Ichiro Saito

2016 - 2020 Detection and application of morphologically disease-specific markers in autoimmune salivary gland inflammation

2017 - 2019 高齢者の唾液分泌促進を目指したフィトケミカルの効果の検討

2016 - 2019 Identification of reactive oxygen species generated by mental stress and examination of stress reduction method by antioxidant

2016 - 2019 Pathogenesis and regulation of herpes virus related diseases

2015 - 2018 Elucidation of the salivary secretion regulation mechanism through mitochondrial function control by estrogen

2015 - 2018 The molecular mechanism of salivary dysfunction amelioration by calorie restriction

2015 - 2018 Stemness and tumorigenesis of salivary gland myoepithelial cells

2014 - 2017 Evaluation of effectiveness of equol for salivary secretion and the elucidation of the action mechanism.

2014 - 2017 Genome-wide analysis of epigenetics in the sialadenitis from Sjogren's syndrome

2014 - 2017 Development of new treatment to improve gastrointestinal function by promotion of saliva secretion

2013 - 2016 Establishment of screening platform of depressive disorder for dentists

2013 - 2016 Pathological analysis of autoimmune sialadenitis using human dental pulp

2012 - 2015 Study of autoimmune reaction induced by Epstein-Brr virus (EBV)-encoded small RNA (EBER)

2011 - 2014 Analysis of salivary secretory function via Sirt1 activation

2011 - 2014 Clarification about the antidepressant effect of salivary gland BDNF due to chewing

2011 - 2013 Effects of resveratrol on salivary secretion

2011 - 2013 Evaluation for functional diet which enhances saliva secretion

2011 - 2013 Establishment of salivary gland regeneration for salivary gland hypofunction : Approach to regeneration of blood vessels using dental pulp cells

2011 - 2013 Differentiation of iPS cells into salivary glands

2011 - 2012 Transcription factors required for salivary gland regeneration

2009 - 2011 Mechanism of EBV induced salivary gland disorder via TLR

2008 - 2010 Genetic analysis of xerostomia associated with lifestyle-related diseases.

2008 - 2010 Evaluation of stemness on salivary gland side population cells

2008 - 2010 Protective effect of SOD on reactive oxygen species-induced salivary gland dysfunction.

2008 - 2010 A study of clustrin for the treatment of hyposalivation

2008 - 2010 The study on stressful lesion suppression mechanism of the BDNF derived from a salivary gland

2007 - 2009 Molecular genetics study of gutter-shaped root (GSR) in inbred mice using RNAi analysis.

2007 - 2008 Pathogenesis of Epstein-Barr virus on tissue specific autoimmune disease in humanized mice

2007 - 2008 Establishment of methods for diagnosis and treatment of subcutaneous mycosis and trial of network formation

2006 - 2007 酸化ストレスによる外分泌腺機能障害機構の解明

2006 - 2007 Establishment of the standard degree of oral function classified by age.

2006 - 2007 Investigation into the mechanism of tumorigenesis using p53-deficient epithelial cells

2005 - 2006 DEVELOPMENT OF CULTURE METHODS FOR EXOCRINE GLAND STEM CELLS USING GENE-TRANSDUCED FEEDER CELLS AND THEIR APPLICATION FOR TREATMENT

2005 - 2006 Identification of chromosomal region(s) influencing tooth root development in mouse

2005 - 2006 Searching the tissue specific autoimmune disease related gene by linkage analysis and establishment of a diagnosis method

2004 - 2005 The mechanism of exocrine gland disorder through estrogen and/or endocrine disruptors

2002 - 2003 Identification of animal model for autoimmune disease using conditional expression of transgene

2000 - 2003 Analysis of the mechanism of membranous proteolysis and the immunoregulation for Sjogren's syndrome

2000 - 2001 Enhanced lacrimation and salivation in prolactin transgenic rats

1998 - 1999 An organ-specific autoantigen for Sjogren's syndrome induced by Epstein-Barr virus activation

1996 - 1997 Establishment of in vitro model for the Epstein-Barr virus reactivation in Sjogren's syndrome

1995 - 1997 Detection of possible factors for the Epstein-Barr virus reactivation in Sjogren's syndrome

1994 - 1995 Analysis of lymphoproliferative disorders of Sjogren's syndrome

1991 - 1994 IMMUNOLOGICAL AND MOLECULAR STUDIES ON SECRETORY IGA

1993 - 1993 シェーグレン症候群の病因論に関するEBウイルスの分子機構の検討