Seno Akimasa

Affiliation and department：
Job title： Research assistant professor
Homepage URL (1)： http://www.cyber.biotech.okayama-u.ac.jp/senolab/

Research field (1)： Tumor biology

Research theme for competitive and other funds (1)：

2018 - 2021 Induction of cancer stem cell-like cells by endothelin 1 and prediction of cancer treatment using its receptor inhibitor

Papers (59)：

Said M Afify, Ghmkin Hassan, Maram H Zahra, Hend M Nawara, Hagar A Abu Quora, Amira Osman, Hager Mansour, Kazuki Kumon, Akimasa Seno, Ling Chen, et al. Cancer stem cells as the source of tumor associated myoepithelial cells in the tumor microenvironment developing ductal carcinoma in situ. Biomaterials. 2023. 301. 122249-122249
Ghmkin Hassan, Said M Afify, Maram H Zahra, Hend M Nawara, Kazuki Kumon, Yoshiaki Iwasaki, David S Salomon, Akimasa Seno, Masaharu Seno. GSK-3α/β and MEK inhibitors assist the microenvironment of tumor initiation. Cytotechnology. 2023. 75. 3. 243-253
Hideki Minematsu, Said M Afify, Yuki Sugihara, Ghmkin Hassan, Maram H Zahra, Akimasa Seno, Masaki Adachi, Masaharu Seno. Cancer stem cells induced by chronic stimulation with prostaglandin E2 exhibited constitutively activated PI3K axis. Scientific reports. 2022. 12. 1. 15628-15628
Hager Mansour, Said M. Afify, Ghmkin Hassan, Hagar A. Abu Quora, Hend M. Nawara, Maram H. Zahra, Juan Du, Sadia Monzur, Toshiaki Ohara, Akimasa Seno, et al. A comparative study of metastatic potentials of three different cancer stem cell models. Advances in Cancer Biology - Metastasis. 2022. 100062-100062
Said M Afify, Ghmkin Hassan, Hend M Nawara, Maram H Zahra, Yanning Xu, Md Jahangir Alam, Koichi Saitoh, Hager Mansour, Hagar A Abu Quora, Mona Sheta, et al. Optimization of production and characterization of a recombinant soluble human Cripto-1 protein inhibiting self-renewal of cancer stem cells. Journal of cellular biochemistry. 2022

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MISC (9)：

峯松秀希, 峯松秀希, 杉原有貴, 大谷敬亨, 杜娟, MARAM Zahara Zaky, 妹尾彬正, 岡田宣宏, 妹尾昌治. マウス人工多能性幹細胞のがん幹細胞化におけるプロスタグランジンE2の関与. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
三村祐稀, CAHYA Apriliana, MARAM Zahra Zaky, 妹尾彬正, 岡田宣宏, 妹尾昌治. ヒトグリオブラストーマ由来細胞株U251MG細胞からのがん幹細胞の単離. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
上野舜介, 杜娟, 佐々田沙紀, HUSSEIN ZAKY ZAHRA Maram, 岡田宣宏, 妹尾彬正, 妹尾昌治. 増強されたCCR6/CCL20/IL17軸の発現はmiPS細胞の癌幹細胞への変換に関与する。. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd
小瀬みはる, 妹尾彬正, ZAHRA Maram Hussein Zaky, 岡田宣弘, 岩崎良章, 妹尾昌治. ヒトiPS細胞を用いた膵臓がん幹細胞モデルの作成. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st
妹尾昌治, OO Aung Ko Ko, 妹尾彬正, ZAHRA Maram Hussein Zaky, 岡田宣宏, 岩崎良章. がん幹細胞モデルにおけるCpGアイランドの低メチル化とPI3K-Aktシグナルの活性化. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st

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Education (3)：

2011 - 2014 The University of Tokyo Graduate School of Frontier Sciences Department of Computational Biology
2009 - 2011 The University of Tokyo Graduate School of Frontier Sciences Department of Computational Biology
2005 - 2009 Tokyo University of Science Faculty of Pharmaceutical Sciences Department of Pharmacy

Professional career (1)：

博士(科学) (東京大学大学院)

Work history (8)：

2022/04 - 現在片山化学工業株式会社ライフサイエンス事業推進室
2021/05 - 2022/03 the Laboratory of Natural Food and Medicine, co. Ltd. President
2021/04 - 2022/03 Okayama University Interdisciplinary Science and Engineering in Health Systems Research Assistant Professor
2018/04 - 2021/03 Okayama University Graduate School of Interdisciplinary Science and Engineering in Health Systems Research Assistant Professor
2019/12 - 2020/10 Wayne state University Eugene Applebaum College of Pharmacy and Health Sciences Visiting professor

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Association Membership(s) (5)：

American Association for Cancer Research , American Society for Cell Biology , The Molecular Biology Society of Japan , Japanese Cancer Assosication , Japanese Society for Immunology

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