Ito Yasuhiko

イトウヤスヒコ | Ito Yasuhiko

Affiliation and department：

Research field (1)： Tumor biology

Research keywords (5)：抗体の新たな細胞傷害活性の作用メカニズムの解明 , 癌の生態についての基礎知見を治療へ応用すること , 癌の転移のメカニズム , 癌の発生のメカニズム , 腫瘍学

Papers (18)：

Yu Koyama, Hiroya Okazaki, Yang Shi, Yoshihiro Mezawa, Zixu Wang, Mizuki Sakimoto, Akane Ishizuka, Yasuhiko Ito, Takumi Koyama, Yataro Daigo, et al. Increased RUNX3 expression mediates tumor-promoting ability of human breast cancer-associated fibroblasts. Cancer Medicine. 2023
Moe Iwai, Miniwan Tulafu, Shinsaku Togo, Hideya Kawaji, Kotaro Kadoya, Yukiko Namba, Jin Jin, Junko Watanabe, Takahiro Okabe, Moulid Hidayat, et al. Cancer-associated fibroblast migration in non-small cell lung cancers is modulated by increased integrin α11 expression. Molecular oncology. 2021. 15. 5. 1507-1527
Kosuke Mizukoshi, Yu Okazawa, Hiroshi Haeno, Yu Koyama, Kaidiliayi Sulidan, Hiromitsu Komiyama, Harumi Saeki, Naomi Ohtsuji, Yasuhiko Ito, Yutaka Kojima, et al. Metastatic seeding of human colon cancer cell clusters expressing the hybrid epithelial/mesenchymal state. Int J Cancer. 2020. 146. 9. 2547-2562
折茂彰, 伊藤恭彦, 目澤義弘, 醍醐弥太郎, 樋野興夫, 竹田和由, 浜田道昭, 松村優子. 癌関連線維芽細胞による中間型上皮間葉移行を呈した高転移性の乳癌細胞クラスター形成(CAF-induced partial epithelial-mesenchymal transition mediates formation of metastatic human breast tumor cell clusters). 日本癌学会総会記事. 2019. 78回. E-1041
Yuko Matsumura, Yasuhiko Ito, Yoshihiro Mezawa, Kaidiliayi Sulidan, Yataro Daigo, Toru Hiraga, Kaoru Mogushi, Nadila Wali, Hiromu Suzuki, Takumi Itoh, et al. Stromal fibroblasts induce metastatic tumor cell clusters via epithelial-mesenchymal plasticity. Life science alliance. 2019. 2

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MISC (14)：

Yu Koyama, Yoshihiro Mezawa, Yasuhiko Ito, Takumi Koyama, Yataro Daigo, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Keisuke Sugahara, et al. RUNX3 expression plays tumor-suppressive roles by inhibiting the inflammatory trait in human breast CAFs. CANCER SCIENCE. 2021. 112. 749-749
小山侑, 目澤義弘, 伊藤恭彦, 小山拓洋, 醍醐弥太郎, 高野淳, 宮城洋平, 横瀬智之, 山下年成, 菅原圭亮, et al. 乳腺癌関連線維芽細胞においてRUNX3の発現は炎症性サイトカインの発現を抑制することで腫瘍抑制的に働く. 日本癌学会総会記事. 2020. 79回. PJ13-1
小山侑, 目澤義弘, 伊藤恭彦, 小山拓洋, 醍醐弥太郎, 高野淳, 宮城洋平, 横瀬智之, 山下年成, 菅原圭亮, et al. 乳腺癌関連線維芽細胞においてRUNX3の発現は炎症性サイトカインの発現を抑制することで腫瘍抑制的に働く. 日本癌学会総会記事. 2020. 79回. PJ13-1
小山侑, 吉田剛, 伊藤恭彦, 目澤義弘, 小山拓洋, 菅原圭亮, 片倉朗, 折茂彰. 乳腺癌関連線維芽細胞におけるRUNX3の発現はTGF-βとSDF-1のクロストークおよびWNT-β-cateninシグナルを媒介する(RUNX3 expression mediates cross-talk between TGF-βand SDF-1 signaling and WNT-β-catenin signaling in human breast CAFs). 日本癌学会総会記事. 2019. 78回. P-1104
小山拓洋, 目澤義弘, 小山侑, 伊藤恭彦, 菅原圭亮, 樋野興夫, 片倉朗, 折茂彰. 癌関連線維芽細胞においてFOXO1は活性化筋線維芽細胞性を仲介する(Forkhead box protein O1 mediates the activated myofibroblastic state in carcinoma-associated fibroblasts). 日本癌学会総会記事. 2019. 78回. P-2284

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Patents (1)：

スーパー抗原遺伝子

Books (8)：

レンチウイルスベクターの効率的な回収法
羊土社 2018
癌内線維芽細胞と癌悪性化
一般社団法人呼吸研究 2015
Fibrosis and tumor progression
2015
がん細胞の浸潤・転移を促進するがん微小環境:がん内線維芽細胞を例に
学研メディカル秀潤社 2014
the genus Yersinia
Kluwer Academic Publishers 2004

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Lectures and oral presentations (34)：

抗panHLA2モノクロ-ナル抗体4713によるATL治療について
(第82回日本癌学会学術総会 2023)
リンパ腫におけるケラチンのタイプ別含有量に関する新しい知見
(第82回日本癌学会学術総会 2023)
Therapeutic effects of newly established anti-CD10 mAb on lymphoma and lung cancer cell lines
(The 80th Annual Meeting of the Japanese Cancer Assosiation 2021)
CAR B-therapy (Created Antibodies Reinforced by B cell therapy)
(The 80th Annual Meeting of the Japanese Cancer Assosiation 2021)
RUNX3 expression plays tumor-suppressive roles by inhibiting the inflammatory traits in human CAFs
(The 79th Annual Meeting of the Japanese Cancer Assosiation 2020)

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Education (3)：

1984 - 1989 大阪大学大学院理学研究科生物化学専攻
1982 - 1984 Tokyo University of Agriculture and Technology
1977 - 1981 Tokyo University of Agriculture and Technology Faculty of Agriculture

Work history (12)：

2021/06 - 現在 Juntendo University Graduate School of Medicine Department of Immunological Diagnosis
2020/01 - 2021/05 Juntendo University Graduate School of Medicine Department of Immunological Diagnosis
2019/04 - 2019/12 Juntendo University Faculty of Medicine
2018/01 - 2019/03 Juntendo University Faculty of Medicine
2012/03 - 2017/12 Juntendo University Faculty of Medicine

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Association Membership(s) (1)：

THE JAPANESE CANCER ASSOCIATION

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