Rchr
J-GLOBAL ID：201801013144590166
Update date: Sep. 10, 2024
Keishi Kishimoto
Keishi Kishimoto
Affiliation and department：
Research field (1)：
Developmental biology
Research theme for competitive and other funds (5)：
- 2022 - 2025 呼吸器の組織構造をつくる基本原理としての自己組織化の解明
- 2019 - 2022 Elucidating the mechanism underlying the mesenchymal polarization of the trachea through Wnt signaling
- 2019 - 2022 気管及び食道オルガノイドの立体構造の作成基盤確立と間充織極性化機構の解明
- 2017 - 2019 The mechanism of mesenchymal cell polarity in mouse tracheal smooth muscle
- 2011 - 2012 多様な生命機能を司る新規遺伝子fad104に着目した創薬開発に向けての基盤研究
Papers (13)：
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Miao Y, Tan C, Pek NM, Yu Z, Iwasawa K, Kechele DO, Sundaram N, Pastrana-Gomez V, Kishimoto K, Yang MC, et al. Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids. bioRxiv. 2024
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Keishi Kishimoto, Kentaro Iwasawa, Alice Sorel, Carlos Ferran-Heredia, Lu Han, Mitsuru Morimoto, James M Wells, Takanori Takebe, Aaron M Zorn. Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems. Nature protocols. 2022. 17. 11. 2699-2719
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Alexandra K. Eicher, Daniel O. Kechele, Nambirajan Sundaram, H. Matthew Berns, Holly M. Poling, Lauren E. Haines, J. Guillermo Sanchez, Keishi Kishimoto, Mansa Krishnamurthy, Lu Han, et al. Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells. Cell Stem Cell. 2022. 29. 1. 36-51.e6
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Keishi Kishimoto, Mitsuru Morimoto. Mammalian tracheal development and reconstruction: insights from in vivo and in vitro studies. Development (Cambridge, England). 2021. 148. 13
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Lu Han, Praneet Chaturvedi, Keishi Kishimoto, Hiroyuki Koike, Talia Nasr, Kentaro Iwasawa, Kirsten Giesbrecht, Phillip C. Witcher, Alexandra Eicher, Lauren Haines, et al. Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis. Nature Communications. 2020. 11. 1
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MISC (5)：
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Keishi Kishimoto, Mitsuru Morimoto. Oriented mesenchymal cells drive tracheal tubulogenesis. MECHANISMS OF DEVELOPMENT. 2017. 145. S149-S149
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Hirofumi Kiyokawa, Keishi Kishimoto, Mitsuru Morimoto. Temporal Orchestration of Tissue Maturation with Proliferation Reduction and Cell Differentiation in Developing Trachea. MECHANISMS OF DEVELOPMENT. 2017. 145. S149-S149
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落合なつき, 城村由和, 岸本圭史, 長田茂宏, 西塚誠, 今川正良. 脂肪細胞分化を正に制御する新規遺伝子fad24の生体内における機能解析. 日本薬学会年会要旨集. 2011. 131st. 3. 103-103
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落合なつき, 城村由和, 岸本圭史, 長田茂宏, 西塚誠, 今川正良. 新規遺伝子fad24の生体内における機能解析. 生化学. 2010. 83回・33回. 4P-1061
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落合なつき, 城村由和, 岸本圭史, 渡邉佳代子, 長田茂宏, 西塚誠, 今川正良. 新規遺伝子fad24過剰発現マウスの解析とfad24ノックアウトマウスの樹立. 日本薬学会年会要旨集. 2010. 130th. 3. 71-71
Lectures and oral presentations (11)：
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Mechanism and reconstitution of trachea and esophageal patterning in mouse and human
(2024 RIKEN BDR-CuSTOM Joint Organoid Symposium 2024)
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発生学を応用したヒト臓器間充織細胞の誘導
(第64回呼吸器学会学術講演会 2024)
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気管の発生機構と幹細胞からの再構成
(Young Respiratory Scientists Spring Seminar 2024)
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Understanding and recapitulating trachea-esophageal development
(2023 RIKEN BDR-CuSTOM Joint Organoid Symposium 2023)
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Mechanism and in vitro reconstruction of mammalian trachea-esophageal development
(2023 CLEAR Consortium Symposium 2023)
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Education (3)：
- 2009 - 2012 Nagoya City University Graduate School of Pharmaceutical Sciences Department of Molecular Biology
- 2007 - 2009 Nagoya City University Graduate School of Pharmaceutical Sciences Department of Molecular Biology
- 2003 - 2007 Nagoya City University Medicin Medicin
Work history (2)：
- 2013/01 - 現在 理化学研究所生命機能科学研究センター 呼吸器形成研究チーム 研究員
- 2019/12 - 2024/12 シンシナティ小児病院
Awards (6)：
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