Iijima Koichi

イイジマコウイチ | Iijima Koichi

Affiliation and department：

Research field (2)： Neuropathology , Neuroscience - general

Research keywords (3)： Dementia・Alzheimer's disease , Neuroscience , Genetics

Research theme for competitive and other funds (6)：

2022 - 2026 神経血管ユニットを構成するグリア終足分子のアルツハイマー病病理形成における役割
2022 - 2025 脳の浄化機能を司るグリア細胞の貪食活性を制御するアミノ酸の同定と健康寿命の増進
2020 - 2023 Roles of reactive astrocyte in AD pathogenesis
2020 - 2022 The effects of dietary restriction on age-related decline in glial engulfment
2016 - 2019 Roles of glial innate immunity in age-related neurodegeneration

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Papers (61)：

Michiko Sekiya, Yasufumi Sakakibara, Yu Hirota, Naoki Ito, Sachie Chikamatsu, Kimi Takei, Risa Nishijima, Koichi M. Iijima. Decreased plasma nicotinamide and altered NAD+ metabolism in glial cells surrounding Aβ plaques in a mouse model of Alzheimer's disease. Neurobiology of Disease. 2024. 106694-106694
Kanako Shinno, Yuri Miura, Koichi M. Iijima, Emiko Suzuki, Kanae Ando. Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β. 2024
Akiko Maruko, Koichi M Iijima, Kanae Ando. Dissecting the daily feeding pattern: Peripheral CLOCK/CYCLE generate the feeding/fasting episodes and neuronal molecular clocks synchronize them. iScience. 2023. 26. 11. 108164-108164
Yu Hirota, Yasufumi Sakakibara, Kimi Takei, Risa Nishijima, Michiko Sekiya, Koichi M Iijima. Alzheimer's Disease-Related Phospho-Tau181 Signals Are Localized to Demyelinated Axons of Parvalbumin-Positive GABAergic Interneurons in an App Knock-In Mouse Model of Amyloid-β Pathology. Journal of Alzheimer's disease : JAD. 2023
Yasufumi Sakakibara, Risa Yamashiro, Sachie Chikamatsu, Yu Hirota, Yoko Tsubokawa, Risa Nishijima, Kimi Takei, Michiko Sekiya, Koichi M Iijima. Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration. iScience. 2023. 26. 2. 105968-105968

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MISC (32)：

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Education (3)：

1998 - 2001 The University of Tokyo Faculty of Pharmaceutical Sciences Graduate School of Pharmaceutical Sciences PhD course
1996 - 1998 The University of Tokyo Faculty of Pharmaceutical Sciences Graduate School of Pharmaceutical Sciences Master course
1992 - 1996 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy

Work history (6)：

2021/04 - 現在 National Center for Geriatrics and Gerontrogy Department of Neurogenetics Professor
2018/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences Department of Experimental Gerontology Visiting Professor
2018/10 - 2021/03 National Center for Geriatrics and Gerontology Department of Alzheimer's Disease Research Department Head
2013/09 - 2018/09 National Center for Geriatrics and Gerontology Department of Alzheimer's Disease Research Section Chief
2006/09 - 2013/08 Thomas Jefferson University Department of Neuroscience Assistant Professor

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Committee career (3)：

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