiology. 2023
Yoshitaka Tsuboi, Kotaro Oyama, Fuyu Kobirumaki-Shimozawa, Takashi Murayama, Nagomi Kurebayashi, Toshiaki Tachibana, Yoshinobu Manome, Emi Kikuchi, Satoru Noguchi, Takayoshi Inoue, et al. Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca2+ dynamics in primary skeletal myocytes. Journal of General Physiology. 2022. 154. 11
Kotaro Oyama#, Vadim Zeeb#, Toshiko Yamazawa#, Nagomi Kurebayashi, Fuyu Kobirumaki-Shimozawa, Takashi Murayama, Hideto Oyamada, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, et al. Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating. Proceedings of the National Academy of Sciences. 2022. 119. 32
Takashi Murayama, Toshiko Yamazawa, Takuya Kobayashi, Nagomi Kurebayashi, Satoru Noguchi, Ichizo Nishino, Shuichi Mori, Hiroyuki Kagechika, Jose R. Lopez, Paul D. Allen. Therapeutic Effects of a Novel RyR1 Inhibitor on Malignant Hyperthermia-Susceptible Model Mice. BIOPHYSICAL JOURNAL. 2020. 118. 3. 98A-98A
THE JAPANESE SOCIETY OF PHYSICAL FITNESS AND SPORTS MEDICINE
, THE BIOPHYSICAL SOCIETY OF JAPAN
, THE PHYSIOLOGICAL SOCIETY OF JAPAN
, THE JAPANESE PHARMACOLOGICAL SOCIETY