Research theme for competitive and other funds (3)：
2021 - 2024 Molecular mechanisms of involvment of vanin-1 with kidney disease and its application to drug discovery
2000 - 2002 Search and development of antitumor sed compounds produced yb microorganisms from marine organisms
1998 - 1999 Development of antitumor lead compounds produced by microorganisms from marine organisms
Papers (44)：
Hiroki Yoneyama, Ayami Okada, Noboru Hayama, Shinya Harusawa, Yoshihide Usami. Transformation of Benzaldehydes to Benzonitriles via Cyanophosphates without One-carbon Homologation. Synthesis (Germany). 2024
Shizuyo Horiyama, Noboru Hayama, Hiroki Yoneyama, Yoshihide Usami, Jun Haginaka. Identification of novel metabolites of abiraterone in human serum and their metabolic pathways. Analytical Sciences. 2024. 40. 1. 67-74
Yoshihide Usami, Kimika Nakamura, Yoshino Mizobuchi, Koji Mizuki, Shinya Harusawa, Hiroki Yoneyama, Takeshi Yamada. Enantiomeric composition of natural pericosine A derived from Periconia byssoides and alpha-glycosidase inhibitory activity of (-)-enantiomer. CHIRALITY. 2022
Hiroki Yoneyama, Keiko Hosohata, Denan Jin, Iroha Yoshida, Miyui Toyoda, Ikuko Kitamura, Shinji Takai, Yoshihide Usami. Design, synthesis, and evaluation of new vanin-1 inhibitors based on RR6. Bioorganic and Medicinal Chemistry. 2022. 65
Yoshihide Usami, Yoshino Mizobuchi, Mai Ijuin, Takeshi Yamada, Mizuki Morita, Koji Mizuki, Hiroki Yoneyama, Shinya Harusawa. Synthesis of 6-Halo-Substituted Pericosine A and an Evaluation of Their Antitumor and Antiglycosidase Activities. Marine Drugs. 2022. 20. 7
宮本京香, 新子紗矢, 野村有佐, 植沢芳広, 葉山登, 米山弘樹, 宇佐美吉英. Efforts toward Synthesis of Pericosine E Analogs Bearing A Halogen Atom Other Than Chlorine. 日本薬学会年会要旨集(Web). 2023. 143rd
葉山登, 堀山志朱代, 西由紀菜, 矢田麻奈衣, 米山弘樹, 萩中淳, 宇佐美吉英. Identification of unknown metabolites of abiraterone. 日本薬学会年会要旨集(Web). 2023. 143rd
