2019 - 2022 Development of a new anticancer drug using a protein that has high affinity and specifically binds to mutant Ras
2020 - 2021 Rasを標的とした細胞膜透過性タンパク質の開発
2016 - 2019 蛋白質異常凝集の初期段階の解明・制御
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Papers (31):
Sora Nozaki, Masanori Hijioka, Xiaopeng Wen, Natsumi Iwashita, Junya Namba, Yoshiaki Nomura, Aoi Nakanishi, Soichiro Kitazawa, Ryo Honda, Yuji O. Kamatari, et al. Galantamine suppresses α-synuclein aggregation by inducing autophagy via the activation of α7 nicotinic acetylcholine receptors. Journal of Pharmacological Sciences. 2024
Teiko Komori Nomura, Satoshi Endo, Takuma Kuwano, Kazuya Fukasawa, Shigeo Takashima, Tomoki Todo, Kyoji Furuta, Takuhei Yamamoto, Eiichi Hinoi, Hiroko Koyama, et al. ARL-17477 is a dual inhibitor of NOS1 and the autophagic-lysosomal system that prevents tumor growth in vitro and in vivo. Scientific reports. 2023. 13. 1. 10757-10757
Tatsushi Nakayama, Ryo Honda, Kazuo Kuwata, Shigeyuki Usui, Bunji Uno. Electrochemical and Mechanistic Study of Superoxide Scavenging by Pyrogallol in N,N-Dimethylformamide through Proton-Coupled Electron Transfer. Electrochem. 2022
Tatsushi Nakayama, Ryo Honda, Kazuo Kuwata, Shigeyuki Usui, Bunji Uno. Electrochemical and Mechanistic Study of Reactivities of α-, β-, γ-, and δ-Tocopherol toward Electrogenerated Superoxide in N,N-Dimethylformamide through Proton-Coupled Electron Transfer. Antioxidants. 2021. 11. 1. 9-9