Nishiyama Masaaki

ニシヤママサアキ | Nishiyama Masaaki

Affiliation and department：
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Homepage URL (1)： http://ana1.w3.kanazawa-u.ac.jp/

Research field (5)： Molecular biology , Cell biology , Neuroscience - general , Psychiatry , Tumor biology

Research keywords (7)：エピジェネティクス , クロマチンリモデリング , 発達障害 , 自閉症 , 不妊症 , がん , 老化

Research theme for competitive and other funds (22)：

2019 - 2023 クロマチンリモデリングによる神経発生制御と自閉症の発症メカニズムの解明

2020 - 2022 Elucidation of the combined mechanism of autism and hearing loss and its application to treatment

2020 - 2022 ヒト型モデルマウスを用いた自閉症の神経回路の同定と治療への応用

2018 - 2021 Elucidation of the onset mechanism in human autism model mice and application to drug discovery development

2018 - 2020 Can autism be cured in adulthood?

2017 - 2019 ヒト型自閉症モデルマウスによる個性の形成メカニズムの解明

2016 - 2018 新規自閉症モデルマウスにおけるグリア機能制御の解明と治療への応用

2015 - 2018 Epigenetic regulation of stem cell aging and organismal aging

2015 - 2017 クロマチンリモデリングによる幹細胞老化と癌の制御機構の解明

2013 - 2016 ユビキチン化による鉄代謝制御システムの解明

2012 - 2015 Elucidation of the mechanisms that control aging and cancer by chromatin remodeling

2010 - 2015 Elucidation of mechanism underlying cell cycle regulation and development of therapeutic strategy

2010 - 2011 Research on epigenetic regulation of aging and cancer by CHD8/histone H1 complex

2008 - 2009 Duplin/CHD8によるp53の機能抑制と発がんに関する研究

2007 - 2008 ユビキチン化関連酵素E4Bによる神経変性防御機構の解明

2007 - 2008 )Elucidation of the regulatory mechanism of apoptosis by the chromatin remodeling factor CHD8

2006 - 2007 p53シグナルを抑制する新規がん遺伝子Duplinの発見と機能解析

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Papers (29)：

Taichi Shiraishi, Yuta Katayama, Masaaki Nishiyama, Hirotaka Shoji, Tsuyoshi Miyakawa, Taisuke Mizoo, Akinobu Matsumoto, Atsushi Hijikata, Tsuyoshi Shirai, Kouta Mayanagi, et al. The complex etiology of autism spectrum disorder due to missense mutations of CHD8. Molecular Psychiatry. 2024
Kenta Nitahara, Atsuki Kawamura, Yuka Kitamura, Kiyoko Kato, Satoshi H Namekawa, Masaaki Nishiyama. Chromatin remodeler CHD8 is required for spermatogonial proliferation and early meiotic progression. Nucleic acids research. 2024
Yudai Tanaka, Takuto Nakata, Hiroshi Hibino, Masaaki Nishiyama, Daisuke Ino. Classification of multiple emotional states from facial expressions in head-fixed mice using a deep learning-based image analysis. PLOS ONE. 2023. 18. 7. e0288930-e0288930
Atsuki Kawamura, Masaaki Nishiyama. Deletion of the autism-related gene Chd8 alters activity-dependent transcriptional responses in mouse postmitotic neurons. Communications biology. 2023. 6. 1. 593-593
Daisuke Ino, Yudai Tanaka, Hiroshi Hibino, Masaaki Nishiyama. A fluorescent sensor for real-time measurement of extracellular oxytocin dynamics in the brain. Nature methods. 2022

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Books (6)：

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Education (2)：

Professional career (1)：

Work history (7)：

2024/01 - 現在金沢大学新学術創成研究機構, 次世代医療創成研究コア, 社会脳発達研究ユニット, 教授
2017/10 - 現在 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
2017/06 - 2017/09 Kyushu University Medical Institute of Bioregulation
2009/05 - 2017/05 Kyushu University Medical Institute of Bioregulation
2008/04 - 2009/04 Kyushu University Medical Institute of Bioregulation

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Awards (11)：

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Association Membership(s) (3)：

THE JAPANESE ASSOCIATION OF ANATOMISTS , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPAN SOCIETY OF HEPATOLOGY

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