2023 - 2024 Reconsideration of the concept of intractable diseases in modern societies with developing science and technology
2019 - 2022 Stem cell-based study of FSHD pathology
2019 - 2020 Development of a therapy for FSHD targetting chromatin structure
2017 - 2019 患者由来iPS細胞を用いた顔面肩甲上腕型筋ジストロフィの病態解析
Papers (9):
Mitsuru Sasaki-Honda, Kyoko Akatsuka, Tsutomu Sawai. Is epigenome editing non-inheritable? Implications for ethics and the regulation of human applications. Stem cell reports. 2023. 18. 11. 2005-2009
Mitsuru SASAKI-HONDA. Implications From Experiences as a Skeletal Muscle Disease Patient With Physical Handicaps in the Experimental Biology Filed. TRENDS IN THE SCIENCES. 2022. 27. 10. 10_10-10_14
Mitsuru Sasaki-Honda, Tatsuya Jonouchi, Meni Arai, Junjie He, Kazusa Okita, Satoko Sakurai, Takuya Yamamoto, Hidetoshi Sakurai. Hit-and-run silencing of endogenous DUX4 by targeting DNA hypomethylation on D4Z4 repeats in facioscapulohumeral muscular dystrophy. 2022
Satomi Mitsuhashi, So Nakagawa, Mitsuru Sasaki-Honda, Hidetoshi Sakurai, Martin C Frith, Hiroaki Mitsuhashi. Nanopore direct RNA sequencing detects DUX4-activated repeats and isoforms in human muscle cells. Human molecular genetics. 2021. 30. 7. 552-563