Rchr
J-GLOBAL ID:201801014668905624
Update date: Jun. 25, 2024
Suda Masayoshi
スダ マサヨシ | Suda Masayoshi
Affiliation and department:
Job title:
Research fellow
Other affiliations (1):
Research field (3):
Molecular biology
, Cardiology
, Internal medicine - General
Research keywords (11):
Aging
, Atherosclerosis
, Diabetes
, Heart failure
, Angiogenesis
, 血管新生
, 糖尿病
, 高血圧
, 心不全
, 動脈硬化
, 老化
Research theme for competitive and other funds (14):
- 2024 - 2028 Understanding Cellular Senescence Biology in Aging through an Enhanced Targeting Strategy
- 2024 - 2026 Development of cell type specific senolytics
- 2021 - 2024 he therapeutic potential of senolysis for Alzheimer disease
- 2021 - 2023 Elucidation of molecular mechanism of cellular senescence and development of senolytic therapy
- 2020 - 2021 Senolytic vacciantaion for cardiovascular diseases
- 2018 - 2021 Effect of osteoporosis therapy with receptor activator for NFkappa B ligand inhibitor on coronary calcifications
- 2018 - 2021 The therapeutic potential of senolysis targeting SAGP for age related disorders
- 2019 - 2020 新規老化分子SAGPを標的とした抗老化治療
- 2015 - 2018 The effects of physiological coagulation inhibitors and inflammation / aging on anticoagulant therapies
- 2015 - 2018 Ex Vivo Expanded Erythroblast-Transplantation versus autologous bone marrow mononuclear cell implantation for patient with critical limb ischemia
- 2015 - 2018 Elucidation of aging mechanism by novel aging related molecules
- 2018 - 新規老化分子SAGPを標的とした抗老化治療
- 2014 - 2017 Effect of osteoporosis therapy with receptor activator for NFkappa B ligand inhibitor on coronary calcifications
- 2012 - 2015 Long -term outcome of Ex Vivo Expanded Erythroblast-Transplantation for patient with critical limb ischemia
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Papers (41):
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Goro Katsuumi, Ippei Shimizu, Masayoshi Suda, Yohko Yoshida, Takaaki Furihata, Yusuke Joki, Chieh-Lun Hsiao, Liang Jiaqi, Shinya Fujiki, Manabu Abe, et al. SGLT2 inhibition eliminates senescent cells and alleviates pathological aging. Nature aging. 2024
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Masayoshi Suda, Karl H Paul, Utkarsh Tripathi, Tohru Minamino, Tamara Tchkonia, James L Kirkland. Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction. Endocrine Reviews. 2024
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Masayoshi Suda, Goro Katsuumi, Tamar Tchkonia, James L Kirkland, Tohru Minamino. Potential Clinical Implications of Senotherapies for Cardiovascular Disease. Circulation journal. 2024. 88. 3. 277-284
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南野 徹, 須田 将吉. 老化細胞除去ワクチン・除去薬による加齢関連性疾患治療開発. 医科学応用研究財団研究報告. 2024. 41. 32-36
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Goro Katsuumi, Masayoshi Suda, Ippei Shimizu, Yohko Yoshida, Takaaki Furihata, Yusuke Joki, Chieh Lun L Hsiao, Tohru Minamino. Abstract 14285: Sodium Glucose Co-Transporter 2 Inhibition Eliminates Senescent Cells Through Downregulation of PD-L1 and Improves Pathological Aging. Circulation. 2023. 148. Suppl_1
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MISC (78):
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須田 将吉, 南野 徹. 【老化と疾患-エイジング研究の進歩-】総論 セノリティクス(老化細胞除去治療). 日本臨床. 2024. 82. 1. 108-115
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須田 将吉, 南野 徹. 老化細胞を標的とした抗老化治療開発と皮膚老化. Aesthetic Dermatology. 2023. 33. 1. 36-46
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須田 将吉, 南野 徹. 【セノリティクス】老化細胞除去ワクチンによる加齢性変化の改善. 細胞. 2023. 55. 2. 84-87
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蕭捷倫, 勝海悟郎, 須田将吉, 清水逸平, 吉田陽子, 降旗高明, 上木裕介, 古内亮, 蕭詠てい, 唐敬遠, et al. Vaccination for senescence-associated glycoprotein ameliorates Alzheimer’s pathology and cognitive behavior in mice. 日本抗加齢医学会総会プログラム・抄録集. 2023. 23rd
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須田将吉, 南野徹. Elimination of senescent cells by using the immune system-Improvement of cardiovascular aging by senolytic vaccine. 医学のあゆみ. 2023. 287. 5. 367-373
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Lectures and oral presentations (35):
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Endothelial cell specific senescent cell clearance alleviated vascular stiffness and metabolic dysfunction in obese mice
(8th International Cell Senescence Association (ICSA) Conference 2023)
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Endothelial cell specific senescent cell clearance alleviated vascular stiffness and metabolic dysfunction in obese mice
(2023)
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Lysosomal stress in cellular senescence and elimination of senescent cells targeting lysosomal molecule
(2023)
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The therapeutic potential of senolysis for vascular diseases
(The Japanese Circulation Society 2021)
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Elimination of senescent cells targeting Senescence associated glycoprotein (SAGP) improved the atherosclerosis and diabetes
(American Heart Association (AHA) 2020 2020)
more...
Education (4):
- 2009 - 2012 千葉大学大学院 医学薬学府 博士課程
- 2005 - 2009 Chiba University School of Medicine
- 2003 - 2005 東京大学大学院 薬学系研究科 修士課程
- 1999 - 2003 The University of Tokyo Faculty of Pharmaceutical Sciences
Professional career (2):
- 修士(薬学) (東京大学)
- 博士(医学) (千葉大学)
Work history (10):
- 2024/04 - 現在 Mayo Clinic College of Medicine and Science
- 2021/09 - 現在 Mayo Clinic Departments of Medicine and Physiology and Biomedical Engineering Research fellow
- 2021/06 - 現在 Juntendo University
- 2020/04 - 2021/08 新潟大学医歯学総合病院 循環器内科 専任助教
- 2013/04 - 2020/03 Niigata University Medical and Dental Hospital, Cardiovascular Medicine
- 2017/10 - 2017/10 佐渡総合病院 循環器内科 医長
- 2015/12 - 2016/01 新潟大学地域医療教育センター 魚沼基幹病院 循環器内科 医長
- 2012/04 - 2013/03 千葉大学医学部附属病院 循環器内科
- 2011/04 - 2012/03 日本心臓血圧研究振興会附属 榊原記念病院
- 2009/04 - 2011/03 千葉市立青葉病院
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Awards (4):
- 2020/09 - 日本循環器学会 関東甲信越支部 第257回日本循環器学会関東甲信越地方会 Basic・Translational Research Award 最優秀賞
- 2019/07 - Basic Cardiovascular sciences New Investigator Travel Award
- 2018/12 - 日本血管生物医学会 若手研究奨励賞 最優秀賞
- 2018/04 - 日本心血管内分泌代謝学会 若手研究奨励賞
Association Membership(s) (6):
日本心臓病学会
, 日本血管生物医学会
, 日本心血管内分泌学会
, 日本抗加齢医学会
, 日本循環器学会
, 日本内科学会
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