Kawahara Yukio

カワハラユキオ | Kawahara Yukio

Affiliation and department：
Job title：教授
Homepage URL (1)： http://www.med.osaka-u.ac.jp/pub/rna/p_kawahara.html

Research field (2)： Molecular biology , Pathobiochemistry

Research keywords (5)： RNA editing/modifications , Z-RNA , RNA biology , amyotrophic lateral sclerosis (ALS) , neurodegenerative diseases

Research theme for competitive and other funds (19)：

2023 - 2026 RNA編集不全に起因する自己免疫性脳症発症メカニムズの解明
2022 - 2025 修飾塩基を含むRNAの二次構造解析技術の確立
2020 - 2023 RNA編集酵素ADAR1の脳特異的機能の解明
2019 - 2022 RNA secondary structure prediction using nanopore sequencers
2019 - 2021 Establishment of the mothod for RNA labelling in a neuron subtype-specific manner in vivo

Show all

Papers (52)：

Kotaro Miyake, Pedro Henrique Costa Cruz, Izumi Nagatomo, Yuki Kato, Daisuke Motooka, Shingo Satoh, Yuichi Adachi, Yoshito Takeda, Yukio Kawahara, Atsushi Kumanogoh. A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth. Cell Reports. 2023. 42. 7. 112688-112688
Yanfang Xing, Taisuke Nakahama, Yuke Wu, Maal Inoue, Jung In Kim, Hiroyuki Todo, Toshiharu Shibuya, Yuki Kato, Yukio Kawahara. RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing. Journal of Biological Chemistry. 2023. 299. 7. 104840-104840
Taisuke Nakahama, Yukio Kawahara. The RNA-editing enzyme ADAR1: a regulatory hub that tunes multiple dsRNA-sensing pathways. International Immunology. 2022. 35. 3. 123-133
Masanori Yoshinaga, Kyuho Han, David W. Morgens, Takuro Horii, Ryosuke Kobayashi, Tatsuaki Tsuruyama, Fabian Hia, Shota Yasukura, Asako Kajiya, Ting Cai, et al. The N6-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity. Nature Communications. 2022. 13. 1. 6435-6435
Reiichi Sugihara, Yuki Kato, Tomoya Mori, Yukio Kawahara. Alignment of single-cell trajectory trees with CAPITAL. Nature Communications. 2022. 13. 1. 5972

ｍore...

MISC (49)：

N/A. Clinical Neuroscience. 2023. 41. 5. 684-686
Taisuke Nakahama, Yukio Kawahara. Type I interferonopathies caused by dysregulation of RNA metabolism. 2022. 40. 15. 2505-2512
Yukio Kawahara. RNA editing: its physiological functions and application to gene modification technology. 2022. 40. 12. 1952-1958
Yukio Kawahara. Left-handed RNA as a novel molecular pattern recognized by innate immune system. Clinical Immunology & Allergology. 2022. 78. 1. 111-117
Taisuke Nakahama, Yukio Kawahara. Reduced RNA editing activity of ADAR1 p150 induces Aicardi-Goutières syndrome-like symptoms in mice. Clinical Immunology & Allergology. 2022. 77. 6. 737-743

ｍore...

Books (1)：

Post-transcriptional gene regulation by an Editor: ADAR and its role in RNA Editing.
Wiley-VCH book 2013 ISBN:9783527322022

Education (2)：

2000 - 2004 Graduate School of Medicine, The University of Tokyo PhD student
1989 - 1995 The University of Tokyo Department of Medicine

Professional career (1)：

博士(医学) (東京大学)

Work history (6)：

2014/04 - 現在 Graduate School of Medicine, Osaka University Department of RNA Biology and Neuroscience Professor
2013/04 - 2014/03 Graduate School of Medicine, Osaka University Laboratory of RNA function Associate Professor
2008/12 - 2013/03 Graduate School of Medicine, Osaka University Laboratory of RNA function Associate Proessor (tenura-track)
2004/06 - 2008/11 The Wistar Institute Nishikura's laboratory Postdoctoral fellow
2004/04 - 2004/05 The University of Tokyo Hospital Department of Neurology JSPS postdoctoral fellow

Show all

Association Membership(s) (8)：

The RNA Society , The American Association of Immunologists , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , THE JAPANESE SOCIETY FOR IMMUNOLOGY , THE RNA SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPAN NEUROSCIENCE SOCIETY , JAPANESE SOCIETY OF NEUROLOGY

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page