Rchr
J-GLOBAL ID:201801015650728080   Update date: Jun. 25, 2024

Nakai Akiko

ナカイ アキコ | Nakai Akiko
Affiliation and department:
Job title: Assistant Professor
Homepage URL  (1): http://ird.ifrec.osaka-u.ac.jp/
Research field  (1): Immunology
Research keywords  (3): GPCR ,  Neuroimmunology ,  Immunology
Research theme for competitive and other funds  (3):
  • 2022 - 2025 The molecular mechanism of the crosstalk between the beta-2 adrenergic receptor and chemokine receptors in lymphocytes
  • 2019 - 2022 新たなGPCRシグナル伝達制御因子の機能阻害剤の探索
  • 2016 - 2019 走化性因子受容体の新たな制御因子の機能とその免疫系における役割
Papers (11):
  • Taiichiro Shirai, Akiko Nakai, Kazuhiro Suzuki. Chemoattractant receptor signaling in humoral immunity. International Immunology. 2024
  • Noam Ben-Shalom, Elad Sandbank, Lilach Abramovitz, Hadas Hezroni, Talia Levin, Estherina Trachtenberg, Nadav Fogel, Michael Mor, Ron Yefet, Liat Stoler-Barak, et al. β2-Adrenergic Signaling Promotes Higher-Affinity B Cells and Antibodies. Brain, behavior, and immunity. 2023
  • Taiichiro Shirai, Akiko Nakai, Emiko Ando, Jun Fujimoto, Sarah Leach, Takao Arimori, Daisuke Higo, Floris J. van Eerden, Janyerkye Tulyeu, Yu-Chen Liu, et al. Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex. Science Immunology. 2023. 8. 81
  • Akiko Nakai, Sarah Leach, Kazuhiro Suzuki. Control of immune cell trafficking through inter-organ communication. International Immunology. 2021. 33. 6. 327-335
  • Akiko Nakai, Jun Fujimoto, Haruhiko Miyata, Ralf Stumm, Masashi Narazaki, Stefan Schulz, Yoshihiro Baba, Atsushi Kumanogoh, Kazuhiro Suzuki. The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors. The Journal of experimental medicine. 2019. 216. 7. 1630-1647
more...
Lectures and oral presentations  (9):
  • The molecular mechanism of the crosstalk between the β2-adrenergic receptor and chemokine receptors in lymphocytes
    (2021)
  • The COMMD3/8 complex determines the specificity of GRK6 recruitment to chemoattractant receptors
    (MMCB2020+1)
  • Control of chemoattractant receptor signaling by the COMMD3/8complex
  • COMMD3/8複合体による走化性因子受容体シグナル伝達の制御
    (第42回分子生物学会年会)
  • The COMMD3/8 complex dictates the specificity of GRK6 recruitment to chemoattractant receptors
more...
Education (2):
  • 2011 - 2015 Osaka University Graduate School of Medicine
  • 2005 - 2011 Osaka Prefecture University School of Life and Environmental Sciences Department of Veterinary Sciences
Professional career (1):
  • 博士(医学) (大阪大学大学院医学系研究科)
Work history (2):
  • 2017/04 - 現在 Osaka University WPI Immunology Frontier Research Center
  • 2015/04 - 2017/03 Osaka University WPI Immunology Frontier Research Center
Awards (1):
  • 2015/03 - 大阪大学大学院医学系研究科 山村賞(博士課程最優秀者)
Association Membership(s) (2):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY
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