Yutaka Tanaka

タナカユタカ | Yutaka Tanaka

Affiliation and department：
Job title：助教
Homepage URL (1)： http://www.tohoku-mpu.ac.jp/pharmacy/about/lp_b02/

Research field (1)： Pharmaceuticals - health and biochemistry

Research keywords (6)： Aspergillus , 糸状菌 , Galactofuranose , Stress Response , Sugar Chain , Cell Wall

Research theme for competitive and other funds (5)：

2024 - 2027 Transport mechanism of fungal-type galactomannan to the cell surface in Aspergillus fumigatus
2022 - 2025 糸状菌の細胞表層動態を可視化する~新しい薬剤標的スクリーニング系の開発に向けて~
2020 - 2022 Development of an evaluation system to measure the dynamics of cell wall polysaccharides in filamentous fungi.
2019 - 2022 Elucidation and Overcoming Multidrug Resistance Mechanisms in the Pathogenic Fungus Candida
2017 - 2020 The mechanisms maintaining galactofuranose sugar chains structure in fungal cell wall and its significance in host infection

Papers (19)：

Chihiro Kadooka, Yutaka Tanaka, Rintaro Kishida, Daisuke Hira, Takuji Oka. Discovery of α-(1→6)-linked mannan structures resembling yeast N-glycan outer chains in Aspergillus fumigatus mycelium. mSphere. 2024. 9. 5. e0010024
Chihiro Kadooka, Yutaka Tanaka, Daisuke Hira, Takuji Oka. Identification of a putative α-galactoside β-(1 → 3)-galactosyltransferase involved in the biosynthesis of galactomannan side chain of glucuronoxylomannogalactan in Cryptococcus neoformans. Frontiers in microbiology. 2024. 15. 1390371-1390371
Masato Sasaki, Kazuo Yamamoto, Takeshi Ueda, Hayato Irokawa, Kouki Takeda, Ryoya Sekine, Fumie Itoh, Yutaka Tanaka, Shusuke Kuge, Nobuyuki Shibata. One-carbon metabolizing enzyme ALDH1L1 influences mitochondrial metabolism through 5-aminoimidazole-4-carboxamide ribonucleotide accumulation and serine depletion, contributing to tumor suppression. SCIENTIFIC REPORTS. 2023. 13. 1. 13486
Chihiro Kadooka, Yutaka Tanaka, Daisuke Hira, Jun-Ichi Maruyama, Masatoshi Goto, Takuji Oka. Identification of galactofuranose antigens such as galactomannoproteins and fungal-type galactomannan from the yellow koji fungus (Aspergillus oryzae). Frontiers in microbiology. 2023. 14. 1110996-1110996
Chihiro Kadooka, Daisuke Hira, Yutaka Tanaka, Ken Miyazawa, Masaaki Bise, Shogo Takatsuka, Takuji Oka. Identification of an α-(1→6)-Mannosyltransferase Contributing To Biosynthesis of the Fungal-Type Galactomannan α-Core-Mannan Structure in Aspergillus fumigatus. mSphere. 2022. e0048422

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MISC (62)：

田中大, 小宮玲泉, 朝霧育美, 山崎寛之, 八木瑛穂, 伊藤文恵, 佐々木雅人, 内田龍児. Aspergillus fumigatus flbC遺伝子変異株における異株間不均質性. 日本医真菌学会雑誌. 2022. 63. Supplement 1
柴田信之, 佐々木雅人, 伊藤文恵, 田中大, 知花博治, 山口正視. Reactivity of an innate immune system with carbohydrate transferase deletion mutant of Candida glabrata. 千葉大学真菌医学研究センター報告. 2021. 24
柴田信之, 佐々木雅人, 伊藤文恵, 田中大, 知花博治, 山口正視. Reactivity of an innate immune system with carbohydrate transferase deletion mutant of Candida glabrata. 千葉大学真菌医学研究センター報告. 2020. 23
伊藤文恵, 宍戸啓介, 松本淳志, 田中大, 佐々木雅人, 柴田信之. Cell wall polysaccharide of pathogenic dematiaceous fungus Exophiala jeanselmei contains long-chain oligosaccharides composed of β-1, 2-linked mannose, an important antigenic structure of Candida species. 日本薬学会年会要旨集(CD-ROM). 2020. 140th (Web)
伊藤文恵, 宍戸啓介, 田中大, 佐々木雅人, 柴田信之. 病原性黒色真菌Exophiala jeanselmei細胞壁多糖の抗原構造およびβ-1,2結合マンノースから成る長鎖オリゴ糖の抗原性の解析. 日本薬学会東北支部大会講演要旨集. 2020. 59th

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Education (2)：

2009 - 2011 東北薬科大学大学院薬学部薬学研究科博士課程前期
2005 - 2009 Tohoku Pharmaceutical University

Professional career (1)：

博士 (東北医科薬科大学)

Work history (2)：

2019/04 - 現在 Tohoku Pharmaceutical University Department of Infection and Host Defense Assistant professor
2011/04 - 2019/03 Tohoku Medical and Pharmaceutical University

Association Membership(s) (3)：

Fungal Molecular Biology Society of Japan , THE JAPANESE SOCIETY FOR MEDICAL MYCOLOGY , THE PHARMACEUTICAL SOCIETY OF JAPAN

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