Research field (5):
Environmental and pharmaceutical development resources
, Applied biochemistry
, Applied molecular and cellular biology
, Home economics, lifestyle science
, Nutrition and health science
Research theme for competitive and other funds (7):
2022 - 2025 ウラルカンゾウの形質転換培養細胞によるグリチルリチン酸生成の代謝制御の解明
2019 - 2024 Genomic origin of chemodiversity in medicinal plants
2019 - 2023 国内産の重要薬用資源植物の統合ゲノム科学
2019 - 2022 Research on the production of terpenoid compounds by transformed cultured cells in Glycyrrhiza plant
2016 - 2019 Study for glycyrrhizin production in Glycyrrhiza plant.
2008 - 2010 Molecular biological control for high triterpenoid production in Glycyrrhiza plant.
2005 - 2007 大麻(アサ)の医薬化合物高生産を目的とした分子育種
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Papers (62):
Naoki Chiyo, Hikaru Seki, Takuya Kanamoto, Hiroshi Ueda, Mareshige Kojoma, Toshiya Muranaka. Glycyrrhizin Production in Licorice Hairy Roots Based on Metabolic Redirection of Triterpenoid Biosynthetic Pathway by Genome Editing. Plant & cell physiology. 2023
Manami Sakanishi, Soo Yeon Chung, Kentaro Fujiwara, Mareshige Kojoma, Toshiya Muranaka, Hikaru Seki. Disruption of a licorice cellulose synthase-derived glycosyltransferase gene demonstrates its in planta role in soyasaponin biosynthesis. Plant Cell Reports. 2023. 43. 1
Kojoma, M. Cultivation study of Lithospermum erythrorhizon to obtain “Shikon” as a purple dye and traditional medicine - root growth and shikonin derivatives content. Acta Hortic. 2023. 1361. 13-20
Kanji Niwa, Naonobu Tanaka, Yusei Shimomoto, Daisuke Tsuji, Sang-Yong Kim, Mareshige Kojoma, Kohji Itoh, Chin-Ho Chen, Kuo-Hsiung Lee, Yoshiki Kashiwada. Hyperdioxanes, dibenzo-1,4-dioxane derivatives from the roots of Hypericum ascyron. Journal of natural medicines. 2021. 75. 4. 907-914
MASARU TERASAKI, YUSAKU NISHIZAKA, WATARU MURASE, ATSUHITO KUBOTA, HIROYUKI KOJIMA, MARESHIGE KOJOMA, TAKUJI TANAKA, HAYATO MAEDA, KAZUO MIYASHITA, MICHIHIRO MUTOH, et al. Effect of Fucoxanthinol on Pancreatic Ductal Adenocarcinoma Cells from an N-Nitrosobis(2-oxopropyl)amine-initiated Syrian Golden Hamster Pancreatic Carcinogenesis Model. Cancer Genomics - Proteomics. 2021. 18. 3 Suppl. 407-423