Nobuhiko Tanaka

Affiliation and department：

Research field (5)： Systems genomics , Genetics , Laboratory animal science , Statistical science , Biological, health, and medical informatics

Research keywords (6)： machine learning , phenome , big data , mouse , data mining , phenotype

Research theme for competitive and other funds (4)：

2021 - 2024 マウスの個体異常を高精度に検出可能なワークフローの開発
2020 - 2022 Roles of Y chromosome genes on the sex spectrum of body balance
2020 - 2021 マウスの個体レベルでの網羅的な臨床表現形質を用いて個体異常を高精度に検出可能なモデルを構築する
2016 - 2019 Development of a method to detect phenotypic abnormalities with high accuracy

Papers (30)：

Manuela A Oestereicher, Janine M Wotton, Shinya Ayabe, Ghina Bou About, Tsz Kwan Cheng, Jae-Hoon Choi, Dave Clary, Emily M Dew, Lahcen Elfertak, Alain Guimond, et al. Comprehensive ECG reference intervals in C57BL/6N substrains provide a generalizable guide for cardiac electrophysiology studies in mice. Mammalian genome : official journal of the International Mammalian Genome Society. 2023
Hiroshi Masuya, Daiki Usuda, Hatsumi Nakata, Naomi Yuhara, Keiko Kurihara, Yuri Namiki, Shigeru Iwase, Toyoyuki Takada, Nobuhiko Tanaka, Kenta Suzuki, et al. Establishment and application of information resource of mutant mice in RIKEN BioResource Research Center. Laboratory animal research. 2021. 37. 1. 6-6
Nobuhiko Tanaka, Hiroshi Masuya. An atlas of evidence-based phenotypic associations across the mouse phenome. Scientific reports. 2020. 10. 1. 3957
Hamed Haselimashhadi, Jeremy C Mason, Violeta Munoz-Fuentes, Federico López-Gómez, Kolawole Babalola, Elif F Acar, Vivek Kumar, Jacqui White, Ann M Flenniken, Ruairidh King, et al. Soft windowing application to improve analysis of high-throughput phenotyping data. Bioinformatics (Oxford, England). 2020. 36. 5. 1492-1500
Tao Zhang, Pancheng Xie, Yingying Dong, Zhiwei Liu, Fei Zhou, Dejing Pan, Zhengyun Huang, Qiaocheng Zhai, Yue Gu, Qingyu Wu, et al. High-throughput discovery of genetic determinants of circadian misalignment. PLoS genetics. 2020. 16. 1. e1008577

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MISC (44)：

Marie-Christine Birling, Atsushi Yoshiki, David J. Adams, Shinya Ayabe, Arthur L. Beaudet, Joanna Bottomley, Allan Bradley, Steve D. M. Brown, Antje Bürger, Wendy Bushell, et al. A resource of targeted mutant mouse lines for 5,061 genes. Nature Genetics. 2021. 53. 4. 416-419
櫛田達矢, 岩瀬秀, 湯原直美, 栗原恵子, 並木由理, 臼田大輝, 高田豊行, 田中信彦, 鈴木健大, 桝屋啓志. 理研バイオリソース研究センター(BRC)ホームページのリニューアル. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
桝屋啓志, 岩瀬秀, 田中信彦, 鈴木健大, 湯原直美, 臼田大輝, 栗原恵子, 並木由理, 佐藤道比古, 小幡裕一. 理研バイオリソース研究センターにおける情報整備. 日本実験動物学会総会講演要旨集(Web). 2019. 66th
田中信彦, 桝屋啓志. マウス表現型間の関係性の全景. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-1326]
高月照江, 高山英紀, 佐藤道比古, 谷川紀子, 高田豊行, 庫本高志, 成瀬清, 若菜茂晴, 田中信彦, 桝屋啓志. モデル生物表現型データポータルサイトJ-phenomeにおける情報統合の現状. 日本実験動物学会総会講演要旨集. 2017. 64th

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Books (2)：

Lectures and oral presentations (24)：

Inferring phenotypic expression trajectories using mouse clinical phenotypic data
(2021)
マウスの網羅的な臨床表現形質を用いた個体異常を高精度に検出可能なワークフローの開発
(第42回日本分子生物学会年会 2020年12月 2020)
A web portal of evidence-based phenotypic associations across mouse phenome
(2019)
マウスの表現型間の関係性の全体像
(第41回日本分子生物学会年会 2018)
マウス表現型間の関係性の全景
(第40回日本分子生物学会年会 2017)

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Education (1)：

1998 - 2001 Tokyo University of Agriculture and Technology United Graduate School of Agricultural Science Department of Science of Plant and Animal Production

Professional career (1)：

Work history (5)：

Awards (1)：

Association Membership(s) (2)：

JAPANESE ASSOCIATION FOR LABORATORY ANIMAL SCIENCE , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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