Rchr
J-GLOBAL ID:201801015550309195   Update date: Feb. 01, 2024

Ishibashi Mariko

Ishibashi Mariko
Affiliation and department:
Job title: senior assistant professor
Research field  (4): Molecular biology ,  Tumor biology ,  Immunology ,  Hematology and oncology
Research keywords  (7): Hematopoietic malignancy ,  免疫関連分子 ,  Molecular Oncology ,  Molecular biology ,  immune checkpoint ,  Cancer ,  Tumor microenvironment
Research theme for competitive and other funds  (17):
  • 2022 - 2025 骨髄微小環境におけるSiglec-15を介した多発性骨髄腫の病態進展機序の解明
  • 2020 - 2025 Whole gamma imaging to break through the physical limitation of positron emission tomography
  • 2023 - 2024 多発性骨髄腫における抑制型樹状細胞の解明とその克服に向けて
  • 2023 - 2024 多発性骨髄腫における免疫抑制性腫瘍微小環境の改善に向けて
  • 2022 - 2023 低pH骨髄腫微小環境に起因した腫瘍関連マクロファージの誘導機序の解明
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Papers (25):
  • Mariko Ishibashi, Miwako Takahashi, Taiga Yamaya, Yoichi Imai. Current and Future PET Imaging for Multiple Myeloma. Life. 2023. 13. 8. 1701-1701
  • Ryosuke Kinoshita, Mariko Ishibashi, Hiroshi Handa, Makoto Sasaki, Yoichi Imai, Norina Tanaka, Shigeki Ito, Mika Sunakawa-Kii, Yuta Kaito, Toshio Asayama, et al. The levels of serum soluble CD86 are correlated with the expression of CD86 variant 3 gene and are prognostic indicators in patients with myeloma. Experimental hematology. 2023
  • Wataru Nakajima, Kai Miyazaki, Masahiro Sakaguchi, Yumi Asano, Mariko Ishibashi, Tomoko Kurita, Hiroki Yamaguchi, Hiroyuki Takei, Nobuyuki Tanaka. Epigenetic Priming with Decitabine Augments the Therapeutic Effect of Cisplatin on Triple-Negative Breast Cancer Cells through Induction of Proapoptotic Factor NOXA. Cancers. 2022. 14. 1. 248-248
  • Yasuko Kuribayashi-Hamada, Mariko Ishibashi, Atsushi Tatsuguchi, Toshio Asayama, Namiko Takada-Okuyama, Asaka Onodera-Kondo, Keiichi Moriya, Takehito Igarashi, Hiroyuki Onose, Sakae Tanosaki, et al. Clinicopathologic characteristics and A20 mutation in primary thyroid lymphoma. Journal of Nippon Medical School. 2022. 89. 3. 301-308
  • Mariko Ishibashi, Junichi Yamamoto, Takumi Ito, Hiroshi Handa, Mika Sunakawa-Kii, Koiti Inokuchi, Rimpei Morita, Hideto Tamura. Durvalumab Combined with Immunomodulatory Drugs (IMiD) Overcomes Suppression of Antitumor Responses due to IMiD-induced PD-L1 Upregulation on Myeloma Cells. Molecular Cancer Therapeutics. 2021. 20. 7. 1283-1294
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MISC (27):
  • 田村 秀人, 石橋 真理子, 高橋 秀実, 猪口 孝一. Novel Therapeutic Targets on the Surface of Myeloma Cells in Association with Marrow Microenvironment 多発性骨髄腫におけるSLAMファミリー分子を標的とした治療. 臨床血液. 2020. 61. 7. 818-826
  • 田村秀人, 石橋真理子, 高橋秀実, 猪口孝一. SLAM family proteins as therapeutic targets in multiple myeloma. 臨床血液. 2020. 61. 7
  • Mariko Ishibashi, Ryosuke Kinoshita, Koiti Inokuchi, Hiroshi Handa, Makoto Sasaki, Norio Komatsu, Yoichi Imai, Norina Hiroike, Junji Tanaka, Sakae Tanosaki, et al. Serum Soluble CD86, Still a Prognostic Factor in the Novel Agent Era in Multiple Myeloma Patients, Is Produced By Myeloma Cells with High CD86 Variant 3 Expression. BLOOD. 2019. 134
  • 砂川 実香, 石橋 真理子, 海渡 裕太, 木下 量介, 朝山 敏夫, 守屋 慶一, 半田 寛, 佐々木 純, 今井 陽一, 田中 紀奈, et al. 血清KL-6値は多発性骨髄腫の予後予測因子となりうる(KL-6 may be an excellent predictor of prognosis in multiple myeloma). International Journal of Myeloma. 2019. 9. 1. 86-86
  • 添田 沙織, 山下 卓也, 磯田 淳, 鈴木 一史, 木口 亨, 田中 紀奈, 田中 淳司, 佐々木 純, 小松 則夫, 安井 寛, et al. 実臨床における再発・難治性骨髄腫患者に対するERd療法の効果(Efficacy of elotuzumab plus lenalidomide/dexamethasone in patients with relapsed/refractory multiple myeloma in the real-world practice setting). International Journal of Myeloma. 2019. 9. 1. 146-146
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Books (4):
  • Bone marrow immune microenvironment in pathogenesis of multiple myeloma
    2023
  • 骨髄腫とインフラマソーム
    科学評論社 臨床免疫・アレルギー科 2022
  • 多発性骨髄腫におけるanti-BCMA CAR-T療法
    科学評論社 血液内科 2019
  • Expression and function of signaling lymphocytic activation molecule (SLAM) family molecules in multiple myeloma
    2017
Lectures and oral presentations  (56):
  • The multiple myeloma microenvironment triggers inflammasome activation in tolerogenic dendritic cells to promote disease progression
    (第55 日本免疫学会学術集会 2024)
  • Tolerogenic dendritic cells alter the immune microenvironment in multiple myeloma.
    (2023)
  • 多発骨髄腫の治療戦略の確立に向けて 免疫微小環境を理解する
    (Multiple Myeloma Web Seminar (ブリストルマイヤーズ招待講演) 2023)
  • Characteristics of tolerogenic dendritic cells in multiple myeloma microenvironment.
    (第81回日本癌学会学術集会 2023)
  • 多発性骨髄腫の免疫微小環境
    (2023)
more...
Professional career (1):
  • 理学博士
Work history (4):
  • 2022/10 - 現在 日本医科大学大学院 微生物学・免疫学 講師
  • 2022/10 - 現在 Nippon Medical School Department of Microbiology and Immunology
  • 2017/10 - 2022/09 Nippon Medical School Department of Microbiology and Immunology Research associate/ Assistant professor
  • 2010/04 - 2017/09 Nihon Medical School Department of Hematology postdoctoral fellow
Committee career (2):
  • 2019/05 - 現在 日本骨髄腫学会 代議員
  • 2021 - 日本骨髄腫学会 第46回学術集会 プログラム委員
Awards (9):
  • 2022/05 - 19th International Myeloma Workshop Travel Award
  • 2022/05 - 日本骨髄腫学会 プレナリー演題賞
  • 2021/09 - 日本医科大学 丸山記念研究助成
  • 2021/05 - 12th JSH International Symposium best poster award APRIL Upregulation in Myeloma Cells by Immunomodulatory Drugs Promotes Aggressive Myeloma.
  • 2021 - 日本私立学校振興・共済事業団 若手研究者奨励賞
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Association Membership(s) (4):
THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE SOCIETY OF MYELOMA ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  Japanese Cancer Association
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