Rchr
J-GLOBAL ID:201801013224197104
Update date: Oct. 26, 2024
Minato Yusuke
ミナト ユウスケ | Minato Yusuke
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://www.fujita-hu.ac.jp/~microb/index.html
Research field (3):
Genomics
, Pharmaceuticals - health and biochemistry
, Bacteriology
Research keywords (10):
抗菌薬創薬
, 抗菌薬相互作用
, 病原細菌
, 細菌代謝
, 結核
, 非結核性抗酸菌(NTM)
, 機能ゲノム解析
, 薬剤耐性
, コレラ
, ペスト
Research theme for competitive and other funds (15):
- 2023 - 2029 バイオヒステリシスを考慮した難治性感染症の治療抵抗性要因の解明と普遍的効果を示す次世代型抗菌薬創薬への応用
- 2024 - 2028 sRNAs-CsrA統合制御システムの環境シグナルによる遺伝子発現調節機構の解明
- 2024 - 2027 結核菌や非結核性抗酸菌の赤血球接着型鉄成分獲得経路と増殖メカニズムの解明
- 2023 - 2026 非結核性抗酸菌が抗結核薬に耐性を示すメカニズムの解明と新規治療法開発への応用
- 2023 - 2026 Elucidation of factors affecting environmental persistence of non-tuberculous Mycobacterium tuberculosis and related genomic factors
- 2023 - 2026 非結核性抗酸菌が抗結核薬に耐性を示すメカニズムの解明と新規治療法開発への応用
- 2021 - 2024 機能性sRNAとmRNA結合タンパク質CsrAによる統合型発現制御システムの解明
- 2021 - 2024 Identification of novel dual-acting bactericidal drug targets against Mycobacterium tuberculosis
- 2021 - 2024 結核対策困難化要因に対する総合的基礎研究
- 2020 - 2023 Expanding functional genomics of nontuberculous mycobacteria for establishing strategies for prevention, predictive diagnosis and drug development
- 2020 - 2023 Elucidation of environmental adaptation mechanism of non-tuberculous mycobacteria by multi-genomic analysis and establishment of protective basis against their infection
- 2020 - 2023 難治性・多剤耐性結核に対する革新的治療法の開発とその提供体制に関する総合的研究
- 2021 - 2022 非結核性抗酸菌症治療薬創出のための標的検証
- 2020 - 2022 コエンザイム A 生合成経路を標的とした抗結核薬の開発
- 2020 - 2021 オミックス情報に基づく結核感染制御技術の開発研究
Show all
Papers (32):
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Kenta Morita, Tomoko Moriwaki, Shunsuke Habe, Mariko Taniguchi-Ikeda, Tadao Hasegawa, Yusuke Minato, Takashi Aoi, Tatsuo Maruyama. Molecular Aggregation Strategy for Inhibiting DNases. JACS Au. 2024. 4. 6. 2262-2266
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Takeshi Nakaya, Miyuki Yabe, Ellene H Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi, et al. Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY. Nature communications. 2022. 13. 1. 7575-7575
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Shintaro Kusaka, Kazuki Yamamoto, Motoko Shinohara, Yusuke Minato, Satoshi Ichikawa. Synthesis of capuramycin and its analogues via a Ferrier-type I reaction and their biological evaluation. Bioorganic & medicinal chemistry. 2022. 73. 117011-117011
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Malcolm S Cole, Michael D Howe, Joseph A Buonomo, Sachin Sharma, Elise A Lamont, Scott I Brody, Neeraj K Mishra, Yusuke Minato, Joshua M Thiede, Anthony D Baughn, et al. Cephem-Pyrazinoic Acid Conjugates: Circumventing Resistance in Mycobacterium tuberculosis. Chemistry (Weinheim an der Bergstrasse, Germany). 2022
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Shintaro Kusaka, Kazuki Yamamoto, Motoko Shinohara, Yusuke Minato, Satoshi Ichikawa. Design, synthesis and conformation-activity relationship analysis of LNA/BNA-type 5'-O-aminoribosyluridine as MraY inhibitors. Bioorganic & medicinal chemistry. 2022. 65. 116744-116744
more...
Education (3):
- 2003 - 2008 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
- 2003 - 2005 Okayama University The Graduate School of Natural Science and Technology
- 1999 - 2003 Okayama University Faculty of Pharmaceutical Sciences
Professional career (1):
Work history (5):
- 2024/04 - 現在 Fujita Health University
- 2019/10 - 2024/03 Fujita Health University School of Medicine Faculty of Medicine Senior Assistant Professor
- 2013/04 - 2019/09 University of Minnesota Medical School Research Associate
- 2009/09 - 2013/02 Oregon State University Postdoctoral Scholar
- 2008/06 - 2009/09 UCLA postdoctoral Fellow
Association Membership(s) (3):
american society for microbiology
, ゲノム微生物学会
, JAPANESE SOCIETY FOR BACTERIOLOGY
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