Rchr
J-GLOBAL ID：201801014577301475   Update date: May. 08, 2024

Akiyama Tomohiko

アキヤマ トモヒコ | Akiyama Tomohiko
Affiliation and department：
Yokohama City University

About Yokohama City University


Research field  (3)： Developmental biology ,  Molecular biology ,  Genomics
Research keywords  (9)： ヒトゲノム ,  幹細胞 ,  転写因子 ,  エピジェネティクス ,  性差形成 ,  分化制御 ,  エンハンサー変異 ,  着床前初期胚 ,  反復配列
Research theme for competitive and other funds  (20)：
  • 2022 - 2025 ES細胞の分化過程において切り替わる転写調節機構の解明
  • 2022 - 2024 多能性を規定するエンハンサーループの維持と再構築機構の解明
  • 2020 - 2022 転写装置の性差形成機構の解明
  • 2020 - 2022 幹細胞のエンハンサー機能を支えるクロマチン継承機構
  • 2019 - 2022 The roles of histone demethylases in transcriptional process involved in cell differentiation
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Papers (35)：
  • Kazuki Furugori, Hidefumi Suzuki, Ryota Abe, Keiko Horiuchi, Tomohiko Akiyama, Tomonori Hirose, Atsushi Toyoda, Hidehisa Takahashi. Chimera RNA transcribed from integrated HPV18 genome with adjacent host genomic region promotes oncogenic gene expression through condensate formation. Genes to cells : devoted to molecular & cellular mechanisms. 2024
  • Tomohiko Akiyama, Kei-ichiro Ishiguro, Nana Chikazawa, Shigeru B H Ko, Masashi Yukawa, Minoru S H Ko. ZSCAN4-binding motif - TGCACAC is conserved and enriched in CA/TG microsatellites in both mouse and human genomes. DNA Research. 2023
  • Sonny Arora, Jianyu Yang, Tomohiko Akiyama, Daniela Q James, Alexis Morrissey, Thomas R Blanda, Nitika Badjatia, William K M Lai, Minoru S H Ko, B Franklin Pugh, et al. Joint sequence & chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin. bioRxiv : the preprint server for biology. 2023
  • Chie Kobori, Ryo Takagi, Ryo Yokomizo, Sakie Yoshihara, Mai Mori, Hiroto Takahashi, Palaksha Kanive Javaregowda, Tomohiko Akiyama, Minoru S H Ko, Kazuo Kishi, et al. Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3. Stem cell research & therapy. 2023. 14. 1. 242-242
  • Hidefumi Suzuki, Kazuki Furugori, Ryota Abe, Shintaro Ogawa, Sayaka Ito, Tomohiko Akiyama, Keiko Horiuchi, Hidehisa Takahashi. MED26-containing Mediator may orchestrate multiple transcription processes through organization of nuclear bodies. BioEssays : news and reviews in molecular, cellular and developmental biology. 2023. e2200178
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MISC (31)：
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Lectures and oral presentations  (7)：
  • Transcriptome Manipulation to Facilitate the Differentiation of Human Pluripotent Stem Cells
    (幹細胞シンポジウム(招待講演) 2018)
  • 転写因子導入によるヒト多能性幹細胞の分化誘導の自在化を目指して
    (熊本大学発生研セミナー(招待講演) 2017)
  • 転写因子およびクロマチン制御因子による分化誘導の自在化を目指して
    (分子生物学会フォーラム(招待講演) 2017)
  • ヒトES細胞の直接分化誘導に関わるaccessible chromatin構造
    (次世代生命科学研究会(招待講演) 2017)
  • Accelerated differentiation of human pluripotent stem cells by ectopic expression of histone demethylase
    (日本発生生物学会(招待講演) 2017)
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Education (3)：
  • 2005 - 2008 The University of Tokyo Graduate School of Frontier Sciences
  • 2003 - 2005 The University of Tokyo Graduate School of Frontier Sciences
  • 1999 - 2003 Waseda University School of Science and Engineering
Professional career (1)：
  • 博士(生命科学) (東京大学)
Work history (7)：
  • 2022/04 - 現在 Yokohama City University School of Medicine
  • 2020/04 - 2022/03 Keio University School of Medicine The Sakaguchi Laboratory
  • 2018/07 - 2020/03 Keio University School of Medicine
  • 2013/10 - 2018/06 Keio University School of Medicine
  • 2011/10 - 2013/09 National Institute on Aging, National Institutes of Health, USA 日本学術振興会海外特別研究員
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Awards (1)：
  • 2008/03 - 東京大学 Excellent Doctoral Thesis Award
Association Membership(s) (3)：
日本エピジェネティクス研究会 ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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