Research field (2):
Bioorganic chemistry
, Structural/physical organic chemistry
Research keywords (3):
天然物化学
, 複素環化学
, 有機合成化学
Papers (25):
Kie Sakai, Taisei Soshima, Yuki Hirose, Fumito Ishibashi, Shotaro Hirao. Design, synthesis, and biological evaluation of novel benzo[6,7]indolo[3,4-c]isoquinolines as anticancer agents with topoisomerase I inhibition. Bioorganic and Medicinal Chemistry Letters. 2024. 104
Shotaro Hirao, Rumi Saeki, Toru Takahashi, Kento Iwai, Nagatoshi Nishiwaki, Yasushi Ohga. Synthesis of Unsymmetrical Ketones Using Chelation-Controlled Sequential Substitution of N-Triazinylamide/Weinreb Amide by Organometallic Reagents. ACS Omega. 2022. 7. 51. 48476-48483
Fumito Ishibashi, Tsutomu Fukuda, Shijiao Zha, Aya Hashirano, Shotaro Hirao, Masatomo Iwao. Concise synthesis and in vitro anticancer activity of benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-ones (BBPIs), topoisomerase I inhibitors based on the marine alkaloid lamellarin. Bioscience, Biotechnology, and Biochemistry. 2021. 85. 1. 181-191