Rchr
J-GLOBAL ID：201801012937289240   Update date: Jul. 17, 2024

Takahashi Jun

Takahashi Jun
Homepage URL  (1)： https://www.cira.kyoto-u.ac.jp/j/research/takahashi_summary.html
Research field  (2)： Cell biology ,  Neurosurgery
Research keywords  (2)： 神経再生 ,  脳神経外科
Research theme for competitive and other funds  (23)：
  • 2022 - 2025 Functions of IL-1B in preclinical models of RNF213-related angiopathy
  • 2019 - 2022 Identification of molecular mechanisms of RNF213-related occlusive cerebrovascular diseases and development of new treatment strategies
  • 2017 - 2020 Reconstruction of cerebrospinal pathway using iPS cells
  • 2016 - 2019 Identification of modifiers of moyamoya disease causing gene RNF213 and development of in vitro and in vivo models of the disease
  • 2013 - 2017 Transplantation of iPS cell-derived neuronal stem cells into ischemic brain
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Papers (138)：
  • Ryosuke Tsuchimochi, Keitaro Yamagami, Naoko Kubo, Naoya Amimoto, Fabian Raudzus, Bumpei Samata, Tetsuhiro Kikuchi, Daisuke Doi, Koji Yoshimoto, Aya Mihara, et al. Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain. Stem cell reports. 2023. 18. 4. 899-914
  • Hiromasa Adachi, Asuka Morizane, Sadaharu Torikoshi, Fabian Raudzus, Yukimasa Taniguchi, Susumu Miyamoto, Kiyotoshi Sekiguchi, Jun Takahashi. Pretreatment with Perlecan-Conjugated Laminin-E8 Fragment Enhances Maturation of Grafted Dopaminergic Progenitors in Parkinson’s Disease Model. Stem Cells Translational Medicine. 2022. 11. 7. 767-777
  • Luc Grinand, Jun Takahashi. Automated measurement of fluorescence signals reveals a significant increase of the graft-derived neurite extension in neonates compared to aged rats. Regenerative Therapy. 2022. 19. 97-106
  • Egawa N, Hamanaka G, K Chung, Ishikawa H, Shindo A, Maki T, Takahashi R, Inoue H, Eng H. Lo, Arai K. High Mobility Group A1 Regulates Transcription Levels of Oligodendrocyte Marker Genes in Cultured Oligodendrocyte Precursor Cells. International Journal of Molecular Sciences. 2022. 23. 4. 2236-2236
  • Satoe Hiramatsu, Asuka Morizane, Tetsuhiro Kikuchi, Daisuke Doi, Kenji Yoshida, Jun Takahashi. Cryopreservation of Induced Pluripotent Stem Cell-Derived Dopaminergic Neurospheres for Clinical Application. Journal of Parkinson's Disease. 2021. 12. 3. 871-884
ｍore...
MISC (121)：
  • 森実飛鳥, 高橋 淳. パーキンソン病に対する再生医療とリハビリテーション. 総合リハビリテーション. 2021. 49. 1. 23-28
  • 猪原 匡史, 岡崎 周平, 森本 貴昭, 鎌谷 洋一郎, 上村 鉄平, 原田 浩二, 冨田 努, 東山 綾, 高橋 淳, 中川原 譲二, et al. 日本人のアテローム血栓性脳梗塞の強力な遺伝子多型RNF213 p.4810K. 臨床神経学. 2019. 59. Suppl. S233-S233
  • Clinical application of cell therapy for Parkinson's disease. 2017. 262. 6. 677-682
  • Cell Transplantation Therapy for Parkinson's Disease. 2017. 72. 6. 868-872
  • Cell therapy for Parkinson's disease. 2017. 260. 7. 568-572
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Patents (13)：
  • ドーパミン産生神経前駆細胞の製造方法
  • 神経前駆細胞の選別方法
  • 大脳皮質ニューロンの誘導方法
  • ドーパミン産生神経前駆細胞の製造方法
  • 新規ドーパミン産生神経前駆細胞の誘導方法
ｍore...
Education (2)：
  • - 1993 京都大学大学院 医学研究科 脳神経外科学
  • - 1986 Kyoto University Faculty of Medicine
Professional career (1)：
  • 博士(医学) (京都大学)
Work history (7)：
  • 2022 - 現在 京都大学iPS細胞研究所 所長
  • 2012 - 現在 京都大学iPS細胞研究所 臨床応用研究部門 教授
  • 2007 - 2012 Kyoto University Institute for Frontier Medical Sciences
  • 2003 - 2007 Kyoto University Neurosurgery, Hospital
  • 1997 - 2003 Kyoto University Hospital, Neurosurgery
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Awards (2)：
  • 2018/03 - 一般社団法人日本再生医療学会 (JSRM) 日本再生医療学会賞(臨床部門)
  • 2005 - The Michael J. Fox Foundation for Parkinson's Research(MJFF) Cell Replacement Therapy for Parkinson's Disease Award
Association Membership(s) (5)：
THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  International Society for Stem Cell Reseach ,  日本脳神経外科コングレス ,  日本脳神経外科学会
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