Sakurai Kaori

Affiliation and department：
Job title： Associate Professor
Other affiliations (2)：

Tokyo University of Agriculture and Technology Faculty of Engineering, Department of Biotechnology and Life Science
Tokyo University of Agriculture and Technology Graduate School of Engineering, Department of Biotechnology and Life Science

Homepage URL (1)： http://web.tuat.ac.jp/~sakurai/

Research field (5)： Molecular biochemistry , Bioorganic chemistry , Chemical biology , Synthetic organic chemistry , Biochemistry

Research keywords (10)：ケミカルバイオロジー , 生物有機化学 , 天然物化学 , 生理活性物質 , 抗がん活性天然物 , サポニン , 化学プローブ , フォトアフィニティーラベリング , 標的タンパク質 , 金ナノ粒子

Research theme for competitive and other funds (10)：

2022 - 2027 Upgrading architecturally complex natural products: innovations in total synthesis and high-throughput generation of analogues and functional molecules
2021 - 2024 未知標的タンパク質探索のための新規基盤技術の確立
2018 - 2020 金ナノ粒子を用いた医薬品標的タンパク質の効率的探索法の開発
2018 - 2018 巨大複雑天然物群の網羅的創出による未踏創薬モレキュラースペースの開拓
2017 - 2017 生体モデル膜における脂質分子の動的配座とドメイン構造

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Papers (46)：

Myat Nyein Khine, Kaori Sakurai. Golgi-Targeting Anticancer Natural Products. CANCERS. 2023. 15. 7
Kentaro Oh-hashi, Hibiki Nakamura, Hirotaka Ogawa, Yoko Hirata, Kaori Sakurai. Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells. International Journal of Molecular Sciences. 2023. 24. 6
Sakurai Kaori. Chemical probe-based approach to discovery of target proteins of natural products. Journal of The Society of Japanese Women Scientists. 2023. 23. 22-30
Micha Fridman, Kaori Sakurai. Deciphering the Biological Activities of Antifungal Agents with Chemical Probes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2023
Shione Kamoshita, Saho Matsui, Nanako Suto, Kaori Sakurai. Reactivity Analysis of New Multivalent Electrophilic Probes for Affinity Labeling of Carbohydrate Binding Proteins. CHEMBIOCHEM. 2022. 23. 4

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Patents (1)：

化合物、該化合物を用いた金属ナノ粒子複合体、及び標的分子の検出方法

Books (1)：

ケミカルバイオロジー化合物周ー研究展開のヒントー
オーム社 2018 ISBN:9784274507090

Lectures and oral presentations (95)：

Target Identificaiton
(Asian Chemical Biology Initiative Jakarta Meeting 2019)
Development of gold nanoparticle-based affinity labeling probes for analyzing carbohydrate-binding proteins
(2nd Australasian Glycoscience Symposium-18th World HUPO Congress 2019)
Development of gold nanoparticle-based clickable photoaffinity probes for target protein identification
(2nd Australasian Glycoscience Symposium-18th World HUPO Congress 2019)
Development of gold nanoparticle-based multivalent photoaffinity probes toward exploration of carbohydrate-protein interaction
(2nd Australasian Glycoscience Symposium-18th World HUPO Congress 2019)
糖鎖結合タンパク質探索のための金ナノ粒子プローブ開発
(H30年度 TIAナノバイオスクール(糖鎖・レクチン) 2019)

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Awards (4)：

2022 - 一般社団法人日本女性科学者の会第27回(2022年度)日本女性科学者の会奨励賞天然生物活性分子の標的タンパク質探索技術の開発と作用機構解明研究
2019 - Southern University of Science and Technology The 146th SUSTECH Chemical Sciences Lectureship Award
2009 - International Human Frontier Science Program Organization Human Frontier Science Program Young Investigator Grant Award
2005/08 - 天然物化学談話会第五回天然物化学談話会奨励賞受賞

Association Membership(s) (9)：

Japanese Chemical Biology Society , American Chemical Society , 日本化学会 , 日本糖質学会 , 日本薬学会 , 有機合成化学協会 , The Human Proteome Organization , 東京糖鎖研究会 , 新規素材探索研究会

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