Rchr
J-GLOBAL ID：201801015419409060   Update date: Jun. 14, 2024

Inaoka Daniel Ken

イナオカ ダニエルケン | Inaoka Daniel Ken
Affiliation and department：
Nagasaki University Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN)

About Nagasaki University Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN)


Job title： Associate Professor
Other affiliations (2)：
  • Nagasaki University  School of Tropical Medicine and Global Health    Associate Professor
  • The University of Tokyo  Department of Biomedical Chemistry, School of International Health, Graduate School of Medicine   Guest Researcher
Research field  (8)： Bacteriology ,  Infectious disease ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - chemistry and drug development ,  Molecular biology ,  Structural biochemistry ,  Tumor biology ,  Parasitology
Research theme for competitive and other funds  (20)：
  • 2023 - 2026 Investigation of the strategy used by intestinal parasites to high sulfide concentration environment
  • 2020 - 2024 in silicoとロボットによる創薬支援システムの開発とシャーガス病治療薬探索
  • 2020 - 2023 マラリア原虫のミトコンドリアリボソームにおける低コストな翻訳機構の解明
  • 2020 - 2022 トリパノソーマクルージを標的にした天然物ライブラリー用のスクリーニングの探索
  • 2019 - 2022 Imaging the ATP metabolism in Trypanosoma cruzi intracellular amastigotes
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Papers (86)：
  • Takaya Sakura, Ryuta Ishii, Eri Yoshida, Kiyoshi Kita, Teruhisa Kato, Daniel Ken Inaoka. Accelerating antimalarial drug discovery with a new high-throughput screen for fast-killing compounds. 2024
  • Ryuta Ishii, Takaya Sakura, Daniel Ken Inaoka, Fuyuki Tokumasu. Glycolytic enzymes form membrane-less condensates in the malaria parasitePlasmodium falciparumby sensing glucose levels. 2024
  • Junpei Fukumoto, Minako Yoshida, Suzumi M. Tokuoka, Eri Saki H. Hayakawa, Shinya Miyazaki, Takaya Sakura, Daniel Ken Inaoka, Kiyoshi Kita, Jiro Usukura, Hideo Shindou, et al. Pivotal roles ofPlasmodium falciparumlysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization. 2024
  • Ryunosuke Yoshino, Nobuaki Yasuo, Yohsuke Hagiwara, Takashi Ishida, Daniel Ken Inaoka, Yasushi Amano, Yukihiro Tateishi, Kazuki Ohno, Ichiji Namatame, Tatsuya Niimi, et al. Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography. ACS Omega. 2023
  • Yukiko Miyazaki, Martijn W. Vos, Fiona J. A. Geurten, Pierre Bigeard, Hans Kroeze, Shohei Yoshioka, Mitsuhiro Arisawa, Daniel Ken Inaoka, Valerie Soulard, Koen J. Dechering, et al. A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multi-stage drug assays. Communications Biology. 2023. 6. 1
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MISC (21)：
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Patents (3)：
Lectures and oral presentations  (255)：
  • 新しいハイスループットスクリーニング法による速効性抗マラリア活性化合物探索系の構築
    (第93回日本寄生虫学会大会 2024)
  • リゾリン脂質アシル転移酵素(PfLPLAT1)は赤内期熱帯熱マラリア原虫(P. falciparum)の細胞同期進行とサイトストーム細胞内移行に必要である
    (第93回日本寄生虫学会大会 2024)
  • マラリア原虫赤内期の解糖系酵素の動態解析
    (第93回日本寄生虫学会大会 2024)
  • In silico prediction of TLR9-binding guanine quadruplex sequences in Leishmania genome
    (2024)
  • トリパノソーマ科原虫におけるオートファジー関連因子ATG12の同定
    (第93回日本寄生虫学会大会 2024)
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Professional career (1)：
  • Ph.D. Pharmaceutical Sciences (The University of Tokyo, Graduate School of Pharmacy)
Work history (6)：
  • 2019/04 - 現在 Nagasaki University Department of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN) Associate Professor
  • 2016/04 - 現在 The University of Tokyo Department of Biomedical Chemistry, School of International Health, Graduate School of Medicine Guest Researcher
  • 2016/04 - 現在 Nagasaki University School of Tropical Medicine and Global Health Associate Professor
  • 2011/10 - 2016/03 The University of Tokyo Graduate School of Medicine, School of International Health, Department of Biomedical Chemistry Assistant Professor
  • 2007/10 - 2011/09 The University of Tokyo Graduate School of Medicine, School of International Helth, Department of Biomedical Chemistry Assistant Professor
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Awards (3)：
  • 2019/02 - 平成31年 2月 9th KEMRI Annual Scientific and Health (KASH) Conference, Best Presenter Award
  • 2008/04 - 日本寄生虫学会 第77回日本寄生虫学会 ベストプレゼンテーション賞受賞
  • 2006/07 - 分子寄生虫ワークショップ 平成18年 7月 第14回分子寄生虫ワークショップ ベストプレゼンテーション賞受賞
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