Oltea Sampetrean

Affiliation and department：
Job title： Administrative Director/Project Professor

Research field (1)： Cell biology

Research keywords (3)： cellular biology , cancer stem cell , brain tumors

Research theme for competitive and other funds (9)：

2022 - 2027 Plastic regulation of chromosome dynamics in cancer
2022 - 2025 脳腫瘍幹細胞の表現型可塑性及びフェノタイプ・スイッチの実態解明と克服方法の確立
2018 - 2023 Novel and Interdisciplinary Application of Hard X-ray and Gamma-ray Detectors
2019 - 2022 Evaluation and targeting of the autonomous niche of glioma stem cells
2016 - 2019 Characterization and targeting strategies for the glioma stem cell niche

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Papers (71)：

Yoshihiro Ohtsuka, Satoshi Suehiro, Akihiro Inoue, Takanori Ohnishi, Masahiro Nishikawa, Daisuke Yamashita, Hajime Yano, Mohammed E Choudhury, Saya Ozaki, Oltea Sampetrean, et al. Berberine as a potential enhancer for 5-ALA-mediated fluorescence in glioblastoma: increasing detectability of infiltrating glioma stem cells to optimize 5-ALA-guided surgery. Journal of neurosurgery. 2024. 1-11
Masao Fukumura, Naosuke Nonoguchi, Shinji Kawabata, Ryo Hiramatsu, Gen Futamura, Koji Takeuchi, Takuya Kanemitsu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki, et al. 5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy. Scientific Reports. 2023. 13. 1
Atsushi Yagishita, Shin'ichiro Takeda, Kazunobu Ohnuki, Miho Katsuragawa, Oltea Sampetrean, Hirofumi Fujii, Tadayuki Takahashi. Dual-radionuclide in vivo imaging of micro-metastasis and lymph tract with submillimetre resolution. Scientific reports. 2023. 13. 1. 19464-19464
Ryota Tamura, Hiroyuki Miyoshi, Kent Imaizumi, Masahiro Yo, Yoshitaka Kase, Tsukika Sato, Mizuto Sato, Yukina Morimoto, Oltea Sampetrean, Jun Kohyama, et al. Gene therapy using genome-edited iPS cells for targeting malignant glioma. BIOENGINEERING & TRANSLATIONAL MEDICINE. 2022
Yuta Chonan, Tadahiro Yamashita, Oltea Sampetrean, Hideyuki Saya, Ryo Sudo. Spatial Heterogeneity of Invading Glioblastoma Cells Regulated by Paracrine Factors. Tissue Engineering Part A. 2022. 28. 13-14. 573-585

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MISC (29)：

田村亮太, 楊正博, 三好浩之, オルテアサンペトラ, 佐谷秀行, 岡野栄之, 戸田正博. Study of cell-based gene therapy for malignant glioma using genome-edited human induced pluripotent stem cells. 日本脳腫瘍学会プログラム・抄録集. 2021. 39th
齋藤潤, 齋藤潤, 大西伸幸, 杉原英志, 清水孝恒, 清水孝恒, 木村聖美, 小池直義, 小池直義, サンペトラオルテア, et al. Benzaldehydeは癌細胞のAxl受容体の発現を14-3-3ζを介して抑制し,Osimertinibによる治療抵抗性を制する. 日本癌学会学術総会抄録集(Web). 2021. 80th
木村聖美, 木村聖美, 杉原英志, 杉原英志, 山口さやか, 山口さやか, 信末博行, サンペトラオルテア, 大槻雄士, 武藤章弘, et al. 骨肉腫に対するMEK阻害療法の検証. 日本癌学会学術総会抄録集(Web). 2021. 80th
推名健太郎, 山崎淳太郎, 大槻雄士, 平田雄紀, 岡崎章悟, 土橋賢司, サンペトラ・オルテア, 光石陽一郎, 高橋史行, 高橋和久, et al. 小細胞肺癌において、xCTはがん幹細胞性に寄与する(xCT confers cancer stem-like properties in small cell lung cancer cells). 日本癌学会総会記事. 2019. 78回. E-1102
Shohei Kamenori, Kentaro Suina, Juntaro Yamasaki, Subaru Shintani, Yuji Otsuki, Yuki Hirata, Shogo Okazaki, Kenji Tsuchihashi, Oltea Sampetrean, Yoichiro Mitsuishi, et al. SLC7A11 expression confers cancer stem-like properties in small cell lung cancer cells. CANCER RESEARCH. 2019. 79. 13

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Education (2)：

2005 - 2009 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
1996 - 2002 Tokyo Medical and Dental University Faculty of Medicine School of Medicine

Work history (6)：

2024/04 - 現在 Keio University Human Biology-Microbiome-Quantum Research Center (Bio2Q) Administrative Director/Project Professor
2022/11 - 2024/06 Keio University Human Biology-Microbiome-Quantum Research Center (Bio2Q) Administrative Director
2023/07 - 2024/03 Keio University School of Medicine Department of Molecular Biology Assisstant Professor
2022/04 - 2023/06 Keio University School of Medicine Dept. of Microbiology and Immunology Assistant Professor
2018 - 2022 Keio University School of Medicine IAMR・Division of Gene Regulation Instructor

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Awards (2)：

2010 - 101 AACR meeting Highly Rated Paper
2009 - Tokyo Medical and Dental University Fukuoka Prize

Association Membership(s) (5)：

American Association for Cancer Research , THE JAPAN SOCIETY FOR NEURO-ONCOLOGY , THE JAPANESE CONGRESS OF NEUROLOGICAL SURGEONS , THE JAPAN NEUROSURGICAL SOCIETY , THE JAPANESE CANCER ASSOCIATION

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