Nemoto Wataru

ネモトワタル | Nemoto Wataru

Affiliation and department：

Research field (2)： Neuroscience - general , Pharmacology

Research keywords (6)：広汎性侵害抑制調節 , neuropathy , angiotensin , Spinal cord , Diabetes , Pain

Research theme for competitive and other funds (8)：

2022 - 2025 Functional analysis of angiotensin-converting enzyme 2 in the brain and development of novel therapeutic agents for depression
2020 - 2023 Elucidation of neuropathic pain associated with type 2 diabetes mellitus: Involvement of spinal angiotensin system and development of the novel therapeutic agents
2019 - 2023 神経障害性疼痛におけるアンジオテンシン変換酵素2の役割の解明と新規治療薬の開発
2018 - 2021 Role of brain angiotensin system on animal model of depression
2017 - 2020 Elucidation of the mechanism underlying diabetic neuropathic pain and development of its new therapy: Examination from the viewpoint of spinal angiotensin system

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Papers (54)：

Osamu Nakagawasai, Kohei Takahashi, Takuto Suzuki, Ryota Yamagata, Wataru Nemoto, Koichi Tan-No. Long-term effects of a single high-dose intraperitoneal injection of lipopolysaccharide on depression-like behavior in adolescent mice. Neuroscience letters. 2024. 137989-137989
Shiori Iwane, Wataru Nemoto, Tomoyoshi Miyamoto, Tomonori Hayashi, Masayuki Tanaka, Kazuki Uchitani, Tatsuya Muranaka, Masanori Fujitani, Yuichi Koizumi, Atsushi Hirata, et al. Clinical and preclinical evidence that angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prevent diabetic peripheral neuropathy. Scientific Reports. 2024. 14. 1
Osamu Nakagawasai, Kohei Takahashi, Taisei Koyama, Ryota Yamagata, Wataru Nemoto, Koichi Tan-No. Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice. Molecular Brain. 2023. 16. 1
Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Koichi Tan-No. Angiotensin-Related Peptides and Their Role in Pain Regulation. Biology. 2023. 12. 5. 755-755
Osamu Nakagawasai, Kohei Takahashi, Wakana Sakuma, Wataru Nemoto, Ruka Kobayashi, Tomohiro Hoshi, Satoshi Matsumoto, Takeshi Tadano, Koichi Tan-No. Peptides obtained by enzymatic decomposition of mackerel induce recovery from physical fatigue by enhancing the SIRT1-mediated antioxidant effect in the soleus muscle of mice. Journal of pharmacological sciences. 2023. 152. 1. 61-67

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MISC (84)：

冨田詩織, 冨田詩織, 根本亙, 宮本朋佳, 宮本朋佳, 林友典, 田中雅幸, 打谷和記, 村中達也, 小泉祐一, et al. Effects of angiotensin converting enzyme inhibitors or receptor blockers on diabetic peripheral neuropathy: clinical evidence supported by a preclinical study. 日本薬学会年会要旨集(Web). 2023. 143rd
Wataru Nemoto, KOZAK Dalia, SOTOCINAL Susana G., TANSLEY Shannon, MOGIL Jeffrey S. Involvement of the monoaminergic nervous system in hyperalgesic and analgesic descending control of nociception. 日本薬学会年会要旨集(Web). 2023. 143rd
中川西修, 山田耕太郎, 大島有湖, 根本亙, 高橋浩平, 高橋浩平, 笹川由香, 墨田康男, 丹野孝一. Anti-fatigue preventive effect of globin digest in mice. 日本薬学会年会要旨集(Web). 2023. 143rd
中川西修, 若生美春, 小平貴代, 小野涼太郎, 高橋浩平, 高橋浩平, 根本亙, 丹野孝一. Captoprilの抗うつ作用における海馬アンジオテンシン系の関与. 日本薬理学雑誌. 2022. 157. Supplement
冨田詩織, 冨田詩織, 宮本朋佳, 宮本朋佳, 田中雅幸, 打谷和記, 小泉祐一, 村中達也, 根本亙, 丹野孝一, et al. アンギオテンシン変換酵素阻害薬とアンギオテンシンII受容体拮抗薬は糖尿病性末梢神経障害の発症を抑制する:臨床・基礎融合研究によるエビデンス. 生体機能と創薬シンポジウム要旨集. 2022. 2022

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Professional career (1)：

Work history (4)：

2023/04 - Tohoku Medical and Pharmaceutical University
2021/04 - マギル大学アランエドワードペイン研究センター客員研究員
2018/03 - Tohoku Medical and Pharmaceutical University Department of Pharmacology, Faculty of Pharmaceutical Sciences Assistant Professor
2012/04 - Tohoku Medical and Pharmaceutical University Department of Pharmacology, Faculty of Pharmaceutical Sciences Research Associate

Committee career (3)：

Awards (2)：

Association Membership(s) (5)：

THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY , 国際疼痛学会 , 日本神経化学会 , 北米神経科学会

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