Uchibe Kenta

ウチベケンタ | Uchibe Kenta

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Anatomy , Oral medicine

Research keywords (3)： Developmental biology , 分子細胞生物学 , Molecular and cell biology

Research theme for competitive and other funds (8)：

2022 - 2025 レチノイン酸による骨の形成・維持の制御メカニズムの解明と臨床応用への発展
2019 - 2022 Regulation of bone regeneration by exosomes and sugar chains derived from mechanical stress highly reactive mesenchymal stem cells
2019 - 2022 Elucidation of the complex promoting mechanism of bone formation and cognitive function using bio-multimodal analysis
2016 - 2020 Elucidation of novel interactions between melatonin and bone metabolism regulating hormones / cytokines
2016 - 2018 The role of retinoic acd signaling in endochondral ossification

Show all

Papers (2)：

Mariko Seyama, Kaya Yoshida, Kayo Yoshida, Natsumi Fujiwara, Kisho Ono, Takanori Eguchi, Hotaka Kawai, Jiajie Guo, Yao Weng, Yuan Haoze, et al. Outer membrane vesicles of Porphyromonas gingivalis attenuate insulin sensitivity by delivering gingipains to the liver. Biochimica et Biophysica Acta - Molecular Basis of Disease. 2020. 1866. 6
Yusuke Sumitani, Kenta Uchibe, Kaya Yoshida, Yao Weng, Jiajie Guo, Haoze Yuan, Mika Ikegame, Hiroshi Kamioka, Hirohiko Okamura. Inhibitory effect of retinoic acid receptor agonists on in vitro chondrogenic differentiation. Anatomical science international. 2020. 95. 2. 202-208

MISC (14)：

Kaya Yoshida, Jumpei Teramachi, Kenta Uchibe, Mika Ikegame, Lihong Qiu, Di Yang, Hirohiko Okamura. Reduction of protein phosphatase 2A Cα promotes in vivo bone formation and adipocyte differentiation. Molecular and cellular endocrinology. 2018. 470. 251-258
Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment. PLoS One. 2018
Kenta Uchibe, Jiyeon Son, Colleen Larmour, Maurizio Pacifici, Motomi Enomoto-Iwamoto, Masahiro Iwamoto. Genetic and pharmacological inhibition of retinoic acid receptor function promotes endochondral bone formation. JOURNAL OF ORTHOPAEDIC RESEARCH. 2017. 35. 5. 1096-1105
Salin A. Chakkalakal, Kenta Uchibe, Michael R. Convente, Deyu Zhang, Aris N. Economides, Frederick S. Kaplan, Maurizio Pacifici, Masahiro Iwamoto, Eileen M. Shore. Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1(R206H) Fibrodysplasia Ossificans Progressiva (FOP) Mutation. JOURNAL OF BONE AND MINERAL RESEARCH. 2016. 31. 9. 1666-1675
Sayantani Sinha, Kenta Uchibe, Yu Usami, Maurizio Pacifici, Masahiro Iwamoto. Effectiveness and mode of action of a combination therapy for heterotopic ossification with a retinoid agonist and an anti-inflammatory agent. BONE. 2016. 90. 59-68

ｍore...

Lectures and oral presentations (17)：

ヒストン脱メチル化酵素Jmjd3は転写調節因子Runx2とOsterixを介して骨芽細胞分化を制御する
(第123回日本解剖学会総会・全国学術集会 2018)
Drug-Based Growth Restriction of the Targeted Bone by Synthetic Retinoid Nanoparticles
(ORS 2018 ANNUAL MEETING 2018)
蛋白質脱リン酸化酵素PP2A による骨肉腫細胞の増殖・転移能の制御機構
(2017 Bioscience retreat in Tosa 2017)
RARγ シグナリングと軟骨内骨化に関する研究の紹介
(2017 Bioscience retreat in Tosa 2017)
レチノイン酸受容体の局在に関する研究
(2017 Bioscience retreat in Tosa 2017)

ｍore...

Work history (6)：

2019/11 - 現在 Hiroshima University Graduate School of Biomedical and Health Sciences Associate Professor
2015/05 - 2019/10 - 岡山大学医歯薬学総合研究科助教
2015/05 - 2019/10 - Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
2012/02 - 2015/04 The Children's Hospital of Philadelphia Orthopaedic Surgery Post-Doctoral Fellow
2010/04 - 2012/01 Okayama University Hospital Fixed Prosthodontics

Show all

Association Membership(s) (5)：

日本軟骨代謝学会 , 歯科基礎医学会 , 日本解剖学会 , 日本口腔インプラント学会 , 日本補綴歯科学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page