Research theme for competitive and other funds (6)：
2020 - 2023 The study of the mood system by single cellular analysis of bipolar model animal
2017 - 2022 Role of paraventricular thalamic nucleus in bipolar disorder
2020 - 2022 Single Cellular Pathophysiology of Bipolar Model
2018 - 2021 Significance of MAOB in paraventricular nucleus-specific mitochondrial defects that relevant to a cause of mood disorders
平面内細胞極性及び神経突起形成に関与する遺伝子のマウスにおける役割の解析
Study on the gene participating planar cell polarity and neurite formation in mouce
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Papers (20)：
Yasuyuki Shima, Henrik Skibbe, Yohei Sasagawa, Noriko Fujimori, Yoshimi Iwayama, Ayako Isomura-Matoba, Minoru Yano, Takumi Ichikawa, Itoshi Nikaido, Nobutaka Hattori, et al. Distinctiveness and continuity in transcriptome and connectivity in the anterior-posterior axis of the paraventricular nucleus of the thalamus. Cell Reports. 2023. 42. 10. 113309-113309
Yasuyuki Shima, Shota Sasagawa, Nakao Ota, Rieko Oyama, Minoru Tanaka, Mie Kubota-Sakashita, Hirochika Kawakami, Mika Kobayashi, Naoko Takubo, Atsuko Nakanishi Ozeki, et al. Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms. Science Translational Medicine. 2023. 15. 700
David Levitan, Chenghao Liu, Tracy Yang, Yasuyuki Shima, Jian-You Lin, Joseph Wachutka, Yasmin Marrero, Ramin Ali Marandi Ghoddousi, Eduardo da Veiga Beltrame, Troy A Richter, et al. Deletion of Stk11 and Fos in mouse BLA projection neurons alters intrinsic excitability and impairs formation of long-term aversive memory. eLife. 2020. 9
Ken Sugino, Erin Clark, Anton Schulmann, Yasuyuki Shima, Lihua Wang, David L Hunt, Bryan M Hooks, Dimitri Tränkner, Jayaram Chandrashekar, Serge Picard, et al. Mapping the transcriptional diversity of genetically and anatomically defined cell populations in the mouse brain. eLife. 2019. 8. e38619
Camille Mazo, Julien Grimaud, Yasuyuki Shima, Venkatesh N Murthy, C Geoffrey Lau. Distinct projection patterns of different classes of layer 2 principal neurons in the olfactory cortex. Scientific reports. 2017. 7. 1. 8282-8282
