Rchr
J-GLOBAL ID:201801014646286866   Update date: Nov. 10, 2024

Nakazaki Masahito

Nakazaki Masahito
Affiliation and department:
Other affiliations (1):
  • Yale University  School of Medicine 
Homepage URL  (1): https://web.sapmed.ac.jp/regeneration/staff.php
Research field  (3): Orthopedics ,  Neurosurgery ,  Neuroscience - general
Research theme for competitive and other funds  (23):
  • 2024 - 2027 脳梗塞に対する骨髄幹細胞治療による神経回路の再構築の革新的MRIによる統合的解析
  • 2024 - 2027 慢性期脳梗塞に対する骨髄幹細胞治療における至適リハビリ条件の探索
  • 2024 - 2027 脊髄損傷に対する骨髄間葉系幹細胞移植による、脳脊髄の可塑性亢進メカニズムの解析
  • 2024 - 2025 Therapeutic strategies for cerebral infarction and spinal cord injury by activating plasticity throughout the central nervous system
  • 2024 - 2025 骨髄間葉系幹細胞由来細胞外小胞による脊髄損傷治療の最適化
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Papers (38):
  • Ryosuke Hirota, Masanori Sasaki, Satoshi Iyama, Kota Kurihara, Ryunosuke Fukushi, Hisashi Obara, Tsutomu Oshigiri, Tomonori Morita, Masahito Nakazaki, Takahiro Namioka, et al. Intravenous Infusion of Autologous Mesenchymal Stem Cells Expanded in Auto Serum for Chronic Spinal Cord Injury Patients: A Case Series. Journal of Clinical Medicine. 2024
  • Tomohiro Yamaki, Shinichi Oka, Satoshi Iyama, Masanori Sasaki, Rie Onodera, Yuko Kataoka-Sasaki, Takahiro Namioka, Ai Namioka, Masahito Nakazaki, Mitsuhiro Takemura, et al. Intravenous infusion of auto-serum-expanded autologous mesenchymal stem cells into chronic severe brain injury patients. Interdisciplinary Neurosurgery. 2024. 36. 101927-101927
  • Masahito Nakazaki, Karen L Lankford, Hideaki Yamamoto, Yoshiyuki Mae, Jeffery D Kocsis. Human mesenchymal stem-derived extracellular vesicles improve body growth and motor function following severe spinal cord injury in rat. Clinical and translational medicine. 2023. 13. 6. e1284
  • Masahito Nakazaki, Shinichi Oka, Hirotoshi Magota, Ryo Kiyose, Rie Onodera, Ryo Ukai, Yuko Kataoka-Sasaki, Masanori Sasaki, Osamu Honmou. Pharmacological Difference Between Platelet Aggregations in Cardioembolic Stroke Patients with Direct Oral Anticoagulants: A Pilot Study. Journal of Stroke and Cerebrovascular Diseases. 2022. 31. 7. 106520-106520
  • Masahito Nakazaki, Tomonori Morita, Karen L Lankford, Philip W Askenase, Jeffery D Kocsis. Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF-β upregulation, microvascular stabilization and functional recovery in a rodent model of severe spinal cord injury. Journal of extracellular vesicles. 2021. 10. 11. e12137
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MISC (38):
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Patents (5):
  • 脳梗塞の治療用医薬
  • 寿命延長剤
  • ステント内再狭窄の予防のための医薬組成物
  • 筋萎縮性側索硬化症の治療用医薬組成物
  • シナプス形成剤
Lectures and oral presentations  (2):
  • Systemic administration of mesenchymal stem cells inhibits reperfusion injury following intravenous rt-PA therapy for transient middle cerebral artery occlusion in rats
  • 米国神経外傷学会 (Neurotrauma) Plenary session 招待講演
Work history (5):
  • 2024/04 - 現在 札幌医科大学 医学部附属再生医療学研究所 神経再生医療学部門
  • 2024/04 - 現在 Yale University School of Medicine
  • 2022/09 - 2024/04 Yale University Associate Research Scientist
  • 2018/09 - 2021/08 Yale University Postdoctoral Associate
  • 2013/04 - 2018/08 Sapporo Medical University
Awards (5):
  • 2024/10 - 日本細胞外小胞学会学術集会奨励賞
  • 2018/03 - 上原財団海外留学助成 リサーチフェローシップ
  • 2018/03 - 日本脳卒中学会 最優秀口演賞
  • 2013/03 - 日本脳卒中学会 優秀ポスター賞
  • 2009/05 - ヨーロッパ脳卒中学会 Young Investigator Award
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