ISHII HIROSHI

イシイヒロシ | ISHII HIROSHI

Homepage URL (1)： http://med03.w3.kanazawa-u.ac.jp/

Research field (4)： Immunology , Orthopedics , Neuroanatomy and physiology , Neurosurgery

Research keywords (7)： nero-regeneration , Neuro-immune interaciton , Immune privilege , Subarachnoid hemorrhage , Cerebral vasospasm , Spinal cord injury , Unfolded protein response

Research theme for competitive and other funds (11)：

2023 - 2026 Involvement of sympathetic nervous hyperactivity on early brain injury after subarachnoid hemorrhage
2020 - 2023 好中球のRAGEによるクモ膜下出血後脳血管攣縮機構
2018 - 2022 Joint international research for developing new drugs in the cerebral vascular diseases by targeting RAGE signaling
2018 - 2022 Development of novel treatments for subarachnoid hemorrhage
2017 - 2020 Novel molecular immune mechanism underlying cerebral vasospasm after subarachnoid hemorrhage.

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Papers (21)：

Tsuyoshi Hattori, Stanislav M Cherepanov, Ryo Sakaga, Jureepon Roboon, Dinh Thi Nguyen, Hiroshi Ishii, Mika Takarada-Iemata, Takumi Nishiuchi, Takayuki Kannon, Kazuyoshi Hosomichi, et al. Postnatal expression of CD38 in astrocytes regulates synapse formation and adult social memory. The EMBO journal. 2023. 42. 15. e111247
Anastasiia Melnikova, Hiroshi Ishii, Takashi Tamatani, Tsuyoshi Hattori, Mika Takarada-Iemata, Osamu Hori. Neuroprotective role of calreticulin after spinal cord injury in mice. Neuroscience Research. 2023
Munehiro Demura, Hiroshi Ishii, Mika Takarada-Iemata, Tomoya Kamide, Akifumi Yoshikawa, Mitsutoshi Nakada, Osamu Hori. Sympathetic Nervous Hyperactivity Impairs Microcirculation Leading to Early Brain Injury After Subarachnoid Hemorrhage. Stroke. 2023
Qiyan Fan, Mika Takarada-Iemata, Nahoko Okitani, Takashi Tamatani, Hiroshi Ishii, Tsuyoshi Hattori, Sumiko Kiryu-Seo, Hiroshi Kiyama, Osamu Hori. Brain injury triggers cell-type-specific and time-dependent endoplasmic reticulum stress responses. Glia. 2022
Jureepon Roboon, Tsuyoshi Hattori, Dinh Thi Nguyen, Hiroshi Ishii, Mika Takarada-Iemata, Takayuki Kannon, Kazuyoshi Hosomichi, Takashi Maejima, Kengo Saito, Yohei Shinmyo, et al. Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes. Frontiers in Cellular Neuroscience. 2022. 16

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MISC (2)：

Tanabe Shogo, Hiroshi Ishii, Toshihide Yamashita. RGMa expressed on Th17 induces neuronal cell death. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 107P-107P
Hiroshi Ishii, Takekazu Kubo, Toshihide Yamashita. Implantation of Th1 cells ameliorates recovery after spinal cord injury. NEUROSCIENCE RESEARCH. 2010. 68. E76-E76

Patents (3)：

COMPOSITION FOR TREATING CEREBRAL VASOSPASM AFTER SUBARACHNOID HEMORRHAGE;AND USE THEREOF
COMPOSITION FOR TREATING CENTRAL NERVE DAMAGE;AND USE THEREOF
COMPOSITION FOR TREATING CENTRAL NERVE DAMAGE;AND USE THEREOF

Education (2)：

2007 - 2011 Chiba University Graduate School of Medicine Ph.D. / Advanced Life Science
2001 - 2005 Osaka University M.D. / School of Medicine

Professional career (1)：

博士(医学) (千葉大学)

Work history (2)：

2015/08 - 現在 Kanazawa University Graduate School of Medicine
2013/09 - 2015/07 Columbia University Columbia Center for Translational Immunology Yasuda Memorial Medical Foundation Fellow, Uehara Memorial Life Science Foundation Fellow

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